A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome

Song-ling Chu; Hong Fu; Jin-xia Yang; Geng-xin Liu; Pan Dou; Liang Zhang; Peng-fei Tu; Xue-mei Wang

doi:10.1007/s11655-011-0781-4

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A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome

OriginalPaper | Updated：2021-08-27

- A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome
- A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome
- 中国结合医学杂志（英文版） 2011年17卷第7期页码：492-498
- Affiliations：
  
  1. Integration of Chinese and Western Medicine Laboratory of the First Hospital, Graduate School of Integration of Chinese and Western Medicine, Beijing Medical University,Beijing,China
  2. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University,Beijing,China
- Author bio：
- Funds：
  
  Supported by the Major Project of Development of Biotic Resources in Yunnan Province (No. 2007YNCXB-01-01)
- DOI：10.1007/s11655-011-0781-4
  中图分类号：
- 纸质出版日期：2011，
  
  网络出版日期：2011-7-3，
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Chu, Sl., Fu, H., Yang, Jx. et al. A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome., Chin. J. Integr. Med. 17, 492–498 (2011). https://doi.org/10.1007/s11655-011-0781-4

Song-ling Chu, Hong Fu, Jin-xia Yang, et al. A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome[J]. Chinese Journal of Integrative Medicine, 2011,17(7):492-498.
Chu, Sl., Fu, H., Yang, Jx. et al. A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome., Chin. J. Integr. Med. 17, 492–498 (2011). https://doi.org/10.1007/s11655-011-0781-4 DOI：

Song-ling Chu, Hong Fu, Jin-xia Yang, et al. A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome[J]. Chinese Journal of Integrative Medicine, 2011,17(7):492-498. DOI： 10.1007/s11655-011-0781-4.

摘要

To explore the regulative efficacy of Pu’er tea (普洱茶) extract on metabolic syndrome. Ninety patients with metabolic syndrome were randomly divided into two groups

the intervention group administered with Pu’er tea extract

and the placebo group with placebo capsules. After 3 months’ treatment

body mass index

waist hip ratio

blood lipids

blood sugar

immune and inflammatory index

and oxidation index of the patients with metabolic syndrome were tested and analyzed. In the intervention group

the body mass index

waist-hip ratio

fasting and 2 h postprandial blood glucose

serum total cholesterol

triglycerides

low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome

and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein

tumor necrosis factor-α

and interleukin-6 were decreased in the intervention group. Interleukin-10 level was increased

MDA was decreased and superoxide dismutase was increased. Compared with before treatment and the placebo group

there were significant differences (P<0.05

P<0.01). Pu’er tea demonstrated excellent potential in improving central obesity

adjusting blood lipid

lowering blood sugar

regulating immunity and resisting oxidation. It can adjust the metabolic syndrome of different clinical phenotypes to different degrees

and is ideally fit for early prevention of metabolic syndrome.

Abstract

To explore the regulative efficacy of Pu’er tea (普洱茶) extract on metabolic syndrome. Ninety patients with metabolic syndrome were randomly divided into two groups

the intervention group administered with Pu’er tea extract

and the placebo group with placebo capsules. After 3 months’ treatment

body mass index

waist hip ratio

blood lipids

blood sugar

immune and inflammatory index

and oxidation index of the patients with metabolic syndrome were tested and analyzed. In the intervention group

the body mass index

waist-hip ratio

fasting and 2 h postprandial blood glucose

serum total cholesterol

triglycerides

low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome

and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein

tumor necrosis factor-α

and interleukin-6 were decreased in the intervention group. Interleukin-10 level was increased

MDA was decreased and superoxide dismutase was increased. Compared with before treatment and the placebo group

there were significant differences (P<0.05

P<0.01). Pu’er tea demonstrated excellent potential in improving central obesity

adjusting blood lipid

lowering blood sugar

regulating immunity and resisting oxidation. It can adjust the metabolic syndrome of different clinical phenotypes to different degrees

and is ideally fit for early prevention of metabolic syndrome.

关键词

teametabolic syndromerandomized controlled clinical study

Keywords

teametabolic syndromerandomized controlled clinical study

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