Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients

Amirhossein Ahmadi

doi:10.1007/s11655-012-1183-y

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Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients

ReviewPaper | Updated：2021-08-27

- Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients
- Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients
- 中国结合医学杂志（英文版） 2012年18卷第8期页码：635-640
- Affiliations：
  
  Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari,Iran
- Author bio：
- Funds：
- DOI：10.1007/s11655-012-1183-y
  中图分类号：
- 纸质出版日期：2012，
  
  网络出版日期：2012-8-2，
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Ahmadi, A. Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients., Chin. J. Integr. Med. 18, 635–640 (2012). https://doi.org/10.1007/s11655-012-1183-y

Amirhossein Ahmadi. Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients[J]. Chinese Journal of Integrative Medicine, 2012,18(8):635-640.
Ahmadi, A. Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients., Chin. J. Integr. Med. 18, 635–640 (2012). https://doi.org/10.1007/s11655-012-1183-y DOI：

Amirhossein Ahmadi. Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients[J]. Chinese Journal of Integrative Medicine, 2012,18(8):635-640. DOI： 10.1007/s11655-012-1183-y.

摘要

In recent years

more head and neck cancer patients have been treated with radiotherapy. Radiation-induced mucositis is a common and dose limiting toxicity of radiotherapy among patients with head and neck cancers. Patients undergoing radiation therapy for head and neck cancer are also at increased risk of developing oral candidiasis. A number of new agents applied locally or systemically to prevent or treat radiationinduced mucositis have been investigated

but there is no widely accepted prophylactic or effective treatment for mucositis. Topical Aloe vera is widely used for mild sunburn

frostbites

and scalding burns. Studies have reported the beneficial effects of Aloe gel for wound healing

mucous membrane protection

and treatment of oral ulcers

in addition to antiinflammatory

immunomudulation

antifungal

scavenging free radicals

increasing collagen formation and inhibiting collagenase. Herein the author postulates that oral Aloe vera mouthwash may not only prevent radiation-induced mucositis by its wound healing and antiinflammatory mechanism

but also may reduce oral candidiasis of patients undergoing head and neck radiotherapy due to its antifungal and immunomodulatory properties. Hence

Aloe vera mouthwash may provide an alternative agent for treating radiation-induced oral mucositis and candidiasis in patients with head and neck cancers.

Abstract

In recent years

but there is no widely accepted prophylactic or effective treatment for mucositis. Topical Aloe vera is widely used for mild sunburn

frostbites

and scalding burns. Studies have reported the beneficial effects of Aloe gel for wound healing

mucous membrane protection

and treatment of oral ulcers

in addition to antiinflammatory

immunomudulation

antifungal

scavenging free radicals

but also may reduce oral candidiasis of patients undergoing head and neck radiotherapy due to its antifungal and immunomodulatory properties. Hence

Aloe vera mouthwash may provide an alternative agent for treating radiation-induced oral mucositis and candidiasis in patients with head and neck cancers.

关键词

Aloe veramouthwashradiotherapymucositishead and neck cancercandidiasis

Keywords

Aloe veramouthwashradiotherapymucositishead and neck cancercandidiasis

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