Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China

Feng-bin Liu; Xin-lin Chen; Li Guo; Xiao-bin Liu

doi:10.1007/s11655-011-0944-3

Your Location：

Home >

Browse articles >

Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China

OriginalPaper | Updated：2021-08-27

- Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China
- Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China
- 中国结合医学杂志（英文版） 2012年18卷第10期页码：737-745
- Affiliations：
  
  1. Department of Internal Medicine, The First Affiliated Hospital, Guangzhou University of Chinese Medicine,Guangzhou,China
  2. College of Basic Medical Science, Guangzhou University of Chinese Medicine,Guangzhou,China
  3. The Second Hospital, Liwan District of Guangzhou,Guangzhou,China
  4. The DENG Tietao Institute, Guangzhou University of Chinese Medicine,Guangzhou,China
- Author bio：
- Funds：
  
  Supported by the Major State Basic Research Development Program of China (973 Program, No. 2005CB523500), and the Key Project of the National 11th Five Year Research Program of China (No. 2006BAI04A12)
- DOI：10.1007/s11655-011-0944-3
  中图分类号：
- 纸质出版日期：2012，
  
  网络出版日期：2012-2-27，
Scan for full text
Liu, Fb., Chen, Xl., Guo, L. et al. Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China., Chin. J. Integr. Med. 18, 737–745 (2012). https://doi.org/10.1007/s11655-011-0944-3

Feng-bin Liu, Xin-lin Chen, Li Guo, et al. Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China[J]. Chinese Journal of Integrative Medicine, 2012,18(10):737-745.
Liu, Fb., Chen, Xl., Guo, L. et al. Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China., Chin. J. Integr. Med. 18, 737–745 (2012). https://doi.org/10.1007/s11655-011-0944-3 DOI：

Feng-bin Liu, Xin-lin Chen, Li Guo, et al. Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China[J]. Chinese Journal of Integrative Medicine, 2012,18(10):737-745. DOI： 10.1007/s11655-011-0944-3.

摘要

To evaluate a scale of patient-reported outcomes for the assessment of myasthenia gravis patients (MG-PRO) in China. A total of 100 MG patients were interviewed for the field testing. Another 56 MG patients were selected and assessed with the MG-PRO scale before treatment and at 1

2 and 4 weeks after treatment. The classical test theory and item response theory (IRT) were used to assess the psychometric characteristics of the MG-PRO scale. The MG-PRO scale included 4 dimensions: physical

psychological

social environment

and treatment. Confirmatory factor analysis showed that each dimension was consistent with the theoretical construct. The scores of the physical and psychological dimensions increased significantly at 1 week after treatment (P<0.05). All the dimension scores and the MG-PRO score increased significantly at 2 and 4 weeks after treatment (P<0.05). IRT showed that person separation indices were greater than 0.8

most of the item fit residual statistics were within ±2.5

and no item had uniform or non-uniform differential item functioning (DIF) between gender and age (<40

⩾40). The MG-PRO scale is valid for measuring the quality of life (QOL) of MG patients

with good reliability

validity

responsiveness

and good psychometric characteristics from IRT. It can be applied to evaluate the QOL of MG patients and to assess treatment effects in clinical trials.

Abstract

psychological

social environment

most of the item fit residual statistics were within ±2.5

and no item had uniform or non-uniform differential item functioning (DIF) between gender and age (<40

⩾40). The MG-PRO scale is valid for measuring the quality of life (QOL) of MG patients

with good reliability

validity

responsiveness

and good psychometric characteristics from IRT. It can be applied to evaluate the QOL of MG patients and to assess treatment effects in clinical trials.

关键词

myasthenia gravisquality of lifepatient-reported outcomeclassical test theoryitem response theory

Keywords

myasthenia gravisquality of lifepatient-reported outcomeclassical test theoryitem response theory

references

Conti-Fine BM, Milani M, Kaminski HJ. Myasthenia gravis: past, present, and future. J Clin Invest 2006;116:2843–2854.

Jaretzki A, Barohn RJ, Ernstoff RM, Kaminski HJ, Keesey JC, Penn AS, et al. Myasthenia gravis recommendations for clinical research standards. Ann Thorac Surg 2000;70:327–334.

Rostedt A, Padua L, Stalberg EV. Correlation between regional myasthenic weakness and mental aspects of quality of life. Eur J Neurol 2006;13:191.

Paul RH, Nash JM, Cohen RA, Gilchrist JM, Goldstein JM. Quality of life and well-being of patients with myasthenia gravis. Muscle Nerve 2001;24:512–516.

Twork S, Wiesmeth S, Klewer J, Pohlau D, Kugler J. Quality of life and life circumstances in German myasthenia gravis patients. Health Qual Life Outcomes 2010;8:129.

Kulkantrakorn K, Jarungkiatkul W. Quality of life of myasthenia gravis patients. J Med Assoc Thai 2010;93:1167–1171.

Padua L, Evoli A, Aprile I, Caliandro P, Mazza S, Padua R, et al. Health-related quality of life in patients with myasthenia gravis and the relationship between patientoriented assessment and conventional measurements. Neurol Sci 2001;22:363–369.

Padua L, Evoli A, Aprile I, Caliandro P, Batocchi AP, Punzi C, et al. Myasthenia gravis outcome measure: development and validation of a disease-specific self-administered questionnaire. Neurol Sci 2002;23:59–68.

Padua L, Galassi G, Ariatti A, Aprile I, Caliandro P, Evoli A, et al. Myasthenia gravis self-administered questionnaire: development of regional domains. Neurol Sci 2005;25:331–336.

Mullins LL, Carpentier MY, Paul RH, Sanders DB. Diseasespecific measure of quality of life for myasthenia gravis. Muscle Nerve 2008;38:947–956.

Burns TM, Conaway MR, Cutter GR, Sanders DB. Less is more, or almost as much: a 15-item quality-of-life instrument for myasthenia gravis. Muscle Nerve 2008;38:957–963.

Busch C, Machens A, Pichlmeier U, Emskotter T, Izbicki JR. Long-term outcome and quality of life after thymectomy for myasthenia gravis. Ann Surg 1996;224:225–232.

Xue ZQ, Wang RW, Jiang YG, Ma Z, Zhao YP, Tan QY. Long-term quality of life of adult patients with myasthenia gravis after thymectomy. Acta Acad Med Milit Tertiae (Chin) 2004;26:817–819.

The WHOQOL Group. Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychol Med 1998;28:551–558.

World Health Organization. The World Health Organization quality of life assessment (WHOQOL): development and general psychometric properties. Soc Sci Med 1998;46:1569–1585.

Saxena S, Orley J. Quality of life assessment: the World Health Organization perspective. Eur Psychiatry 1997;12S3:263s–266s.

Guo L, Liu FB, Chen XL. Item selection of patient-reported outcome scale for myasthenia gravis. J Guangzhou Univ Tradit Chin Med (Chin) 2009;26:570–573.

Padua L, Stalberg E, LoMonaco M, Evoli A, Batocchi A, Tonali P. SFEMG in ocular myasthenia gravis diagnosis. Clin Neurophysiol 2000;111:1203–1207.

Chen XL, Liu FB, Guo L, Liu XB. Development of patient-reported outcome scale for myasthenia gravis: a psychometric test. J Chin Integr Med (Chin) 2010;8:121–125.

Andrich D, Sheridan B, Luo G, eds. RUMM: Rasch unidimensional measurement model. Perth, Western Australia: Measurement, Assessment and Evaluation Laboratory; 1996.

Andrich D, Sheridan B, Luo G. RUMM2010: a windows interactive program for analysing data with Rasch unidimensional models for measurement. Perth, Western Australia: RUMM Laboratory; 2000.

Andrich D. A rating formulation for ordered response categories. Psychometrika 1978;43:561–573.

Masters GN. A Rasch model for partial credit scoring. Psychometrika 1982;47:149–174.

De Ayala RJ, Kim SH, Stapleton LM, Dayton CM. A reconceptualization of differential item functioning. Montreal, Quebec, Canada: Annual Meeting of the American Educational Research Association; April 19–23, 1999.

Leung KK, Wu EC, Lue BH, Tang LY. The use of focus groups in evaluating quality of life components among elderly Chinese people. Qual Life Res 2004;13:179–190.

FULL TEXT LINK

More>

浏览量

904

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Standardized treatment of chinese medicine decoction for cancer pain patients with opioid-induced constipation: A multi-center prospective randomized controlled study

Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease

Advising on Preferred Reporting Items for patient-reported outcome instrument development: the PRIPROID

Effects of Chinese medicine five-element music on the quality of life for advanced cancer patients: A randomized controlled trial

Chinese medicine improves postoperative quality of life in endometriosis patients: A randomized controlled trial