Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats

Shu-yu Zhang; Gui-ying Peng; Li-gang Gu; Zi-mu Li; Sheng-jun Yin

doi:10.1007/s11655-011-0946-1

Your Location：

Home >

Browse articles >

Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats

OriginalPaper | Updated：2021-08-27

- Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats
- Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats
- 中国结合医学杂志（英文版） 2013年19卷第3期页码：212-216
- Affiliations：
  
  Department of Immunology and Microbiology, School of Basic Medical Sciences, Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 30701105) and Beijing Municipal Educational Fund [(2007) No.20]
- DOI：10.1007/s11655-011-0946-1
  中图分类号：
- 纸质出版日期：2013，
  
  网络出版日期：2012-1-12，
Scan for full text
Zhang, Sy., Peng, Gy., Gu, Lg. et al. Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats., Chin. J. Integr. Med. 19, 212–216 (2013). https://doi.org/10.1007/s11655-011-0946-1

Shu-yu Zhang, Gui-ying Peng, Li-gang Gu, et al. Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats[J]. Chinese Journal of Integrative Medicine, 2013,19(3):212-216.
Zhang, Sy., Peng, Gy., Gu, Lg. et al. Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats., Chin. J. Integr. Med. 19, 212–216 (2013). https://doi.org/10.1007/s11655-011-0946-1 DOI：

Shu-yu Zhang, Gui-ying Peng, Li-gang Gu, et al. Effect and mechanisms of Gong-tone music on the immunological function in rats with Liver (Gan)-qi depression and Spleen (Pi)-qi deficiency syndrome in rats[J]. Chinese Journal of Integrative Medicine, 2013,19(3):212-216. DOI： 10.1007/s11655-011-0946-1.

摘要

To investigate the effects and mechanisms of Gong-tone music on the immunological function in rats with the Chinese medicine syndrome of Liver (Gan)-qi stagnation and Spleen (Pi)-qi deficiency (LSSD). Twenty five male Wistar rats of SPF grade were randomly divided into 5 groups: normal group

model group

Xiaoyao Powder (逍遥散) group

Gong-tone group and combined group (the combination of Gong-tone and Xiaoyao Powder)

with 5 rats in each group. The rat model for the Chinese medicine syndrome of LSSD was induced by chronic bandage and irregular diet. The course of treatment was 21 days. After the treatment

the levels of serum gastrin and IgG were detected by enzyme-linked immunoabsorbent assay (ELISA). Phagocytosis of macrophages was detected by the neutral red uptake assay and T cell proliferation was investigated by 3-(4

5-dimethylthiazolyl)-2

5-diphenyltetrazolium bromide (MTT) assay. The serum gastrin

macrophage phagocytosis

IgG level and proliferation ability of T cells in the model group were significantly decreased compared with those in the normal group (P <0.05). Compared with those in the model group

the serum levels of gastrin

macrophage phagocytosis

IgG level and proliferation ability of T cells in Gong-tone

Xiaoyao Powder

and combined groups were significantly increased (P <0.05). The combined group was superior to either Gong-tone group or Xiaoyao Powder group. Gong-tone music may upregulate the immunological function and play a role in adjuvant therapy in the Chinese syndrome of LSSD.

Abstract

model group

Xiaoyao Powder (逍遥散) group

Gong-tone group and combined group (the combination of Gong-tone and Xiaoyao Powder)

with 5 rats in each group. The rat model for the Chinese medicine syndrome of LSSD was induced by chronic bandage and irregular diet. The course of treatment was 21 days. After the treatment

5-dimethylthiazolyl)-2

5-diphenyltetrazolium bromide (MTT) assay. The serum gastrin

macrophage phagocytosis

IgG level and proliferation ability of T cells in the model group were significantly decreased compared with those in the normal group (P <0.05). Compared with those in the model group

the serum levels of gastrin

macrophage phagocytosis

IgG level and proliferation ability of T cells in Gong-tone

Xiaoyao Powder

关键词

Gong-tone musicstagnation of liver-qi and deficiency of spleen-qiImmunological FunctionChinese Medicinefive-element music therapy

Keywords

Gong-tone musicstagnation of liver-qi and deficiency of spleen-qiImmunological FunctionChinese Medicinefive-element music therapy

references

Zhu Q, Han XL. Study on advantages and prospects of five elements music in treating the sub-health. Chin J Convalescent Med (Chin) 2009;18:250–251.

Núñez MJ, Mañá P, Liñares D, Riveiro MP, Balboa J, Suárez-Quintanilla J, et al. Music, immunity and cancer. Life Sci 2002:71:1047–1057.

Leardi S, Pietroletti R, Angeloni G, Necozione S, Ranalletta G, Del Gusto B. Randomized clinical trial examining the effect of music therapy in stress response to day surgery. Br J Surg 2007;94:943–947.

le Roux FH, Bouic PJ, Bester MM. The effect of Bach’s magnificat on emotions, immune, and endocrine parameters during physiotherapy treatment of patients with infectious lung conditions. J Music Ther 2007;44:156–168.

Conrad C, Niess H, Jauch KW, Bruns CJ, Hartl W, and Welker L. Overture for growth hormone: requiem for interleukin-6? Crit Care Med 2007;35:2709–2713.

Jin R, Liu G, Yuan LX. Application therapy of music treatment in TCM clinic and New explanation on it. Chin Assoc Tradit Chin Med (Chin) 2005;23:400–406.

Xiang CY, Guo Q, Liao J, Wang SG, Yang YF, Feng YH. Effect of therapy of traditional Chinese medicine five element music and electroacupuncture on the depression levels of cancer patients. Chin J Nurs (Chin) 2006;41:969–972.

Chai KF, ed. Fundamental theory of traditional Chinese medicine. Beijing: People’s Medical Publishing House; 2007:163–170.

Wang TF, Wang JJ, Xue XL, Han P, Zhang YJ, Li GR, et al. Distribution characteristics of traditional Chinese medicine syndromes and their elements in people with subhealth fatigue. J Chin Integr Med (Chin) 2010;8:220–223.

Liang Y, Chen JX, Guo XL, Yue GX, Yang MJ, Ge GL. Effect of Xiaoyaosan on ultrastructure of neurons in limbic system of rats with liver depression and spleen deficiency syndrome caused by chronic immobilization stress. China J Tradit Chin Med Pharm (Chin) 2009;24:577–581.

Cai QL, Peng GY, Bu LY, Lin YH, Zhang LH, Lustigmen S, et al. Immunogenicity and in vitro protective efficacy of a polyepitope Plasmodium falciparum candidate vaccine constructed by epitope shuffling. Vaccine 2007;25:5155–5165.

Cao QZ, Lin ZB. Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide. Acta Pharmacol Sin 2004;25:833–838.

Li JJ, Li XH, Wang SX, Bai MH, Chen JX. Therapeutic action of Xiaoyao San on Experimental white rats with stagnation of the liver-qi and deficiency of the spleen. Jinlin J Tradit Chin Med (Chin) 2009;29:901–903.

Yue LF, Ding J, Chen JX, Yue GX, Liang Y, Huo SK, et al. Establishment and review of rat model of syndrome of liver depression with spleen insufficiency. J Beijing Univ Tradit Chin Med (Chin) 2008;31:396–400.

Yan Y, Xie M, Gao XL, Wang YJ, Wang TS. The action of Chaihu Shugan Powder, Sijunzi Decoction and Chaishu Sijun Decoction on apperant GYPX syndrome of liver-qi stagnation and spleen-qi deficiency in rat. Chin J Tradit Med Formul (Chin) 2010;16:84–87.

Chen JX, Yang WY. Study on nerve-endocrine-immune network and its relation with liver of Chinese medicine. J Beijing Univ Tradit Med (Chin) 1995;18:7–10.

Zhang DB, ed. Fundamental theory of traditional Chinese medicine. Beijing: China Press of Traditional Chinese Medicine; 2007:3–4.

Ji LJ, ed. Spleen-stomach theory in traditional Chineses medicine. Beijing: Publishing House of Ancient Chinese Medical Books; 2001:4–74.

Lefranc F, Camby I, Belot N, Bruyneel E, Chaboteaux C, Brotchi J, et al. Gastrin significantly modifies the migratory abilities of experimental glioma cells. Lab Invest 2002;82:1241–1252.

de la Fuente M, Drummond J, del Rio M, Carrasco M, Hernanz A. Modulation of murine peritoneal macrophage functions by gastrin. Peptides 1996;17:219–224.

FULL TEXT LINK

More>

浏览量

842

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Future view and development of immunology: Exploring the immunology based on Chinese medicine and culture

Cost-effectiveness analysis of combined Chinese medicine and Western medicine for ischemic stroke patients

Objective tongue inspection on 142 liver cancer patients with damp-heat syndrome

Effect of Ermiao Recipe (二妙方) with medicinal guide Angelicae Pubescentis Radix on promoting the homing of bone marrow stem cells to treat cartilage damage in osteoarthritis rats

Effects of Jianpi Jiedu Recipe (健脾解毒方) on reversion of P-glycoprotein-mediated multidrug resistance through COX-2 pathway in colorectal cancer