Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris

Qing-yong He; Jie Wang; Yun-ling Zhang; Yan-li Tang; Fu-yong Chu; Xing-jiang Xiong

doi:10.1007/s11655-010-0013-3

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Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris

OriginalPaper | Updated：2021-08-27

- Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris
- Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris
- 中国结合医学杂志（英文版） 2010年16卷第1期页码：13-18
- Affiliations：
  
  1. Cardiology Department of Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Traditional Chinese Medical Internal Medicine, Dongfang Hospital, Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Basic Research Program of China (973 Program, No. 2003CB517103), the Traditional Chinese Medicine-treated Characteristic and Dominant Diseases Program of China Academy of Chinese Medical Sciences (No. CACMS05Y0010)
- DOI：10.1007/s11655-010-0013-3
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-2-4，
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He, Qy., Wang, J., Zhang, Yl. et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris., Chin. J. Integr. Med. 16, 13–18 (2010). https://doi.org/10.1007/s11655-010-0013-3

Qing-yong He, Jie Wang, Yun-ling Zhang, et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris[J]. Chinese Journal of Integrative Medicine, 2010,16(1):13-18.
He, Qy., Wang, J., Zhang, Yl. et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris., Chin. J. Integr. Med. 16, 13–18 (2010). https://doi.org/10.1007/s11655-010-0013-3 DOI：

Qing-yong He, Jie Wang, Yun-ling Zhang, et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris[J]. Chinese Journal of Integrative Medicine, 2010,16(1):13-18. DOI： 10.1007/s11655-010-0013-3.

摘要

To observe the effect of Yiqi Yangyin Decoction (益气养阴方

YQYYD) on the quality of life (QOL) of patients with unstable angina pectoris (UAP). A total of 108 patients with UAP of qi-yin deficiency syndrome confirmed by coronary angiography were enrolled and assigned to the treated group (treated with YQYYD and conventional therapy of Western medicine) and the control group (treated with conventional therapy of Western medicine)

by the use of the PROC PLAN of the SAS 6.12 software

in a prospective

randomized

controlled design. The clinical total effective rate

symptom score

QOL scale [Seattle Angina Questionnaire (SAQ)] and incidence of important clinical events were defined as the observation indices to evaluate the interventional effect of YQYYD on the QOL of patients with UAP of the qi-yin deficiency syndrome. During the study

three cases dropped out in the treated group

one case dropped out in the control group

and 104 cases

including 51 cases in the treatment group and 53 cases in the control group

finished the trial. After four weeks of treatment

the total clinical effective rates in the treated group and the control group were 80.4% and 75.5% respectively

and there was no obvious difference between them (P>0.05). However

the symptom score of the treated group (9.31±2.02) was significantly lesser than that of the control group (11.62±3.04

P<0.05)

and the total score of the QOL scale of the treated group (68.76±5.74) was significantly higher than that of the control group (61.06±3.31

P<0.01). Among those in the treated group physical limitation

angina stability

angina frequency

and treatment satisfaction were significantly ameliorated when compared with the control group after treatment (P<0.05

P<0.01). The incidence of important clinical events in the treated group (3.9%) was lower than that in the control group (5.7%) during the 8-month follow-up period

but the difference was insignificant (P>0.05). YQYYD could improve the clinical symptoms of patients with UAP of qi-yin deficiency syndrome and greatly improve their QOL.

Abstract

To observe the effect of Yiqi Yangyin Decoction (益气养阴方

by the use of the PROC PLAN of the SAS 6.12 software

in a prospective

randomized

controlled design. The clinical total effective rate

symptom score

three cases dropped out in the treated group

one case dropped out in the control group

and 104 cases

including 51 cases in the treatment group and 53 cases in the control group

finished the trial. After four weeks of treatment

the total clinical effective rates in the treated group and the control group were 80.4% and 75.5% respectively

and there was no obvious difference between them (P>0.05). However

the symptom score of the treated group (9.31±2.02) was significantly lesser than that of the control group (11.62±3.04

P<0.05)

and the total score of the QOL scale of the treated group (68.76±5.74) was significantly higher than that of the control group (61.06±3.31

P<0.01). Among those in the treated group physical limitation

angina stability

angina frequency

and treatment satisfaction were significantly ameliorated when compared with the control group after treatment (P<0.05

P<0.01). The incidence of important clinical events in the treated group (3.9%) was lower than that in the control group (5.7%) during the 8-month follow-up period

but the difference was insignificant (P>0.05). YQYYD could improve the clinical symptoms of patients with UAP of qi-yin deficiency syndrome and greatly improve their QOL.

关键词

Yiqi Yangyin Decoctionunstable angina pectorisSeattle Angina Questionnaireimportant clinical events

Keywords

Yiqi Yangyin Decoctionunstable angina pectorisSeattle Angina Questionnaireimportant clinical events

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