Clinical observation on treatment of Tourette syndrome by integrative medicine

An-yuan Li; Shan Cong; Hong Lu; Ji-jun Li; Lin Zhao

doi:10.1007/s11655-009-0261-2

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Clinical observation on treatment of Tourette syndrome by integrative medicine

OriginalPaper | Updated：2021-08-27

- Clinical observation on treatment of Tourette syndrome by integrative medicine
- Clinical observation on treatment of Tourette syndrome by integrative medicine
- 中国结合医学杂志（英文版） 2009年15卷第4期页码：261-265
- Affiliations：
  
  1. Department of Integrative Medicine, Shandong Provincial Hospital Affiliated to Shandong University,Jinan,China
  2. Department of Pediatrics, Jining First People’s Hospital,Shandong,China
- Author bio：
- Funds：
  
  Supported by the Research Fund from Shandong Provincial Administration of Traditional Chinese Medicine (No. 2005064)
- DOI：10.1007/s11655-009-0261-2
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2009-8-18，
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Li, Ay., Cong, S., Lu, H. et al. Clinical observation on treatment of Tourette syndrome by integrative medicine., Chin. J. Integr. Med. 15, 261–265 (2009). https://doi.org/10.1007/s11655-009-0261-2

An-yuan Li, Shan Cong, Hong Lu, et al. Clinical observation on treatment of Tourette syndrome by integrative medicine[J]. Chinese Journal of Integrative Medicine, 2009,15(4):261-265.
Li, Ay., Cong, S., Lu, H. et al. Clinical observation on treatment of Tourette syndrome by integrative medicine., Chin. J. Integr. Med. 15, 261–265 (2009). https://doi.org/10.1007/s11655-009-0261-2 DOI：

An-yuan Li, Shan Cong, Hong Lu, et al. Clinical observation on treatment of Tourette syndrome by integrative medicine[J]. Chinese Journal of Integrative Medicine, 2009,15(4):261-265. DOI： 10.1007/s11655-009-0261-2.

摘要

To explore the clinical efficacy of integrative Chinese and Western medicine in treating Tourette syndrome (TS). Ninety children with TS were randomized into two groups by randomizing: digital table method: the 60 patients in the treated group were treated by Ningdong Granule (宁动颗粒

NDG) plus haloperidol

and the 30 in the control group treated by haloperidol alone. The course for both groups was 6 months. Conditions of the patients were estimated before and after treatment with Yale Global Tic Severity Scale (YGTSS)

the short-term efficacy

adverse reaction of treatment were assessed at the end of treatment

and the long-term efficacy as well as the recurrent rate were evaluated half a year after the treatment was ended. Of the 60 patients in the treated group

the treatment on 36 was evaluated as remarkably effective

21 as effective

and 3 as ineffective

the total effective rate being 95.0% (57/60)

while of the 30 patients in the control group

the corresponding data were 9

8 and 73.3% (22/30)

respectively

differences between groups in markedly effective rate and total effective rate were statistically significant (χ2=7.20

and χ2=6.85

P<0.01). The improvement on the condition of illness

motor tic and vocal tic

as well as the long-term efficacy of treatment were all better in the treated group than in the control group (P<0.05 or P<0.01). The incidence of adverse reaction and the recurrent rate in the treated group were 13.3% (8/60) and 8.3% (5/60) respectively

all were lower than those in the control group

36.7% (11/30) and 43.3 (13/30)

showing statistical significances (P<0.05 and P<0.01). Integrative medical treatment on TS was markedly effective in clinical practice with less adverse reaction and lower recurrent rate.

Abstract

NDG) plus haloperidol

the short-term efficacy

adverse reaction of treatment were assessed at the end of treatment

and the long-term efficacy as well as the recurrent rate were evaluated half a year after the treatment was ended. Of the 60 patients in the treated group

the treatment on 36 was evaluated as remarkably effective

21 as effective

and 3 as ineffective

the total effective rate being 95.0% (57/60)

while of the 30 patients in the control group

the corresponding data were 9

8 and 73.3% (22/30)

respectively

differences between groups in markedly effective rate and total effective rate were statistically significant (χ2=7.20

and χ2=6.85

P<0.01). The improvement on the condition of illness

motor tic and vocal tic

all were lower than those in the control group

36.7% (11/30) and 43.3 (13/30)

showing statistical significances (P<0.05 and P<0.01). Integrative medical treatment on TS was markedly effective in clinical practice with less adverse reaction and lower recurrent rate.

关键词

Tourette syndromeintegrative Chinese and western medical treatmentClinical Observation

Keywords

Tourette syndromeintegrative Chinese and western medical treatmentClinical Observation

references

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Li AY, Lu H, Sun R, Lu LL, Zhang XL, Wang P. Study on the pharmacodynamics of Ningdong granule for TS. J Chin Pediatr Integr Tradit West Med (Chin) 2009; 1:48–50.

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