The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation

Dong Gao; Li-ya Wu; Yu-huan Jiao; Wen-yuan Chen; Yan Chen; Ted J. Kaptchuk; Bo Lu; Jun Song; Ke-ji Chen

doi:10.1007/s11655-010-0050-y

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The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation

OriginalPaper | Updated：2021-08-27

- The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation
- The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation
- 中国结合医学杂志（英文版） 2010年16卷第1期页码：50-53
- Affiliations：
  
  1. Department of Integrative Medicine, Fujian University of Traditional Chinese Medicine,Fuzhou,China
  2. Experimental Research Center, China Academy of Chinese Medical Sciences,Beijing,China
  3. Harvard Medical School,Boston,USA
  4. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 30772877);Basic Research Fund of China Academy of Chinese Medical Sciences (No. ZZ2006039);Fujian Academy of Integrative Medicine Foundation (No. 3000-905010805)
- DOI：10.1007/s11655-010-0050-y
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-2-4，
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Gao, D., Wu, Ly., Jiao, Yh. et al. The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation., Chin. J. Integr. Med. 16, 50–53 (2010). https://doi.org/10.1007/s11655-010-0050-y

Dong Gao, Li-ya Wu, Yu-huan Jiao, et al. The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation[J]. Chinese Journal of Integrative Medicine, 2010,16(1):50-53.
Gao, D., Wu, Ly., Jiao, Yh. et al. The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation., Chin. J. Integr. Med. 16, 50–53 (2010). https://doi.org/10.1007/s11655-010-0050-y DOI：

Dong Gao, Li-ya Wu, Yu-huan Jiao, et al. The effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on in vitro endothelial progenitor cell tube formation[J]. Chinese Journal of Integrative Medicine, 2010,16(1):50-53. DOI： 10.1007/s11655-010-0050-y.

摘要

To observe the effect of Xuefu Zhuyu Decoction (血府逐瘀汤)-containing serum (XFZYD-CS) on endothelial progenitor cell (EPC) tube formation in vitro. Mononuclear cells from rat bone marrow were prepared in a Ficoll density gradient centrifuge. EPCs were separated by the differential attachment method

and observed with inverted microscope for the effect of XFZYD-CS on EPC tube formation. After one day

EPCs exposed to the serum containing 5%

10% and 15% XFZYD-CS formed typical tubes or vessel networks. The tube formation time was two days ahead of the control group and the size of most tubes in the serum groups was smaller than in the control group. XFZYD-CS could induce EPC angiogenesis and hasten tube formation

especially in capillary vessels. The study provides experimental evidence for the plausibility of Xuefu Zhuyu Decoction in the treatment of ischemic diseases.

Abstract

and observed with inverted microscope for the effect of XFZYD-CS on EPC tube formation. After one day

EPCs exposed to the serum containing 5%

especially in capillary vessels. The study provides experimental evidence for the plausibility of Xuefu Zhuyu Decoction in the treatment of ischemic diseases.

关键词

Xuefu Zhuyu Decoctionendothelial progenitor cellstube formation

Keywords

Xuefu Zhuyu Decoctionendothelial progenitor cellstube formation

references

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