A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)

Chuan-jian Lu; Yu Xiang; Xiu-li Xie; Mei-ling Xuan; Ze-hui He

doi:10.1007/s11655-012-1020-3

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A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)

OriginalPaper | Updated：2021-08-27

- A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)
- A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)
- 中国结合医学杂志（英文版） 2012年18卷第3期页码：186-191
- Affiliations：
  
  Department of Dermatology, Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou,China
- Author bio：
- Funds：
  
  Supported by the Financial Industry Technology Research and Development Program of Guangdong Province (No. 201105)
- DOI：10.1007/s11655-012-1020-3
  中图分类号：
- 纸质出版日期：2012，
  
  网络出版日期：2012-4-2，
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Lu, Cj., Xiang, Y., Xie, Xl. et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)., Chin. J. Integr. Med. 18, 186–191 (2012). https://doi.org/10.1007/s11655-012-1020-3

Chuan-jian Lu, Yu Xiang, Xiu-li Xie, et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)[J]. Chinese Journal of Integrative Medicine, 2012,18(3):186-191.
Lu, Cj., Xiang, Y., Xie, Xl. et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)., Chin. J. Integr. Med. 18, 186–191 (2012). https://doi.org/10.1007/s11655-012-1020-3 DOI：

Chuan-jian Lu, Yu Xiang, Xiu-li Xie, et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)[J]. Chinese Journal of Integrative Medicine, 2012,18(3):186-191. DOI： 10.1007/s11655-012-1020-3.

摘要

To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI

Visual Analogue Scale (VAS)

Dermatology Life Quality Index (DLQI)

Self-rating Depression Scale (SDS)

and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention. The PASI reduction rate in the treatment group was 74.4% (32/43)

which was higher than that in the control group (36.6%

15/41

P<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group P<0.01). With stratified analysis

there were significant differences between the PASI scores in the following subgroups: age 18–30

baseline PASI>10 and stable stage (P<0.05). DLQI decreased in both groups on some categories after treatment

but there were no significant differences between the two groups in SDS

SAS and VAS (P >0.05). No obvious adverse reactions were found in either group. The therapeutic effect of auricular therapy combined with Optimized Yinxieling Formula was superior to Optimized Yinxieling Formula alone with no obvious adverse reaction.

Abstract

Visual Analogue Scale (VAS)

Dermatology Life Quality Index (DLQI)

Self-rating Depression Scale (SDS)

and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention. The PASI reduction rate in the treatment group was 74.4% (32/43)

which was higher than that in the control group (36.6%

15/41

P<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group P<0.01). With stratified analysis

there were significant differences between the PASI scores in the following subgroups: age 18–30

baseline PASI>10 and stable stage (P<0.05). DLQI decreased in both groups on some categories after treatment

but there were no significant differences between the two groups in SDS

关键词

psoriasis vulgarisauricular therapyoptimized Yinxieling Formulaefficacy

Keywords

psoriasis vulgarisauricular therapyoptimized Yinxieling Formulaefficacy

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