Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats

Mayank Thakur; Shilpi Bhargava; Werner Praznik; Renate Loeppert; Vinod K. Dixit

doi:10.1007/s11655-009-0448-6

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Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats

OriginalPaper | Updated：2021-08-27

- Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats
- Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats
- 中国结合医学杂志（英文版） 2009年15卷第6期页码：448-453
- Affiliations：
  
  1. Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar, Madhya Pradesh,India
  2. Department of Chemistry, University of Natural and Applied Life Sciences,Vienna,Austria
- Author bio：
- Funds：
- DOI：10.1007/s11655-009-0448-6
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2010-1-18，
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Thakur, M., Bhargava, S., Praznik, W. et al. Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats., Chin. J. Integr. Med. 15, 448–453 (2009). https://doi.org/10.1007/s11655-009-0448-6

Mayank Thakur, Shilpi Bhargava, Werner Praznik, et al. Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats[J]. Chinese Journal of Integrative Medicine, 2009,15(6):448-453.
Thakur, M., Bhargava, S., Praznik, W. et al. Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats., Chin. J. Integr. Med. 15, 448–453 (2009). https://doi.org/10.1007/s11655-009-0448-6 DOI：

Mayank Thakur, Shilpi Bhargava, Werner Praznik, et al. Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunction in hyperglycemic male rats[J]. Chinese Journal of Integrative Medicine, 2009,15(6):448-453. DOI： 10.1007/s11655-009-0448-6.

摘要

To investigate the effects of Chlorophytum borivilianum (CB) on sexual dysfunction

loss of body weight

and lack of libido in hyperglycemic rats induced with streptozotocin or alloxan. Wistar strain male albino rats were divided into five groups of six animals each: the control group (2% polyvinylpyrollidone solution)

the streptozotocin control group (50 mg/kg)

the alloxan control group (100 mg/kg)

the streptozotocin + CB treated group (200 mg/kg)

and the alloxan + CB treated group (200 mg/kg). Only after confirming the induction of diabetes

the animals of test groups were treated with CB. The sexual behavior of male rats of in presence of female rat in a special cage was recorded. The effects of induced diabetes in control groups and on simultaneous extract treatment in CB treated groups were tested for sexual parameters. The parameters evaluated included mount

ejaculation

and intromission latencies/frequencies

hesitation time

and penile erection index. Parallel to this

using a separate set of similarly treated animals

the influence of diabetes and CB treatment on anabolism and weight of secondary sexual organs were determined on day 0 and day 28 of the treatment. CB extract treatment ameliorated the diabetes-induced dysfunction at 200 mg/kg dose. There was very low weight loss (P<0.05) in CB-treated animals as compared to the diabetic control. There was a very high latency time (P<0.05) in the diabetic animals

whereas the latency time was very low in CB-treated animals. Mount

intromission

and ejaculation frequencies were very high (P<0.01) in CB-treated animals

while streptozotocin and alloxan groups animals had a very significantly lower sexual behavior (P<0.05) compared to the normo-glycemic control group animals. CB can significantly ameliorate diabetes-induced sexual dysfunction. Polysaccharide and saponin-rich aqueous extract appears to have the most suitable effects on diabetes and its associated effects on sexual functionality.

Abstract

To investigate the effects of Chlorophytum borivilianum (CB) on sexual dysfunction

loss of body weight

the streptozotocin control group (50 mg/kg)

the alloxan control group (100 mg/kg)

the streptozotocin + CB treated group (200 mg/kg)

and the alloxan + CB treated group (200 mg/kg). Only after confirming the induction of diabetes

ejaculation

and intromission latencies/frequencies

hesitation time

and penile erection index. Parallel to this

using a separate set of similarly treated animals

whereas the latency time was very low in CB-treated animals. Mount

intromission

and ejaculation frequencies were very high (P<0.01) in CB-treated animals

关键词

Ayurvedic RasayanaChlorophytum borivilianumdiabetes induced sexual dysfunctionSafed Musli

Keywords

Ayurvedic RasayanaChlorophytum borivilianumdiabetes induced sexual dysfunctionSafed Musli

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