Effect of Gan-Pi regulatory needling in treating chloasma

Hong-fei Shi; Bing Xu; Xi-chao Guo; Xia-wen Qiu; Yu-ping Zhang; Xiang-jie Ding

doi:10.1007/s11655-010-0066-3

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Effect of Gan-Pi regulatory needling in treating chloasma

OriginalPaper | Updated：2021-08-27

- Effect of Gan-Pi regulatory needling in treating chloasma
- Effect of Gan-Pi regulatory needling in treating chloasma
- 中国结合医学杂志（英文版） 2010年16卷第1期页码：66-70
- Affiliations：
  
  The First Affiliated Hospital of Medical College of Zhejiang University,Hangzhou,China
- Author bio：
- Funds：
  
  Supported by Project of Traditional Chinese Medicine Science and Technology of Zhejiang Province (No. 2006C159)
- DOI：10.1007/s11655-010-0066-3
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-2-4，
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Shi, Hf., Xu, B., Guo, Xc. et al. Effect of Gan-Pi regulatory needling in treating chloasma., Chin. J. Integr. Med. 16, 66–70 (2010). https://doi.org/10.1007/s11655-010-0066-3

Hong-fei Shi, Bing Xu, Xi-chao Guo, et al. Effect of Gan-Pi regulatory needling in treating chloasma[J]. Chinese Journal of Integrative Medicine, 2010,16(1):66-70.
Shi, Hf., Xu, B., Guo, Xc. et al. Effect of Gan-Pi regulatory needling in treating chloasma., Chin. J. Integr. Med. 16, 66–70 (2010). https://doi.org/10.1007/s11655-010-0066-3 DOI：

Hong-fei Shi, Bing Xu, Xi-chao Guo, et al. Effect of Gan-Pi regulatory needling in treating chloasma[J]. Chinese Journal of Integrative Medicine, 2010,16(1):66-70. DOI： 10.1007/s11655-010-0066-3.

摘要

To study the effect of Gan (肝)-Pi (脾) regulatory needling (GPRN) in treating chloasma and its influences on female sex hormones

superoxide dismutase (SOD)

lipid peroxide (LPO) and melanocyte-stimulating hormone (MSH). Ninety chloasma patients were equally randomized to three groups

the treatment group treated with GPRN

the control group treated with conventional Western medicine and the blank group untreated. Changes in the scores of skin lesion (area and color) and symptom

as well as blood levels of female sex hormones

MSH

SOD and LPO were observed and compared after 3 months of treatment. In the treatment group

the scores of skin lesion area and color were reduced from 2.76±0.96 and 2.48±0.78 before treatment to 1.42±0.42 and 1.03±0.41 after treatment

respectively

while in the control group they were from 2.78±1.06 and 2.53±0.88 to 1.58±1.23 and 1.28±0.96

respectively

all showing significant changes (P<0.05); the scores were insignificantly changed in the blank group (P>0.05). At the same time

the score of symptoms in the treatment group significantly improved after treatment (P<0.05)

significantly different from that of the other two groups. Comparison of female sex hormones among groups showed no significant differences either before or after treatment. The level of LPO decreased and SOD increased in both the treatment group and the control group significantly (all P<0.05)

but significant lowering of MSH was only seen in the treatment group (P<0.05). GPRN can effectively lessen the size and lighten the color of chloasma

improve the accompanying symptoms in patients and decrease LPO and MSH levels and increase the SOD level

but will not affect the level of the female sex hormones.

Abstract

To study the effect of Gan (肝)-Pi (脾) regulatory needling (GPRN) in treating chloasma and its influences on female sex hormones

superoxide dismutase (SOD)

lipid peroxide (LPO) and melanocyte-stimulating hormone (MSH). Ninety chloasma patients were equally randomized to three groups

the treatment group treated with GPRN

the control group treated with conventional Western medicine and the blank group untreated. Changes in the scores of skin lesion (area and color) and symptom

as well as blood levels of female sex hormones

MSH

SOD and LPO were observed and compared after 3 months of treatment. In the treatment group

the scores of skin lesion area and color were reduced from 2.76±0.96 and 2.48±0.78 before treatment to 1.42±0.42 and 1.03±0.41 after treatment

respectively

while in the control group they were from 2.78±1.06 and 2.53±0.88 to 1.58±1.23 and 1.28±0.96

respectively

all showing significant changes (P<0.05); the scores were insignificantly changed in the blank group (P>0.05). At the same time

the score of symptoms in the treatment group significantly improved after treatment (P<0.05)

but significant lowering of MSH was only seen in the treatment group (P<0.05). GPRN can effectively lessen the size and lighten the color of chloasma

improve the accompanying symptoms in patients and decrease LPO and MSH levels and increase the SOD level

but will not affect the level of the female sex hormones.

关键词

Clinical StudychloasmaGan-Pi regulatory needling

Keywords

Clinical StudychloasmaGan-Pi regulatory needling

references

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Shi HF, XU B. Clinical observation on the treatment of chloasma by Chinese herbs combined with acupuncture. Chin J Integr Med 2007;13:219–223.

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