Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine

Yi-yang Hu

doi:10.1007/s11655-012-1029-7

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Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine

OriginalPaper | Updated：2021-08-27

- Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine
- Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine
- 中国结合医学杂志（英文版） 2012年18卷第8期页码：563-564
- Affiliations：
  
  Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Institute of Liver Diseases, Shanghai University of Chinese medicine,Shanghai,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-012-1029-7
  中图分类号：
- 纸质出版日期：2012，
  
  网络出版日期：2012-3-21，
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Hu, Yy. Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine., Chin. J. Integr. Med. 18, 563–564 (2012). https://doi.org/10.1007/s11655-012-1029-7

Yi-yang Hu. Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine[J]. Chinese Journal of Integrative Medicine, 2012,18(8):563-564.
Hu, Yy. Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine., Chin. J. Integr. Med. 18, 563–564 (2012). https://doi.org/10.1007/s11655-012-1029-7 DOI：

Yi-yang Hu. Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine[J]. Chinese Journal of Integrative Medicine, 2012,18(8):563-564. DOI： 10.1007/s11655-012-1029-7.

摘要

In this review

the researches on Chinese herb components with anti-hepatic fibrosis activity in China in the recent 20 years were generalized. Almost thirty active herb components attracted author’s attention

especially

salvianolic acid B and oxymatrine which were investigated comprehensively. Moreover

the author considered that

in view of the complex pathogenesis and the multi-pathway and multi-target superiority of Chinese medicine formula

the effective components formula investigations deserve more attention and probably prompt a potential researching direction.

Abstract

In this review

the researches on Chinese herb components with anti-hepatic fibrosis activity in China in the recent 20 years were generalized. Almost thirty active herb components attracted author’s attention

especially

salvianolic acid B and oxymatrine which were investigated comprehensively. Moreover

the author considered that

in view of the complex pathogenesis and the multi-pathway and multi-target superiority of Chinese medicine formula

the effective components formula investigations deserve more attention and probably prompt a potential researching direction.

关键词

Liver FibrosisChinese Materia Medicaactive component

Keywords

Liver FibrosisChinese Materia Medicaactive component

references

Li XM, Li HS, Hu YY. Research progress of anti-liver fibrosis herbal ingredients or constituents. Chin J Integr Tradit West Med Liver Dis (Chin) 2008;18:186–189.

Liu P, Hu YY, Liu C, Zhu DY, Xue HM, Xu ZQ, et al. Clinical observation of salvianolic acid B in treatment of liver fibrosis in chronic hepatitis B. World J Gastroenterol 2002;8:679–685.

Hu YY, Liu P, Liu C, Gu HT, Xu LM, Liu CH, et al. Influence of the extract of Radix Salviae Miltiorrhizae on hepatic fibrosis induced by CCl4 and DMN in rats. Shanghai J Tradit Chin Med (Chin) 1999;33:7–10.

Liu CH, Liu P, Hu YY, Zhu DY. Effects of salvianolic acid-B on TGF-β1 stimulated hepatic stellate cell activation and its intracellular signaling. Natl Med J China (Chin) 2002;82:1267–1272.

Tao YY, Wang XL, Liu CH. Salvianolic acid-B effects on TGF-β1/ERK signaling transduction in NIH/3T3 fibroblast. J Capit Med Univ (Chin) 2007;28:192–195.

Mao YM, Zeng MD, Lu LG, Li JQ, Wan MB, Li CZ, et al. Oxymatrine capsule in the treatment of liver fibrosis in patients with chronic virus hepatitis: a randomized, double blind, placebo-controlled, multicenter clinical study (II). Chin Hepatol (Chin) 2002;4:222–225.

Zen WZ, Wu XL, Jiang MD. Effect of oxymarine on Smad gene expression in CCl4-induced hepatic fibrosis in rats. World J Dig (Chin) 2005;13:984–987.

Song J, Wang LL, Zhu L, Zhong HM, Yao P. Effects of oxymatrine on procollagen III metabolism and its gene expression in experimental fibrotic rats. Chin J Hepatol (Chin) 2003;11:697.

Lu Q, Zhang QB, Zhang JM, Yin YK, Wu XH. The inhibition effect of oxymatrine on the activation of paracrine pathway of hepatic stellate cells. Chin Hepatol (Chin) 2004;9:31–33.

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