Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension

Hao Li; Long-tao Liu; Wen-ming Zhao; Jian-gang Liu; Ming-jiang Yao; Yong-xiang Han; Yan-peng Shen; Xing-dong Liu; Li Liu; Xue-mei Wang; Lin-lin Cai; Jie Guan

doi:10.1007/s11655-010-0216-y

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Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension

OriginalPaper | Updated：2021-08-27

- Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension
- Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension
- 中国结合医学杂志（英文版） 2010年16卷第3期页码：216-221
- Affiliations：
  
  1. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Traditional Chinese Medicine Hospital of Yanqing County,Beijing,China
  3. Community Health Service Centers of Yanqing County,Beijing,China
- Author bio：
- Funds：
  
  Supported by “Eleventh Five-Year” National Science and Technology Support Program of Chinese Medicine Treatment of Common Diseases Project (No. 2007BAI20B07);Science and Technology Research Projects of Capital Medical Development Fund, (No. 03 II 01)
- DOI：10.1007/s11655-010-0216-y
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-8-8，
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Li, H., Liu, Lt., Zhao, Wm. et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension., Chin. J. Integr. Med. 16, 216–221 (2010). https://doi.org/10.1007/s11655-010-0216-y

Hao Li, Long-tao Liu, Wen-ming Zhao, et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension[J]. Chinese Journal of Integrative Medicine, 2010,16(3):216-221.
Li, H., Liu, Lt., Zhao, Wm. et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension., Chin. J. Integr. Med. 16, 216–221 (2010). https://doi.org/10.1007/s11655-010-0216-y DOI：

Hao Li, Long-tao Liu, Wen-ming Zhao, et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension[J]. Chinese Journal of Integrative Medicine, 2010,16(3):216-221. DOI： 10.1007/s11655-010-0216-y.

摘要

To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension (EISH). A multi-center

randomized

double-blinded controlled trail was adopted. A total of 270 cases of EISH were randomly divided into 3 groups: Chinese medicine group (CM)

combination group and Western medicine group (WM). The course of treatment was 4 weeks. The clinical blood pressure

integral of quality of life (SF-36 scale)

immunoglubin G (IgG)

microalbumin (mALB)

β2-microglobulin (β2-MG)

transferrin (TRF) and N-acetyl-β′-D-glucosa-minidase (NAG) in urine were determined before and after the treatment. After treatment

systolic blood pressure depressed significantly in each group (P<0.05)

and the combination group was superior to CM or WM group in depressing SBP (P<0.05); in each group

integral of quality of life improved in different degree

and combination group was superior to WM group in all 8 dimensions (P<0.05). The level of mALB and β2-MG in urine decreased in all groups (P<0.05)

and the combination group was superior to CM group or WM group in decreasing mALB (P<0.05). Chinese medical regimen has affirmative effect in treating EISH patients

and could lower the systolic blood pressure

improve quality of life and early renal impairment of the patients

and integrative medical regimen has superiority on account of cooperation

and deserves further study.

Abstract

randomized

double-blinded controlled trail was adopted. A total of 270 cases of EISH were randomly divided into 3 groups: Chinese medicine group (CM)

combination group and Western medicine group (WM). The course of treatment was 4 weeks. The clinical blood pressure

integral of quality of life (SF-36 scale)

immunoglubin G (IgG)

microalbumin (mALB)

β2-microglobulin (β2-MG)

transferrin (TRF) and N-acetyl-β′-D-glucosa-minidase (NAG) in urine were determined before and after the treatment. After treatment

systolic blood pressure depressed significantly in each group (P<0.05)

and the combination group was superior to CM or WM group in depressing SBP (P<0.05); in each group

integral of quality of life improved in different degree

and combination group was superior to WM group in all 8 dimensions (P<0.05). The level of mALB and β2-MG in urine decreased in all groups (P<0.05)

and the combination group was superior to CM group or WM group in decreasing mALB (P<0.05). Chinese medical regimen has affirmative effect in treating EISH patients

and could lower the systolic blood pressure

improve quality of life and early renal impairment of the patients

and integrative medical regimen has superiority on account of cooperation

and deserves further study.

关键词

hypertensionelderlyChinese MedicineIntegrative Medicinequality of lifeearly renal impairment

Keywords

hypertensionelderlyChinese MedicineIntegrative Medicinequality of lifeearly renal impairment

references

Yu JY, Li SQ. The detection methods of the early renal disease of hypertension. Med Recapitulate (Chin) 2006;12:828–829.

Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003;289:2560–2572.

Amendment Committee of Chinese Prevention and Treatment of Hypertension. China guideline for the prevention and Treatment of hypertension in 2005. (updated version, 2005). Beijing: People’s Medical Publishing House; 2006:20.

Li H, Cui L, Xu LR, Luo ZG. Clinical study on Jiangya Capsules for treatment of 24 cases of senile simple systolic hypertension. J Tradit Chin Med (Chin) 2004;45:26–28.

Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992;30:473–483.

Chobanian AV. Clinical practice Isolated systolic hypertension in the elderly. N Engl J Med 2007; 357:789–796.

Whitworth JA. Progression of renal failure — the role of hypertension. Ann Acad Med Singapore 2005;34:8–15.

Zhang XC, Chen T. The clinical application of urinary albumin detection on the diagnosis of early renal damage of hypertension. Lab Med Clin (Chin) 2006; 3:25–26.

Stam F, van Guldener C, Schalkwijk CG, ter Wee PM, Donker AJ, Stehouwer CD. Impaired renal function is associated with markers of endothelial dysfunction and increased inflammatory activity. Nephrol Dial Transplant 2003;18:892–898.

Tang MF. The clinical research of traditional and West integrative medical treatment of the renal damage of hypertension. Chin J Integr Med Cardio-/Cerebrovasc Dis (Chin) 2008;6:1265–1267.

Wan LL, Sun DX. The detection value of urinary protein and urinary enzyme for early diagnosis of renal damage of hypertensive. Chin Health Med (Chin) 2007;15:76–77.

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