Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection

Youngmin Bu; Kyungjin Lee; Hyuk-Sang Jung; Sang-Kwan Moon

doi:10.1007/s11655-013-1341-2

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Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection

OriginalPaper | Updated：2021-08-27

- Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection
- Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection
- 中国结合医学杂志（英文版） 2013年19卷第11期页码：804-814
- Affiliations：
  
  1. Department of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea
  2. Department of Anatomy, College of Korean Medicine, Institute of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea
  3. Department of Cardiovascular and Neurologic Disease, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea
- Author bio：
- Funds：
  
  Supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (No. NRF-2012R1A1A2008587)
- DOI：10.1007/s11655-013-1341-2
  中图分类号：
- 纸质出版日期：2013，
  
  网络出版日期：2013-10-30，
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Bu, Y., Lee, K., Jung, HS. et al. Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection., Chin. J. Integr. Med. 19, 804–814 (2013). https://doi.org/10.1007/s11655-013-1341-2

Youngmin Bu, Kyungjin Lee, Hyuk-Sang Jung, et al. Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection[J]. Chinese Journal of Integrative Medicine, 2013,19(11):804-814.
Bu, Y., Lee, K., Jung, HS. et al. Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection., Chin. J. Integr. Med. 19, 804–814 (2013). https://doi.org/10.1007/s11655-013-1341-2 DOI：

Youngmin Bu, Kyungjin Lee, Hyuk-Sang Jung, et al. Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection[J]. Chinese Journal of Integrative Medicine, 2013,19(11):804-814. DOI： 10.1007/s11655-013-1341-2.

摘要

Although many agents for acute ischemic stroke treatment have been developed from extensive preclinical studies

most have failed in clinical trials. As a result

researchers are seeking other methods or agents based on previous studies. Among the various prospective approaches

vascular protection might be the key for development of therapeutic agents for stroke and for improvements in the efficacy and safety of conventional therapies. Traditional medicines in Asian countries are based on clinical experiences and literature accumulated over thousands of years. To date

many studies have used traditional herbal medicines to prove or develop new agents based on stroke treatments mentioned in traditional medicinal theory or other clinical data. In the current review

we describe the vascular factors related to ischemic brain damage and the herbal medicines that impact these factors

including Salviae Miltiorrhizae Radix

Notoginseng Radix

and Curcumae Rhizoma

based on scientific reports and traditional medical theory. Further

we point out the problems associated with herbal medicines in stroke research and propose better methodologies to address these problems.

Abstract

Although many agents for acute ischemic stroke treatment have been developed from extensive preclinical studies

most have failed in clinical trials. As a result

researchers are seeking other methods or agents based on previous studies. Among the various prospective approaches

many studies have used traditional herbal medicines to prove or develop new agents based on stroke treatments mentioned in traditional medicinal theory or other clinical data. In the current review

we describe the vascular factors related to ischemic brain damage and the herbal medicines that impact these factors

including Salviae Miltiorrhizae Radix

Notoginseng Radix

and Curcumae Rhizoma

based on scientific reports and traditional medical theory. Further

we point out the problems associated with herbal medicines in stroke research and propose better methodologies to address these problems.

关键词

Traditional Medicinevascular protectionischemic strokeSalviae Miltiorrhizae RadixNotoginseng RadixCurcumae Rhizoma

Keywords

Traditional Medicinevascular protectionischemic strokeSalviae Miltiorrhizae RadixNotoginseng RadixCurcumae Rhizoma

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