Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction

Ya-chen Zhang; Rui-ming Chen; Bao-jing Lu; Mei-hua Zhao; Ye-zhi Rong

doi:10.1007/s11655-009-0333-3

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Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction

OriginalPaper | Updated：2021-08-27

- Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction
- Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction
- 中国结合医学杂志（英文版） 2009年15卷第5期页码：333-336
- Affiliations：
  
  1. Department of Cardiology, Xinhua Hospital Affiliated to the Medical College of Shanghai Jiao Tong University,Shanghai,China
  2. Department of Laboratory, Ruijin Hospital Affiliated to the Medical College of Shanghai Jiao Tong University,Shanghai,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-009-0333-3
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2009-10-3，
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Zhang, Yc., Chen, Rm., Lu, Bj. et al. Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction., Chin. J. Integr. Med. 15, 333–336 (2009). https://doi.org/10.1007/s11655-009-0333-3

Ya-chen Zhang, Rui-ming Chen, Bao-jing Lu, et al. Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction[J]. Chinese Journal of Integrative Medicine, 2009,15(5):333-336.
Zhang, Yc., Chen, Rm., Lu, Bj. et al. Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction., Chin. J. Integr. Med. 15, 333–336 (2009). https://doi.org/10.1007/s11655-009-0333-3 DOI：

Ya-chen Zhang, Rui-ming Chen, Bao-jing Lu, et al. Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction[J]. Chinese Journal of Integrative Medicine, 2009,15(5):333-336. DOI： 10.1007/s11655-009-0333-3.

摘要

To observe the effect of long-term application of Shengmai Capsule (生脉胶囊

SMC) on recovery of patients after myocardial infarction. A total of 120 myocardial infarction patients were: assigned into two groups. Changes of angina pectoris

electrocardiogram (ECG)

living capacity and heart function in patients were observed after 6-month treatment. The total effective rate in alleviating angina: pectoris was 90.0% and that in improving ECG figure was 93.3% in the treatment group

both were significantly higher than those in the control group

73.4% and 70.0% respectively (P<0.05). The Karnofsky Performance Status scores of heart function were increased and the Activity of Daily Living scores in living capacity decreased in both groups

but the improvements were better in the treatment group (P<0.01 and P<0.05). The parameters of cardiac function

including cardiac output

stroke volume

cardiac index and ejection fraction

were increased in both groups

but the increments in the treatment group were more significant (P<0.01 or P<0.05). Long-term application of SMC could effectively prevent and treat angina pectoris

improve the living capacity and accelerate the recovery of heart function in patients after myocardial infarction.

Abstract

To observe the effect of long-term application of Shengmai Capsule (生脉胶囊

SMC) on recovery of patients after myocardial infarction. A total of 120 myocardial infarction patients were: assigned into two groups. Changes of angina pectoris

electrocardiogram (ECG)

both were significantly higher than those in the control group

73.4% and 70.0% respectively (P<0.05). The Karnofsky Performance Status scores of heart function were increased and the Activity of Daily Living scores in living capacity decreased in both groups

but the improvements were better in the treatment group (P<0.01 and P<0.05). The parameters of cardiac function

including cardiac output

stroke volume

cardiac index and ejection fraction

were increased in both groups

but the increments in the treatment group were more significant (P<0.01 or P<0.05). Long-term application of SMC could effectively prevent and treat angina pectoris

improve the living capacity and accelerate the recovery of heart function in patients after myocardial infarction.

关键词

Shengmai Capsulemyocardial infarctionliving capacityheart function

Keywords

Shengmai Capsulemyocardial infarctionliving capacityheart function

references

Zhang YC, Chen RM, Zhao MH, Lu BJ, Rong YZ. Effect of Shengmai Injection on hemodynamics in patients with dilated cardiomyopathy. Chin J Integr Tradit West Med (Chin) 2002;22:277–279.

Gao ZY, Guo CY, Shi DZ, Chen KJ, Xu H, Wu TX. Effect of Shengmai Injection on the fatality rate of patients with acute myocardial infarction: a systematic review. Chin J Integr Tradit West Med (Chin) 2008;28:1069–1073.

Brezinski D, Stone PH, Muller JE, Tofler GH, Davis V, Parker C, et al. Prognostic significance of the Karnofsky Performance Status score in patients with acute myocardial infarction. Am Heart J 1991;121:1374–1381.

Zhang YC, Chen RM, Lu BJ, Rong YZ. Effect of Shengmai Injection on cardiac function and inflammatory reaction in patients with acute coronary syndrome. Chin J Integr Med 2008;14:107–110.

Deng YJ, Liang WX, Chen YB, Cheng SY, Liu WY. Influence of Shengmai Capsules on multiple cytokines in rats with chronic heart failure. J Beijing Univ Tradit Chin Med (Chin) 2008;31:378–381.

Li HY, Sun XL, Zong MR, Yin XD. Protective role of Shengmai Injection on reperfusion injury of myocardial ischemia in rabbits. Chin J Basic Med Tradit Chin Med (Chin) 2007; 13: 35–37.

Zhang YC, Chen J, Lu BJ, Rong YZ. Effects of Shengmai Injection solution on myocardial hypertrophy and calcium overload. Acad J Shanghai Second Med Univ (Chin) 2005;25:1022.

Deng YJ, Liang XW, Zhang W, Zheng YL, Cheng SY, Chen YB, et al. Effect of Shengmai Capsule on ventricular remodeling in rats with chronic congestive heart failure induced by pressure overload. J Guangzhou Univ Tradit Chin Med (Chin) 2008;25:142–146.

Zhang YC, Lu BJ, Zhao MH, Rong RZ, Chen RM. Effect of Shengmai Injection on vascular endothelial and heart functions in patients with coronary heart disease complicated with diabetes mellitus. Chin J Integr Med 2008;14:281–285.

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