FOLLOWUS
1. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
2. Qilu Hospital of Shandong University,Jinan,China
3. Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
4. Shandong University of Traditional Chinese Medicine,Jinan,China
纸质出版日期:2012,
网络出版日期:2012-8-31,
Scan for full text
Liu, Lt., Guo, G., Wu, M. et al. The progress of the research on cardio-vascular effects and acting mechanism of polydatin., Chin. J. Integr. Med. 18, 714–719 (2012). https://doi.org/10.1007/s11655-012-1060-8
Long-tao Liu, Gang Guo, Min Wu, et al. The progress of the research on cardio-vascular effects and acting mechanism of polydatin[J]. Chinese Journal of Integrative Medicine, 2012,18(9):714-719.
Liu, Lt., Guo, G., Wu, M. et al. The progress of the research on cardio-vascular effects and acting mechanism of polydatin., Chin. J. Integr. Med. 18, 714–719 (2012). https://doi.org/10.1007/s11655-012-1060-8 DOI:
Long-tao Liu, Gang Guo, Min Wu, et al. The progress of the research on cardio-vascular effects and acting mechanism of polydatin[J]. Chinese Journal of Integrative Medicine, 2012,18(9):714-719. DOI: 10.1007/s11655-012-1060-8.
Rhizoma Polygoni Cuspidati
a Chinese herbal drug
has actions of dispelling dampness
alleviating jaundice
clearing heat
subsiding toxin
activating blood
and removing stasis. Polydatin (PD)
one of its chief active ingredients
has been proved by modern pharmacological studies to possess extensive cardiovascular pharmacological activity
showing marked effects on protecting cardio-myocyte
dilating blood vessel
antagonizing platelet aggregation
thrombosis
and atherosclerosis. The progress of the research on cardiovascular pharmacological actions and the acting mechanism of PD was reviewed in this paper.
Rhizoma Polygoni Cuspidati
a Chinese herbal drug
has actions of dispelling dampness
alleviating jaundice
clearing heat
subsiding toxin
activating blood
and removing stasis. Polydatin (PD)
one of its chief active ingredients
has been proved by modern pharmacological studies to possess extensive cardiovascular pharmacological activity
showing marked effects on protecting cardio-myocyte
dilating blood vessel
antagonizing platelet aggregation
thrombosis
and atherosclerosis. The progress of the research on cardiovascular pharmacological actions and the acting mechanism of PD was reviewed in this paper.
polydatincardio-vascular systempharmacological actionmechanism studyreview
polydatincardio-vascular systempharmacological actionmechanism studyreview
Kong XH, Zhou LZ. Study progress of giant knotweed rhizome. Guiding J Tradit Chin Med Pharm (Chin) 2009;15(5):107–110.
Gao SH, Yang SL, Fan GR. Study progress of polydatin. J Pharmaceutical Practice (Chin) 2005;23(5):145–147.
Das S, Das DK. Resveratrol: a therapeutic promise for cardiovascular diseases. Recent Pat Cardiovasc Drug Discov 2007;2:133–138.
Zhang LP, Yang CY, Wang YP, Guan Y, Xu Y, Zhang Y. ATP-sensitive potassium channel and mitochondrial permeability transition pore involve in cardioprotection of polydatin. Chin J Pharm Toxicol (Chin) 2009;32:81–88.
Zhao J, Li HY, Wang ZH, Tong CQ. Effect of polydatin on ultrastructure of cardiac myocytes in rats with adriamycin-induced myocardial damage. Acta Acad Med CPAPF (Chin) 2010;19:629–630,shift 634.
Zhang DQ, Sun LS, Xu JP. Effect of piceid on the dog with an acute myocardial infarction model. Herald Med (Chin) 2006;25:510–513.
Zhao Q, Huang HX, Jin CH. The regulation and its mechanism of polydatin on the β-adrenoreceptor in cardiac myocytes stimulated by lipopolysaccharide. Chin Pharm Bull (Chin) 2004;20:769–772.
Xue X, Jin CH, Li L, Xiang J. Influence of polydatin on myocardial function and ultrastructure of LPS infected rats. China Practical Med (Chin) 2008;3(33):3–4.
Gao JP, Chen CX, Gu WL, et al. Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models. Fitoterapia 2010;81:953–960.
Huang QB, Zhao KS, Huang XL. Effects of crytal No4 of polygonum cuspidatum, dopamine and 645-2 on hemorrhagic shock in rats. Chin J Microcirc (Chin) 1995;5(1):7–9.
Liu J, Jin CH, Zhao KS. Effects of polydatin on ATP sensitive potassium channels of arteriolar smooth muscle cells. Chin J Microcirc (Chin) 1999;9(4):7–9.
Jin CH, Zhao KS. The regulat ion of polydat in on intracellular free calcium and membrane potential of human vascular smooth muscle cells. Chin J Pathophysiol (Chin) 1999;15:233–236.
Wang YG, Jin CH, Huang HX, Zhao Q, Wu SP. Effect of PD on the activity of protein kinase C of vascular smooth muscle cells. Chin Pharm Bull (Chin) 2005;2:461–464.
Wang YG, Jin CH, Huang HX, Wu PS. Effect of polydatin on the activity of protein kinase C of VSMC treated by LPS and sera of burned rats. J Fourth Military Med Univ (Chin) 2006;27:1960–1962.
Wang Y, Xue J, Sun XD, Yuan BX, Deng XL, Yu XJ. Study on decreasing effects of polydatin on blood viscosity in the rat model of acute blood stasis. China Pharm 2004;15:275–277.
Chen P, Yang LC, Lei WY, Shen ZQ, Wang DH. Investigation on antithrombotic effects of polydatin. J Kunming Med Coll (Chin) 2006;27(1):10–12.
Chen P, Hu XL, Lei WY, Shen ZQ. Effects of polydatin on thrombosis and interactions of platelets to neutrophils. J Yunnan Univ (Natural Sci, Chin) 2006;28(4):364–368.
Chen P, Yang LC, Hu XL, Lei WY, Shen ZQ. Investigation of polydatin on antithrombotic effects and plasma levels of TXB2 and 6-keto-PGF1α. Nat Prod Res Dev (Chin) 2006;18:398–400, shift 404.
Zhu LX, Jin ZY. Effect of polydatin on metabolism of blood lipid of hyperlipidemia rats and its antioxidation. Chin Tradit Patent Med (Chin) 2006;28:260–261.
Du J, Sun LN, Xing WW, et al. Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters. Phytomedicine 2009;16:652–658.
Xing WW, Wu JZ, Jia M, Du J, Zhang H, Qin LP. Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits. Biomed Pharmacother 2009;63:457–462.
Qin J, Chen YZ, Zhou QX, Shi RF, Jiang QS, Lou Q. Effect of polydatin on endothelial function in aorta vascular strips of healthy rabbits treated with ADMA. Chin Tradit Herbal Drugs (Chin) 2004;35:535–538.
Zhu LX, Jin ZY. Effects of piceid on blood lipid metabolism, nitric oxide and nitricoxide synthase in experimental hyperlipidemia rats. Pharm Clin Chin Materia Med (Chin) 2005;21(3):16–18.
Xu FQ, Xu H, Liu JG, Chen KJ. Effects of Xiongshao Capsule on the proliferation of vascular smooth muscle cells in rabbits with atherosclerosis. Chin J Integr Tradit West Med (Chin) 2008;28:912–916.
Zhou XM, Zhou DX, Liu Y, Hong L. Progress research on regulating vascular smooth muscle cell proliferation by TCM intervention. Chin J Modern Drug Application (Chin) 2010;4:224–225.
Zhou ZM, Feng YB, Zhou YJ. Effect of resveratrol on the proliferation of cultured vascular smooth muscle cells. Chin J Geriatric Cardiovasc Cerebrovasc Dis (Chin) 2004;6:335–337.
Wang QQ, Jiao JJ, Li WH, Qu Q. Effects of resveratrol on the proliferation and CaN of vascular smooth muscle cell induced by angiotensin II. Chin J of Appl Physiol (Chin) 2009;25:334–337.
Poussier B, Cordova AC, Becquemin JP, Sumpio BE. Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis. J Vascular Surg 2005;42:1190–1197.
Konishi A, Aigawa T, Mohan A, Korshunov VA, Berk BC. Hydrogen peroxide activates the Gas6-Axl pathway in vascular smooth muscle cells. J Biol Chem 2004;279:28766–28770.
Su D, Zhang BL, Huan ML, Huang QJ, Zhu CL, Zhou SY. Comparison of resveratrol and polydatin on anti-oxidative activities. China Pharmacist (Chin) 2010;13:471–473.
Collot-Teixeira S, Martin J, McDermott-Roe C, Poston R, McGregor JL. CD36 and macrophages in atherosclerosis. Cardiovasc Res 2007;75:468–477.
Xiao MJ, Chen WH, Wu W, Guo W, Zhao KS, Zhao M. Polydatin inhibits lipid peroxidation induced by ox-LDL and down-regulates CD36 expression in macrophages. Chin J Pathophysiol (Chin) 2010;26:1280–1284.
Liu LT, Wu Min, Zhang WG, Zheng GJ, Yin JH, Liu MX, et al. Intervention study of polydatin on plaque stability of carotid ahterosclerosis. Beijing J Tradit Chin Med (Chin) 2009;2:172–175.
0
浏览量
75
Downloads
24
CSCD
关联资源
相关文章
相关作者
相关机构