Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution

Qi Wang; Xiao-juan Ren; Shi-lin Yao; Hong-dong Wu

doi:10.1007/s11655-010-0028-9

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Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution

OriginalPaper | Updated：2021-08-27

- Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution
- Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution
- 中国结合医学杂志（英文版） 2010年16卷第1期页码：28-32
- Affiliations：
  
  1. Medical Research Center of Constitution and Reproductive, Beijing University of Chinese Medicine,Beijing,China
  2. Department of Ache, General Hospital of Armed Police Forces,Beijing,China
  3. Anhui College of Traditional Chinese Medicine,Hefei,China
- Author bio：
- Funds：
  
  Supported by the National Basic Research Program of China (973 Program, No. 2005CB523501)
- DOI：10.1007/s11655-010-0028-9
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-2-4，
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Wang, Q., Ren, Xj., Yao, Sl. et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution., Chin. J. Integr. Med. 16, 28–32 (2010). https://doi.org/10.1007/s11655-010-0028-9

Qi Wang, Xiao-juan Ren, Shi-lin Yao, et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution[J]. Chinese Journal of Integrative Medicine, 2010,16(1):28-32.
Wang, Q., Ren, Xj., Yao, Sl. et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution., Chin. J. Integr. Med. 16, 28–32 (2010). https://doi.org/10.1007/s11655-010-0028-9 DOI：

Qi Wang, Xiao-juan Ren, Shi-lin Yao, et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution[J]. Chinese Journal of Integrative Medicine, 2010,16(1):28-32. DOI： 10.1007/s11655-010-0028-9.

摘要

To explore the relationship between yin-deficiency constitution (YDC) and biochemical indexes by way of observing the endocrinal and immune functions in subjects with YDC. On the basis of epidemiological investigation

60 subjects with YDC and 50 with gentle constitution (GC) were selected according to the pertinent criteria. From each subject

8 mL of fasting venous blood was drawn at 8:00–9:00 in the morning

with the serum separated by centrifugation 3 000 r/min for 5 min and preserved at −70°C in a freezer. Serum levels of corticosterone

cortisol

adrenocorticotrophic hormone (ACTH)

cyclic adenosine monophosphate (cAMP)

cyclic guanosine monophosphate (cGMP)

free triiodothyronine (FT3)

free thyroxine (FT4)

throtropic stimulation hormone

interleukin 1β (IL-1β) and interleukin 2 (IL-2) were detected by double-antibody sandwich ELISA; cAMP/cGMP ratio was calculated

and the difference between the two constitutions in terms of these indexes was analyzed. Serum FT3 was 4.16±1.38 pmol/L in subjects with YDC

which was higher than that in subjects with GC (3.71±0.55 pmol/L)

but levels of cortisol (124.58±45.36 ng/mL)

ACTH (58.92±14.55 pg/mL)

cGMP (66.00±18.02 pmol/mL) and FT4 (12.33±3.12 pmol/L) in YDC were lower than those in GC (13.43±2.31 pmol/L)

showing significant difference (P<0.05). YDC is related to some extent with the disturbances in the hypothalamus-pituitary-adrenal axis

hypothalamus-pituitary-thyroid axis

cyclic nucleoside system and immune function.

Abstract

60 subjects with YDC and 50 with gentle constitution (GC) were selected according to the pertinent criteria. From each subject

8 mL of fasting venous blood was drawn at 8:00–9:00 in the morning

with the serum separated by centrifugation 3 000 r/min for 5 min and preserved at −70°C in a freezer. Serum levels of corticosterone

cortisol

adrenocorticotrophic hormone (ACTH)

cyclic adenosine monophosphate (cAMP)

cyclic guanosine monophosphate (cGMP)

free triiodothyronine (FT3)

free thyroxine (FT4)

throtropic stimulation hormone

interleukin 1β (IL-1β) and interleukin 2 (IL-2) were detected by double-antibody sandwich ELISA; cAMP/cGMP ratio was calculated

and the difference between the two constitutions in terms of these indexes was analyzed. Serum FT3 was 4.16±1.38 pmol/L in subjects with YDC

which was higher than that in subjects with GC (3.71±0.55 pmol/L)

but levels of cortisol (124.58±45.36 ng/mL)

ACTH (58.92±14.55 pg/mL)

cGMP (66.00±18.02 pmol/mL) and FT4 (12.33±3.12 pmol/L) in YDC were lower than those in GC (13.43±2.31 pmol/L)

showing significant difference (P<0.05). YDC is related to some extent with the disturbances in the hypothalamus-pituitary-adrenal axis

hypothalamus-pituitary-thyroid axis

cyclic nucleoside system and immune function.

关键词

yin-deficiency constitutionendocrinal functionimmune function

Keywords

yin-deficiency constitutionendocrinal functionimmune function

references

Wang Q, ed. Chinese medical constitution 2008. Beijing: People’s Medical Publishing House; 2009:4, 458, 461.

Ma J, Fan QL, Gong JN, Zhu X. Regulation on Liuweidi huang decoction for rat macrophages. Pharm Clin Chin Mater Med (Chin) 1999;15(4):5–7.

Wang YT, Zhang WR, Song HP, Liu J, Zhang WH. Study on yin deficiency animal model induced by long-term overload swimming. China Arch Tradit Chin Med (Chin) 2003;21:1115.

Ling CQ, Chen Z, Yu CQ, Tan JX. Experimental observation on leukocytic glucocorticoid receptor in peripheral blood in 52 cases of yin- and yang-deficiency. J Tradit Chin Med (Chin) 1998;39:619–620.

Yang HJ, Zheng M, Zhang D. Study for change of glucocorticoid hormone receptor in hyperthyroidism with yin deficiency and effect of rehmanniae pill of six ingredients. Shenzhen J Integr Tradit Chin West Med (Chin) 2003;13:87–89.

Li NY, Li YY, Hong CX, Long XS. Exploration on the relationship between pathogenesis for yin-deficiency of acute myocardial infarction and immediate prognosis as well as its mechanism. Chin J Integr Tradit West Med (Chin) 2004;24:400–403.

Xu JH, Chen JF, Ma YL, Ding P. Studies on the relationship between Chinese traditional medicinal differential symptom—complex (Zheng) types and pituitary-adrenal axis hormone levels in NIDDM patients. J Radioimmunol (Chin) 2000;13:141–142.

Pan YF, Wang YD, Chen JF. Studies on the relationship between yin deficiency yang excess syndrome and adrenocorticotrophic hormone in the primary status of acute cerebral infarction. Modern J Integr Tradit Chin West Med (Chin) 2006;15:1788–1789.

Zhu PJ. Research on plasma adrenocorticotrophic hormone, cortisol and traditional Chinese medicine syndrome in nephrotic syndrome. Zhejiang J Integr Tradit Chin West Med (Chin) 1997;7:193–194.

Li NY. Relationship between plasma concentrations of atrial natriuretic polypeptide, cAMP and cGMP and deficiency and excess syndromes of TCM in patients with chronic heart failure. Chin J Tradit Med Sci Tech (Chin)2004;11:196–197.

Zhao YH, Shen G, Chai Y. Peri-operative dynamics of cyclic ribonucleotide in patients under stress state during cardiac surgery. J Emerg Med (Chin) 1999;8:170–171.

Li YZ. Research on kidney-deficiency syndrome of TCM. China J Basic Med Tradit Chin Med (Chin) 1996;2(5):56–60.

Fan WH, Yue GX, Ren XQ, Lu YQ, Tang S. Change a rat model with yin-diffiency of liver and kidney induced by slow irritation on hypothalamus-pituitary-thypoid gland and regulatory effect of herbs. Chin J Inf Tradit Chin Med (Chin) 2001;8(10):21–23.

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