Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol

Qian Chen; Li Ma; Wupu Akebaier

doi:10.1007/s11655-009-0431-2

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Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol

OriginalPaper | Updated：2021-08-27

- Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol
- Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol
- 中国结合医学杂志（英文版） 2009年15卷第6期页码：431-434
- Affiliations：
  
  Department of Endocrinology, Traditional Chinese Medcine Hospital of Xinjiang Uigur Municipality,Urumqi,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-009-0431-2
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2010-1-18，
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Chen, Q., Ma, L. & Akebaier, W. Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol., Chin. J. Integr. Med. 15, 431–434 (2009). https://doi.org/10.1007/s11655-009-0431-2

Qian Chen, Li Ma, Wupu Akebaier. Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol[J]. Chinese Journal of Integrative Medicine, 2009,15(6):431-434.
Chen, Q., Ma, L. & Akebaier, W. Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol., Chin. J. Integr. Med. 15, 431–434 (2009). https://doi.org/10.1007/s11655-009-0431-2 DOI：

Qian Chen, Li Ma, Wupu Akebaier. Clinical study on treatment of hyperuricaemia by retention enema of Chinese herbal medicine combined with allopurinol[J]. Chinese Journal of Integrative Medicine, 2009,15(6):431-434. DOI： 10.1007/s11655-009-0431-2.

摘要

To study the effect of retention enema of Chinese herbal medicine combined with allopurinol in treating hyperuricaemia (HUE). Seventy-eight patients with HUE were assigned to two: groups

the 40 patients in the treated group were treated with retention enema of Chinese herbal medicine combined with oral intake of allopurinol

and the 38 patients in the control group were treated with allopurinol alone. The therapeutic course for all was 6 weeks. The clinical efficacy

changes of symptoms

blood levels of uric acid and lipids

renal function

and 24 h urinary micro-albumin were observed. The total effective rate was: 92.5% in the treated group

which was significantly higher than that in the control group (68.4%

P<0.05). After treatment

the score of symptoms in the treated group decreased from 9.43±1.15 scores to 3.25±0.85 scores

significantly lower than that in the control group (9.75±1.43 scores vs 9.25±0.82 scores

P<0.01). Moreover

the post-treatment improvements in blood uric acid

blood lipids

renal function and 24h urinary micro-albumin in the treated group were all better than those in the control group (P<0.05 or P<0.01). Retention enema with: Chinese herbal medicine combined with allopurinol could obviously reduce the uric acid level in blood

improve patients’ renal function and lipid metabolism

and alleviate the clinical symptoms in patients with HUE.

Abstract

To study the effect of retention enema of Chinese herbal medicine combined with allopurinol in treating hyperuricaemia (HUE). Seventy-eight patients with HUE were assigned to two: groups

the 40 patients in the treated group were treated with retention enema of Chinese herbal medicine combined with oral intake of allopurinol

and the 38 patients in the control group were treated with allopurinol alone. The therapeutic course for all was 6 weeks. The clinical efficacy

changes of symptoms

blood levels of uric acid and lipids

renal function

and 24 h urinary micro-albumin were observed. The total effective rate was: 92.5% in the treated group

which was significantly higher than that in the control group (68.4%

P<0.05). After treatment

the score of symptoms in the treated group decreased from 9.43±1.15 scores to 3.25±0.85 scores

significantly lower than that in the control group (9.75±1.43 scores vs 9.25±0.82 scores

P<0.01). Moreover

the post-treatment improvements in blood uric acid

blood lipids

improve patients’ renal function and lipid metabolism

and alleviate the clinical symptoms in patients with HUE.

关键词

Chinese Herbal MedicineRetention Enemahyperuricaemia

Keywords

Chinese Herbal MedicineRetention Enemahyperuricaemia

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