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Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay
Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay
- 中国结合医学杂志（英文版） 2011年17卷第4期 页码：290-295
- Affiliations：
1. China Military Institute of Chinese Materia Medica,Beijing,China
2. Chengdu University of Traditional Chinese Medicine,Chengdu,China
3. Academy of Life Science and Technology, Kunming University of Science and Technology,Kunming,China
- Author bio：
- Funds：Supported by the Major State Basic Research Development Program of China (973 Program, No. 2007CB512607), the National Science Fund for Distinguished Young Scholars (No. 30625042), and National Science and Technology Major Project of the Ministry of Science and Technology of China (No. 2009ZX10005-017)
DOI：10.1007/s11655-011-0694-2
中图分类号：纸质出版日期：2011，
网络出版日期：2011-4-21，
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Jia, L., Zhao, Yl., Wang, Jb. et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay., Chin. J. Integr. Med. 17, 290–295 (2011). https://doi.org/10.1007/s11655-011-0694-2
Lei Jia, Yan-ling Zhao, Jia-bo Wang, et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay[J]. Chinese Journal of Integrative Medicine, 2011,17(4):290-295.
Jia, L., Zhao, Yl., Wang, Jb. et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay., Chin. J. Integr. Med. 17, 290–295 (2011). https://doi.org/10.1007/s11655-011-0694-2 DOI：
Lei Jia, Yan-ling Zhao, Jia-bo Wang, et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay[J]. Chinese Journal of Integrative Medicine, 2011,17(4):290-295. DOI： 10.1007/s11655-011-0694-2.
摘要
To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤
MHD) and Maxing Shigan Decoction (麻杏石甘汤
MXSGD)
both categorized both categorized MHD) and Maxing Shigan Decoction (both categorized MXSGD)
both categorized formulas but with different hot/cold natures. Oxygen consumption of mice was determined among three groups: MHD
MXSGD and the control; a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD
MXSGD
and their compositions. Meanwhile
the total anti-oxidant capability (T-AOC) activity were detected. After administration of MHD
the mice showed increased oxygen consumption (P<0.01). Compared with MHD group
the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P<0.05). There was no significant difference (P>0.05) among the remaining rates of MXSGD
MXSGD with high dose Gypsum Fibrosum (MXHGF) group
and MXSGD with low dose Gypsum Fibrosum (MXLGF) group mice. Compared with the MHD group
T-AOC activity of the mice in the Consensus Compositons group was significantly decreased (P=0.0494). Compared with the MXSGD group
T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly (P=0.0013). The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature. The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions. However
increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD.
Abstract
To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤
MHD) and Maxing Shigan Decoction (麻杏石甘汤
MXSGD)
both categorized both categorized MHD) and Maxing Shigan Decoction (both categorized MXSGD)
both categorized formulas but with different hot/cold natures. Oxygen consumption of mice was determined among three groups: MHD
MXSGD and the control; a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD
MXSGD
and their compositions. Meanwhile
the total anti-oxidant capability (T-AOC) activity were detected. After administration of MHD
the mice showed increased oxygen consumption (P<0.01). Compared with MHD group
the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P<0.05). There was no significant difference (P>0.05) among the remaining rates of MXSGD
MXSGD with high dose Gypsum Fibrosum (MXHGF) group
and MXSGD with low dose Gypsum Fibrosum (MXLGF) group mice. Compared with the MHD group
T-AOC activity of the mice in the Consensus Compositons group was significantly decreased (P=0.0494). Compared with the MXSGD group
T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly (P=0.0013). The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature. The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions. However
increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD.
关键词
Mahuang Decoction and its categorized formulaecold and hot nature of Chinese drugscomplex prescription compatibility law of Chinese medicinecold-hot pad differentiating assay
Keywords
Mahuang Decoction and its categorized formulaecold and hot nature of Chinese drugscomplex prescription compatibility law of Chinese medicinecold-hot pad differentiating assay
references
Zhou CP, Wang JB, Zhang XR, Zhao YL, Xia XH, Zhao HP, et al. Investigation on the differences between cold and hot nature of Coptis Chinensis Franch and its processed materials based on animal’s temperature tropism. Sci China Serices C: Life Sci (Chin) 2009;39:669–676.
Aguiar P, Mendonça L, Galhardo V. Open control: a free open source software for video tracking and automated control of behavioral mazes. J Neurosci Methods 2007;166:66–72.
Ma YC, Xiao HB, Zheng CY, Bi YG, MA BY, Zhang P, et al. Experimental study on the features of prescription—compounding of Mahuang Decoction. Res Tradit Chin Med 2002,18:36.
Liu YG, Luo JB. Effects of among compositions of Herba Ephedrae decoction on genic expression of 5-lipoxygenase activating protein, IL-4 and leukotriene C4 in asthmatic mice. Chin J Chin Mater Med (Chin) 2007;32:246–249.
Zhu QS, Liu L, Ren CQ, Zhang MY, Wang LM, Lu YZ. Anti-pyetic experiment of Mahuangtang compatibility. Heilongjiang Med Pharm (Chin) 2004;27:13–14.
Luo JB, Liu GQ, Mo ZX, Li, ZG. The effect of Mahuangtang on diaphoretic function in mice. Chin Arch Tradit Chin Med (Chin) 2005;23:1945–1946.
Liu GQ, Luo JB. Effects of Mahuang Decoction in different combinations on diaphoretic function in rats. Tradit Chin Drug Res Clin Pharmacol (Chin) 2005;16:318–320.
Li JL, Chen FL, Liu CM, Luo JB. Determination of ephedrine and pseudoephedrine in Mahuang Decoction by GC-MS and effect of compatible medicinal herbs on concentration of components in decoction. Chin Tradit Herb Drugs (Chin) 2002;4:21–23.
Zhang MY, Zhang CZ. Primary analysis on the recipe composition of de-property and remaining effect of Z Zhongjing. Guangming J Chin Med (Chin) 2007;22:34–35.
Xiao XH, Wang YY, ed. Study traditional Chinese medicine from the view of thermodynamics. In: Shen ZY, Wang MQ, eds. Forum of international bioinformatics and Chinese medicine. Singapore: Singapore Medical Health Press; 2004:74–79.
Zhou SH, Xiao XH, Zhao YL, Dai CM, Zhu JC, Liu Y. Biothermokinetic studies on four properties of traditional Chinese medicine: comparison of properties of Zuojinwan and Fanzuojin by microcalorimetry. Chin J Chin Mater Med (Chin) 2004;29:1183–1186.
Wang LZ, Li XC, Sun T. Preferred temperature, avoidance temperature and lethal temperature of tadpoles of the common giant toad (Bufogargarizans) and the Chinese forest frog (Rana chensinensis). Chin J Zool (Chin) 2005;40:23–27.
Gordon JG. Behavioral and autonomic thermoregulation in the rat following propylthiouracil-induced hypothyroidism. Pharmacol Biochem Behav 1997;58:231–236.
Liu JS, Wang DH, Sun RY. Metabolism and thermoregulation in three species of rodent from Northeastern China. J Thermal Bio (Chin) 2004;29:177–183.
Gordon CJ, Becker P, Killough P, Padnos B. Behavioral determination of the preferred foot pad temperature of the mouse. J Thermal Bio 2000;25:211–219.
Gordon CJ, Becker P, Ali JS. Behavioral thermoregulatory responses of single- and group-housed mice. Physiol Behav 1998;65:255–262.
Carlisle HJ, Dubuc PU, Stock MJ. Effects of epinephrine on thermoregulatory behavior in lean and obese Zucker rats in the cold. Pharmacol Biochem Behav 1995;51:255–261.
Zhao HP, Zhao YL, Wang JB, Li HB, Ren YS, Zhou CP, et al. Expression of the difference between Cold (Han) and Hot (Re) nature of Chinese medicines (Strobal and Rhubarb) based on the cold/hot plate differentiating assay. Sci China Serices C: Life Sci (Chin) 2009;39(8):1–6.
Gao XS. The drug-property analects of Chinese medicine. Beijing: People’s Medical Publishing House; 1992:179.
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