Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy

Xin Mou; Di-yi Zhou; Wen-hong Liu; Dan-yang Zhou; Ying-hui Liu; Yong-bin Hu; Cheng-min Shou; Jia-wei Chen; Jin-xi Zhao; Guo-ling Ma

doi:10.1007/s11655-013-1411-0

Your Location：

Home >

Browse articles >

Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy

OriginalPaper | Updated：2021-08-27

- Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy
- Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy
- 中国结合医学杂志（英文版） 2013年19卷第9期页码：656-662
- Affiliations：
  
  1. Department of Endocrinology, Hangzhou Red-Cross Hospital,Hangzhou,China
  2. Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing,China
  3. Zhejiang University of Traditional Chinese Medicine,Hangzhou,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No.30801467, No. 81273623) and the Natural Science Foundation of Zhejiang Province (No.Y2080683)
- DOI：10.1007/s11655-013-1411-0
  中图分类号：
- 纸质出版日期：2013，
  
  网络出版日期：2013-4-10，
Scan for full text
Mou, X., Zhou, Dy., Liu, Wh. et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy., Chin. J. Integr. Med. 19, 656–662 (2013). https://doi.org/10.1007/s11655-013-1411-0

Xin Mou, Di-yi Zhou, Wen-hong Liu, et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy[J]. Chinese Journal of Integrative Medicine, 2013,19(9):656-662.
Mou, X., Zhou, Dy., Liu, Wh. et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy., Chin. J. Integr. Med. 19, 656–662 (2013). https://doi.org/10.1007/s11655-013-1411-0 DOI：

Xin Mou, Di-yi Zhou, Wen-hong Liu, et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy[J]. Chinese Journal of Integrative Medicine, 2013,19(9):656-662. DOI： 10.1007/s11655-013-1411-0.

摘要

To explore the relationship between Chinese medicine (CM) constitutive susceptibility and syndrome diversity in diabetic nephropathy (DN). Epidemiologic investigation on constitution adopting the “Constitution in Chinese Medicine Questionnaire” (CCMQ)

and survey on syndrome type by CM syndrome scale (preliminary) were carried out in 180 DN patients. Cluster analysis on symptom items was used to determine the syndrome type

and canonical correlation analysis was used to analyze the relationship between patients’ constitution and syndrome. Baseline levels in all enrolled patients were not different statistically. Cluster analysis showed 8 syndromes existed in DN patients

namely: I

qi-yin deficiency with qistagnancy type; II

yin-yang deficiency with heat-water-blood stasis type; III

qi-yin deficiency with dampnessheat type; IV

yin-yang deficiency with blood-stasis and heat type; V

qi-yin deficiency with stagnant heat type; VI

yin-yang deficiency with inner dampness-heat stagnancy type; VII

yin deficiency with heat stagnancy type; and VIII

Kidney (Shen)-Spleen (Pi) deficiency with stagnant heat type. Correlation analysis on the 8 syndromes and the 9 constitutions showed statistical significant correlations between syndrome III and dampness-heat constitution (P=0.0001); syndrome IV and blood-stasis constitution (P=0.0001); and syndrome VII and yin-deficiency constitution (P=0.0180). Certain relationship revealed between CM constitutions and syndrome types; constitution decides the disease genesis

its syndrome type and prognosis

as well as the change of syndromes.

Abstract

and survey on syndrome type by CM syndrome scale (preliminary) were carried out in 180 DN patients. Cluster analysis on symptom items was used to determine the syndrome type

namely: I

qi-yin deficiency with qistagnancy type; II

yin-yang deficiency with heat-water-blood stasis type; III

qi-yin deficiency with dampnessheat type; IV

yin-yang deficiency with blood-stasis and heat type; V

qi-yin deficiency with stagnant heat type; VI

yin-yang deficiency with inner dampness-heat stagnancy type; VII

yin deficiency with heat stagnancy type; and VIII

its syndrome type and prognosis

as well as the change of syndromes.

关键词

diabetic nephropathyChinese medicine constitutionsyndromatologic study

Keywords

diabetic nephropathyChinese medicine constitutionsyndromatologic study

references

Meetoo D, McGovern P, Safadi R. An epidemiological overview of diabetes across the world. Br J Nurs 2007;16:1002–1007.

Yang WY, Lu JM, Weng JP, Jia WP, Ji LN, Xiao JZ, et al. Prevalence of diabetes among men and women in China. N Engl J Med 2010;362:1090–1101.

McDonald S, Excell L, Livingston B. Appendix II, in ANZDATA (Australia and New Zealand dialysis and transplant) registry report. Peritional Dial; 2008:499–518.

Yamagata K, Iseki K, Nittak K, Imai H, Iion Y, Matsuo S, et al. Chronic kidney disease perspectives in Japan and the importance of urinalysis screening. Clin Exp Nephrol 2008;12:1–8.

Lysaght M. Maintenance dialysis population dynamics: current trends and long term implications. J Am Soc Nephrol 2002;13:37–40.

Chinese Diabetes Society of Chinese Medical Association. China guideline for diabetes preventions and treatment. Chin J Prevent Control Chron Non-communic Dis (Chin) 2004;6:46–48.

Mogensen CE. Early diabetic renal involvelent and nephropathy. Amsterdam: Elsevier Science Publishers; 1987:306.

Wang Q, Zhu YB, Xue HS, Li S. Primary compiling of constitution in Chinese medicine questionnaire. Chin J Clin Rehabilit (Chin) 2006;10(3):20–22.

Zhu YB, Wang Q, Orikasa Q. Evaluation for reliability and validity of constitution in Chinese medicine questionnaire. Chin J Behav Med Sci (Chin) 2007;16:651.

Mou X, Zhou DY, Zhao JX. Exploration of the research method for Chinese medicine syndrome questionnaire of diabetic nephropathy. China J Tradit Chin Med Pharm (Chin) 2007;22:787.

Zhu YB, Wang Q, Xue HS, Orikasa Q. Preliminary assessment on performance of constitution in Chinese medicine questionnaire. Chin J Clin Rehabilit (Chin) 2006;10(3):15–17.

Wang Q. Three key problems in study of Chinese medicine constitution. J Tradit Chin Med (Chin) 2006;47:329.

Zhao Y, Tong XL, Chen L. Discussion on the relationship between evolvement of β cell function of type 2 diabetes and difference syndroms of TCM. Shandong J Tradit Chin Med (Chin) 2006;25(1):3–5.

Kuang DY. Several problems in study of constitution. J Beijing Univ Tradit Chin Med (Chin) 1986;9:18.

Jing H. Relationship between constitution and Chinese medicine syndrome. J Liaoning Coll Tradit Chin Med (Chin) 1992;6:18.

Song HP. Analysis on constitution and differentiation and treatment of Chinese medicine syndrome. Tradit Chin Med Res (Chin) 1998;11(4):11–14.

Chen JX. Significance of constitution in Chinese medicine diagnosis. Gansu Coll Tradit Chin Med (Chin) 1996;3(1):1.

Wang Q. Chinese medicine constitution. Beijing: China Medical Science Press; 1995:297.

FULL TEXT LINK

More>

浏览量

1023

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Association of Chinese medicine constitution susceptibility to diabetic nephropathy and transforming growth factor-β1 (T869C) gene polymorphism

Total triterpene acids, isolated from Corni Fructus, ameliorate progression of renal damage in streptozotocin-induced diabetic rats

Regulation of C-type natriuretic peptides and natriuretic peptide receptor-B expression in diabetic rats renal treated by Tongluo Recipe (通络方)

Effects of panax notoginoside on the nephropathy in rats with type 1 diabetes mellitus

Chinese Medicine for Treating Diabetic Nephropathy