MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis

Amrollah Ahmadi; Gholameza Habibi; Mehdi Farrokhnia

doi:10.1007/s11655-010-0270-1

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MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis

Letter | Updated：2021-08-27

- MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis
- MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis
- 中国结合医学杂志（英文版） 2010年16卷第3期页码：270-271
- Affiliations：
  
  1. Cancer Research Center of the Cancer Institue, Tehran University of Medical Sciences, Tehran,Iran
  2. Tehran,Iran
  3. Tehran University of Medical Sciences, Tehran,Iran
- Author bio：
- Funds：
- DOI：10.1007/s11655-010-0270-1
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-8-8，
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Ahmadi, A., Habibi, G. & Farrokhnia, M. MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis., Chin. J. Integr. Med. 16, 270–271 (2010). https://doi.org/10.1007/s11655-010-0270-1

Amrollah Ahmadi, Gholameza Habibi, Mehdi Farrokhnia. MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis[J]. Chinese Journal of Integrative Medicine, 2010,16(3):270-271.
Ahmadi, A., Habibi, G. & Farrokhnia, M. MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis., Chin. J. Integr. Med. 16, 270–271 (2010). https://doi.org/10.1007/s11655-010-0270-1 DOI：

Amrollah Ahmadi, Gholameza Habibi, Mehdi Farrokhnia. MS14, An Iranian herbal-marine compound for the treatment of multiple sclerosis[J]. Chinese Journal of Integrative Medicine, 2010,16(3):270-271. DOI： 10.1007/s11655-010-0270-1.

摘要

MS14 is a natural herbal-marine drug

which has shown to slow down or halt the progression of multiple sclerosis (MS). This drug consists of 90% Penaeus latisculatus

5% Apium graveolens

and 5% Hypericum perforatum L. Preclinically

the effects of MS14 have mostly been examined in an animal model of multiple sclerosis called experimental allergic encephalomyelitis (EAE). Clinical studies of the effects of MS14 in MS patients also showed that it could improve the patients’ quality of life. MS14 is a safe drug in MS patients and might also be effective in the treatment of other neurodegenerative disorders with the same mechanisms.

Abstract

MS14 is a natural herbal-marine drug

which has shown to slow down or halt the progression of multiple sclerosis (MS). This drug consists of 90% Penaeus latisculatus

5% Apium graveolens

and 5% Hypericum perforatum L. Preclinically

关键词

Multiple SclerosisMS14herbal

Keywords

Multiple SclerosisMS14herbal

references

Lutskii MA, Esauenko IE. Oxidant stress in the pathogenesis of multiple sclerosis. Neurosci Behav Physiol 2007;37:209–213.

Grigoriadis N, Ben-Hur T, Karussis D, Milonas I. Axonal damage in multiple sclerosis: a complex issue in a complex disease. Clin Neurol Neurosurg 2004;106:211–217.

Kos D, Kerckhofs E, Nagels G, D’hooghe MB, Ilsbroukx S. Origin of fatigue in multiple sclerosis: review of the literature. Neurorehabil Neural Repair 2008; 22:91–100.

Kulkarni AP, Kellaway LA, Kotwal GJ. Herbal complement inhibitors in the treatment of neuroinflammation: future strategy for neuroprotection. Ann NY Acad Sci 2005;1056:413–429.

Tafreshi AP, Ahmadi A, Ghaffarpur M, Mostafavi H, Rezaeizadeh H, Minaie B, et al. MS14 halts progressiveness of the disease in experimental allergic encephalomyelitis. Phytotherapy Res 2008;22:1083–1086.

Naseri M, Ahmadi A, Ghareghozlu K, Nabavi M, Faghihzadeh S, Ashtarian N, et al. Clinical and toxicological evaluation of MS14 natural product in patients with multiple sclerosis. Daneshvar Med (in Persian) 2007;14: 59–65.

Ahmadi A. In accordance with report of Atomic Energy Organization of Iran (AEOI), Research Division, Tehran, I.R. of Iran, Analysis of MS14, 2004.

Naseri M, Ahmadi A, Gharegozli K, Nabavi M, Faghihzadeh S, Ashtarian N, et al. A double blind, placebo-controlled, crossover study on the effect of MS14, an herbal-marine drug, on quality of life in patients with multiple sclerosis. J Med Plant Res 2009;3:271–275

Smith DK, Feldman EB, Feldman DS. Trace element status in multiple sclerosis. Am J Clin Nutr 1989;50:136–140.

Visconti A, Cotichini R, Cannoni S, Bocca B, Forte G, Ghazaryan A, et al. Concentration of elements in serum of patients affected by multiple sclerosis with first demyelinating episode: a six-month longitudinal follow-up study. Ann Ist Super Sanita 2005;41:217–222.

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