Clinical study on the treatment of gastroesophageal reflux by acupuncture

Chao-xian Zhang; Yong-mei Qin; Bao-rui Guo

doi:10.1007/s11655-010-0516-y

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Clinical study on the treatment of gastroesophageal reflux by acupuncture

OriginalPaper | Updated：2021-08-27

- Clinical study on the treatment of gastroesophageal reflux by acupuncture
- Clinical study on the treatment of gastroesophageal reflux by acupuncture
- 中国结合医学杂志（英文版） 2010年16卷第4期页码：298-303
- Affiliations：
  
  1. Department of Gastroenterology, First Hospital Affiliated to Xinxiang Medical College,Henan,China
  2. Department of Traditional Chinese Medicine, First Hospital Affiliated to Xinxiang Medical College,Henan,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-010-0516-y
  中图分类号：
- 纸质出版日期：2010，
  
  网络出版日期：2010-8-10，
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Zhang, Cx., Qin, Ym. & Guo, Br. Clinical study on the treatment of gastroesophageal reflux by acupuncture., Chin. J. Integr. Med. 16, 298–303 (2010). https://doi.org/10.1007/s11655-010-0516-y

Chao-xian Zhang, Yong-mei Qin, Bao-rui Guo. Clinical study on the treatment of gastroesophageal reflux by acupuncture[J]. Chinese Journal of Integrative Medicine, 2010,16(4):298-303.
Zhang, Cx., Qin, Ym. & Guo, Br. Clinical study on the treatment of gastroesophageal reflux by acupuncture., Chin. J. Integr. Med. 16, 298–303 (2010). https://doi.org/10.1007/s11655-010-0516-y DOI：

Chao-xian Zhang, Yong-mei Qin, Bao-rui Guo. Clinical study on the treatment of gastroesophageal reflux by acupuncture[J]. Chinese Journal of Integrative Medicine, 2010,16(4):298-303. DOI： 10.1007/s11655-010-0516-y.

摘要

To explore the clinical effificacy and safety of acupuncture in treating gastroesophageal reflux (GER). Sixty patients with confirmed diagnosis of GER were randomly assigned to two groups. The 30 patients in the treatment group were treated with acupuncture at acupoints Zhongwan (CV 12)

bilateral Zusanli (ST36)

Sanyinjiao (SP6)

and Neiguan (PC6)

once a day

for 1 week as a therapeutic course

with interval of 2–3 days between courses; the 30 patients in the control group were administered orally with omeprazole 20 mg twice a day and 20 mg mosapride thrice a day. The treatment in both group lasted 6 weeks. Patients’ symptoms and times of reflux attacking were recorded

the 24-h intraesophageal acid/bile reflflux were monitored

and the endoscopic feature of esophageal mucous membrane was graded and scored at three time points

i.e.

pre-treatment (T0)

immediately after ending the treatment course (T1) and 4 weeks after it (T2). Besides

the adverse reactions were also observed. Compared with those detected at T0

24-h intraesophageal pH and bile reflux

endoscopic grading score and symptom score were all decreased signifificantly at T1 in both groups similarly (P<0.01)

showing insignifificant difference between groups (P>0.05). These indices were reversed at T2 to high level in the control group (P<0.05)

but the reversion did not occur in the treatment group (P>0.05). No serious adverse reaction was found during the therapeutic period. Acupuncture can effectively inhibit the intraesophageal acid and bile reflflux in GER patients to alleviate patients’ symptoms with good safety and is well accepted by patients.

Abstract

bilateral Zusanli (ST36)

Sanyinjiao (SP6)

and Neiguan (PC6)

once a day

for 1 week as a therapeutic course

the 24-h intraesophageal acid/bile reflflux were monitored

and the endoscopic feature of esophageal mucous membrane was graded and scored at three time points

i.e.

pre-treatment (T0)

immediately after ending the treatment course (T1) and 4 weeks after it (T2). Besides

the adverse reactions were also observed. Compared with those detected at T0

24-h intraesophageal pH and bile reflux

endoscopic grading score and symptom score were all decreased signifificantly at T1 in both groups similarly (P<0.01)

showing insignifificant difference between groups (P>0.05). These indices were reversed at T2 to high level in the control group (P<0.05)

关键词

acupuncturegastroesophageal reflflux24-h intraesophageal pHbile reflflux

Keywords

acupuncturegastroesophageal reflflux24-h intraesophageal pHbile reflflux

references

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