FOLLOWUS
1. Department of Cardiovascular Diseases, Wuxi Municipal Hospital of Traditional Chinese Medicien, Wuxi City,Jiangsu Province,China
2. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
纸质出版日期:2012,
网络出版日期:2012-4-2,
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Yang, Qy., Chen, Kj., Lu, S. et al. Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure., Chin. J. Integr. Med. 18, 235–240 (2012). https://doi.org/10.1007/s11655-012-1022-1
Qing-you Yang, Ke-ji Chen, Shu Lu, et al. Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure[J]. Chinese Journal of Integrative Medicine, 2012,18(3):235-240.
Yang, Qy., Chen, Kj., Lu, S. et al. Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure., Chin. J. Integr. Med. 18, 235–240 (2012). https://doi.org/10.1007/s11655-012-1022-1 DOI:
Qing-you Yang, Ke-ji Chen, Shu Lu, et al. Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure[J]. Chinese Journal of Integrative Medicine, 2012,18(3):235-240. DOI: 10.1007/s11655-012-1022-1.
This paper reviewed the retrieved literature published in the last 10 years
regarding the mechanism of Radix Astragalus in treating heart failure
in aspects of myocardial contraction improvement
cardiac muscle cell protection
neuro-endocrinal system regulation
relative cytokine regulation
and left ventricular remodeling inhibition
etc.
This paper reviewed the retrieved literature published in the last 10 years
regarding the mechanism of Radix Astragalus in treating heart failure
in aspects of myocardial contraction improvement
cardiac muscle cell protection
neuro-endocrinal system regulation
relative cytokine regulation
and left ventricular remodeling inhibition
etc.
Radix Astragalusheart failuremechanism of actionreview
Radix Astragalusheart failuremechanism of actionreview
Liu JX, Ma XB, Wang YH, Wang RZ, He M, Zhao DY. Influence of Astragalus Injection on heart function and Na+-K+-ATPase activity in rats in vitro. Chin J New Drugs Clin Remed (Chin) 1999;18:370–372.
Zhou JY, Fan Y, Kong JL, Wu DZ, Hu ZB. Effects of components isolated from Astragalus membranaceus Bunge on cardiac function injured by myocardial ischemia reperfusion in rats. China J Chin Mater Med (Chin) 2000;25:370–372.
Chen SH, Lu GY, Fu HY, Li LW, Lou ZH, Zhang XD, et al. Effects of the active ingredients of “Huangqi Shenmai Decoction” on ATPase and Ca2+ in myocardial ischemia rats. Shanghai J Tradit Chin Med (Chin) 2005;39:53–55.
Wang QL, Li YY, Qi H, Sun XX, Zhang WJ, Jiang Y. Inotropic effects of astragaloside on heart in vitro and its possible mechanism. Chin J Chin Mater Med (Chin)1992;17:557–559.
Wu Y, Yang ZY, Zeng T. Progress in research of cardiovascular pharmacological action of astragaloside I. Shanghai Med Pharm J (Chin) 2010;31:308–310.
Qin LM, Niu FL, Xu X, Zhao LA, Qin H, Wang SR, et al. Study on the effect of Codonopsis and Astragalus in tonifying Xin-qi. Pharmacol Clin Chin Mater Med (Chin) 1987;3:31–33.
Bao XN. Treatment of Astragalus injection in elderly patients with congestive heart failure. Pharmacol Clin Chin Mater Med (Chin) 1999;15:39–40.
Lei CL, Wang XM, Jiang Y, Sun CW. Effects of astragalus saponins on single calcium channel activities. J Norman Bethune Univ (Med Sci, Chin) 1994;20:535–537.
Su YW, Zhang JZ. Effect of Astragalus Membranaceus on intracellular Ca2+ overload of cultured rat cardiomycytes during norephinephrine. J Clin Cardiol (Chin) 2004;20:549–550.
Zhang J, Shi MW, Wang DM, Li YZ, Wang LX. Influence of Astragalus Membranaceus on L-type calcium current of myocytes in rabbits with acute myocardial infarction. Chin Pharm J (Chin) 2007;42:233–234.
Qi SY, Liu KS, Wang XG, Zhang TJ, Liu XY. Effects of Astragale on calcium current of myocytes from rabbit infarcted heart. Pharm Clin Chin Mater Med (Chin) 2003;19:16–17.
Chen XJ, Meng D, Feng L, Bian YY, Li P, Yang D, et al. Protective effect of astragalosides on myocardial injury by isoproterenol in SD rats. Am J Chin Med 2006;34:1015–1025.
Li ZP, Cao Q. Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats. Acta Pharmacol Sin 2002;23:898–904.
Meng D, Chen XJ, Bian YY, Li P, Yang D, Zhang JN, et al. Effect of astragalosides on intracellular calcium overload in cardiac myocytes of neonatal rats. Am J Chin Med 2005;33:11–20.
Shi GG, Chen JX, Li CC, Liu XP. Study of effect of Astragalus Injection on coronary artery. Tradit Chin Drug Res Clin Pharmacol (Chin) 1999;10:38–39.
Chen Y, Ning XF, Cao JH, Li ZP. Effects of astragaloside IV on collagen of myocardial fibroblasts in rats. J Appl Clin Pediatr 2007;22:553–558.
Lin Y, Ning XF, Yu W, Li ZP. Effects of astragaloside IV on cardiac collagen content in rats with acute myocardial infarction and its mechanisms. Chin Pharm J (Chin) 2008;43:833–837.
Zhang ZC, Li SJ, Yang YZ, Chen RZ, Chen YZ. Effect of astragaloside on myocardial fibrosis in chronic myocarditis. Chin J Integr Tradit West Med (Chin) 2007;27:728–730.
Xu XL, Ji H, Gu SY, Huang QJ, Chen YP. Effects of astragaloside IV on experimental ventricular remodeling in mice and its mechanism from matrix metalloproteinase aspect. J China Pharm Univ (Chin) 2010;41:70–75.
Lu S. Study on protective effect of Chinese herbal medicine on myocardial damage by calcium overload. Chin J Integr Med Cardio-/Cerebrobvasc Dis (Chin) 2005;3:42–43.
Lu S, Zhang JN, Yang D, Xu JD, Chen XJ, Fang WW, et al. Effects of astragaloside in treating myocardial injury and myocardial sarco/endoplasmic Ca2+-ATPase of viral myocarditis mice. Chin J Integr Tradit West Med (Chin) 1999;19:672–674.
Meng D, Chen XJ, Yang D, Bian YY, Li P, Zhang JN. Effects of astragalosides on the cultivation of calcium overload in rat cardiac myocytes. Chin J Clin Rehabil (Chin) 2004,8:462–463.
Ikeda Y, Hoshijima M, Chien KR. Toward biologically targeted therapy of calcium cycling defects in heart failure. Physiology 2008;23:6–16.
Xu XL, Ji H, Gu SY, Shao Q, Huang QJ, Cheng YP. Modification of alterations in cardiac function and sarcoplsmic reticulum by astragaloside IV in myocardial injury in vivo. Eur J Pharm 2007;568:203–212.
Chen LX, Liao JZ, Guo WQ, Yu WJ, Qin LM. Effects of membranaceus Astragalus on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action. Chin J Integr Tradit West Med (Chin) 1995;15:141–143.
McMurray J, McLay J, Chopra M, Bridges A, Belch JJ. Evidence for enhanced free radical activity in chronic congestive failure secondary to coronary heart disease. Am J Cardiol 1990;65:1261–1262.
Li Q, Liu H. Pharmacology and clinical application of Astragalus. Med Recapitul (Chin) 2004;10:634–636.
Zhang Z, Chen LX, Qin LM, Jin B. Effects of astragaloside on hemodynamics and oxygen free radical in rats with myocardial ischemia reperfusion. Chin J Inf Tradit Chin Med (Chin) 2000;7:7–8.
Li SQ, He H. Effects of Astragalus Membranaceus on superoxide dimutase and lipid peroxide in patients with pectoris. Chin J Integr Med Cardio-/Cerebrovasc Dis (Chin) 2003;1:231–1234.
Li L, Ke L, Peng DF, Gu Y. The effect of astragalus memberanaceus on the myocardium during anoxia. Chin J Integr Med Cardio-/Cerebrovasc Dis (Chin) 2003;1:79–80.
Narula J, Pandey P, Arbustini E, Haider N, Narula N, Kolodgie FD, et al. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci USA 1999;96:8144–8149.
Feng JP, Lu Y, Zhao BR, Yao Z, Liang BP, Liang SL. The inhibitory effect of Astragalus Membranaceus on the apoptosis induced by myocardial ischemia reperfusion. J Integr Tradit Chin West Med Pract Crit Care Med (Chin) 2001;3:13–15.
Peng DF, Ke L, Li L, Zeng K, Gu Y. The protection of Astragalus memberanaceus against hypoxia cardiomyocyte. J Clin Cardiol (Chin) 2003;19:234–236.
Li L, Tao HY, Chen JB, Deng H, Lv JH, Li SJ. Anti-apoptosis effect of astragaloside on adriamycin induced rat’s cardiotoxicity. Chin J Integr Tradit West Med (Chin) 2006;26:1011–1014.
Zhong F, Du JZ, Yu XH, Zhang ZC, Chen RZ, Li SJ. Effect of astragaloside on apoptosis in viral myocarditis. J Nanhua Univ (Med Edition, Chin) 2004;32:17–19.
Liu JM, Shen CL, Zhao HB. Clinical study on the intervention action of Jianxin Decoction on the serum cytokine level with congestive heart failure. J Emerg Tradit Chin Med (Chin) 2004;13:5–6.
Song HM, Luo M, Deng B. The effect of various doses of perindopril on the plasma levels of ET and NO in patients with chronic heart failure. Chin Heart J (Chin) 2005;17:46–48.
Yao J, Qian SM, Huang J. Influence of Xinlishu Naristillae on the level of neuroendocrine cytokines in chronic heart failure rats. Chin J Integr Med Cardio-/Cerebrovasc Dis (Chin) 2003;1:316–318.
Huang YS, Xian SX, Zhou ML, Yang H, Chen ZX. Effect of Yang Xin Kang on plasma endothelin and calcitonin-gene related peptide levels in rats with myocardial hypertrophy heart failure. J Guangzhou Univ Tradit Chin Med (Chin) 2002;19:40–43.
Ma L, Liu JG, Chen KJ, Shi DZ, Xue Q, Li Y, et al. Effects of Shenqi Fuxin Oral Liquid on plasma kaliuretic peptide, myocardial contractility and relaxation of left ventricle and left ventricular remodeling in experimental rats with heart failure after myocardial infarction. Chin Pharm J (Chin) 2005;40:1629–1632.
Chen J, Yang HS, Yang W. Influence of warming-yang, dredging dampness, supplement qi and activating blood principle on heart function, endothelin and tumor necrosis factor in heart failure rats. Acta Chin Med Pharmacol (Chin) 2004;32:49–51.
He JR, Ma DJ. Study of mechanism of Astragalus injection on congestive heart failure. Shanghai Med Pharm J (Chin) 2000;21:25–26.
Liu XC, Zhang YZ, Huang ZW. Effects of irbesartan on TNF-α, endothelin-1, aldosterone and sex hormones in male patients with chronic heart failure. J Zhengzhou Univ (Med Sci, Chin) 2006;41:33–335.
Song W, Lu X, Feng Q. Tumour necrosis factor induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocyte. Cardiovasc Res 2000;45:595–602.
Tang ZX, Li YF, Hong XZ, Chen WF, Liu B. Astragalus for heart failure and its influence on tumor necrosis factor. China Pharm (Chin) 2001;12:98–99.
Yang QY, Lu S, Sun HR. Effects of Astragalus on cardiac function and serum tumor necrosis factor-α level in patients with chronic heart failure. Chin J Integr Tradit West Med (Chin) 2010;30:699–701.
Ma L, Liu J, Chu N, Yang JG, Shi XB, Wang YJ, et al. The relationship between cardiac hypertrophy index and cardiac function in chronic heart failure rats. J Capit Med Univ (Chin) 2010;31:596–599.
Hong Y, Xu SZ, Zeng DY, Hou JY. Study of the inhibitory effect of Huangqi Injection on experimental cardiac hypertrophy in rats. Chin Tradit Patent Med (Chin) 2002;24:525–529.
Luo XP, Shi HM, Zeng ZY, Fan WH, Dai RH. The effect of Huang Qi injection on cardiac function and left ventricular collagen remodeling after myocardial infaction in rats. Chin J Pathophysiol (Chin) 1999;15:639–642.
Zhang JG, Gao DS, Wei GH, Shen CY, Wang SC, Liu YJ, et al. Clinical study on effect of astragalus lnjection on left ventricular remodeling and left ventricular function in patients with acute myocardial infarction. Chin J Integr Tradit West Med (Chin) 2002;22:346–349.
Zheng SZ, Zhou HB, Wang TY, Shao YN. Preliminary study on effect of Astragalus on β receptor of cardiac cells in mouse. Acta Acad Med Nanjing (Chin) 1997;17:78–79.
Shi RR, Liu YH, He LM, Zhao SL, Weng SA, Yi NY. The regulatory function of Astragalus membranaceus on brain m-receptor and heart p-adrenoeceptor of aged rats. Chin J Tradit Med Sci Technol (Chin) 1998;5:27–30.
Zhang BQ, Sun J, Hu SJ, Shan YX, Xia Q. Astragalus membranaceus induced endothelium-dependent vasomotor effect and its mechanism in rat thoracic aortas. Chin J Pharmacol Toxicol (Chin) 2005;19:44–48.
Zhang WD, Zhang C, Wang XH, Gao PJ, Zhu DL, Chen H, et al. Astragaloside IV dilates aortic vessels from normal and spontaneously hypertensive rats through endothelium-dependent and endothelium-independent ways. Planta Med 2006;72:621–626.
Zhang WD, Chen H, Zhang C, Liu RH, Li HL, Chen HZ. Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med 2006;72:4–8.
Zhang C, Wang XH, Zhong MF, Liu RH, Li HL, Zhang WD, et al. Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings. Clin Exp Pharmacol Physiol 2007;34:387–392.
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