Advances and challenges in screening traditional Chinese anti-aging materia medica

Chun-sheng Li; Hong-bin Deng; Dian-dong Li; Zhao-he Li

doi:10.1007/s11655-013-1432-8

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Advances and challenges in screening traditional Chinese anti-aging materia medica

OriginalPaper | Updated：2021-08-27

- Advances and challenges in screening traditional Chinese anti-aging materia medica
- Advances and challenges in screening traditional Chinese anti-aging materia medica
- 中国结合医学杂志（英文版） 2013年19卷第4期页码：243-252
- Affiliations：
  
  1. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,China
  3. Fengsheng Orthopedics Specialist Hospital,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-013-1432-8
  中图分类号：
- 纸质出版日期：2013，
  
  网络出版日期：2013-4-2，
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Li, Cs., Deng, Hb., Li, Dd. et al. Advances and challenges in screening traditional Chinese anti-aging materia medica., Chin. J. Integr. Med. 19, 243–252 (2013). https://doi.org/10.1007/s11655-013-1432-8

Chun-sheng Li, Hong-bin Deng, Dian-dong Li, et al. Advances and challenges in screening traditional Chinese anti-aging materia medica[J]. Chinese Journal of Integrative Medicine, 2013,19(4):243-252.
Li, Cs., Deng, Hb., Li, Dd. et al. Advances and challenges in screening traditional Chinese anti-aging materia medica., Chin. J. Integr. Med. 19, 243–252 (2013). https://doi.org/10.1007/s11655-013-1432-8 DOI：

Chun-sheng Li, Hong-bin Deng, Dian-dong Li, et al. Advances and challenges in screening traditional Chinese anti-aging materia medica[J]. Chinese Journal of Integrative Medicine, 2013,19(4):243-252. DOI： 10.1007/s11655-013-1432-8.

摘要

To provide a better service for senior health care

we summarized screening studies of traditional Chinese anti-aging materia medica (TCAM). We collected and analyzed literature of TCAM screening studies using the lifespan test and animal models of aging from 1984 to 2012. We found 26 screening methods for TCAM

and 153 single herbs or active ingredients of TCAM that have been screened out during the past 28 years. The cell lifespan test

the fruit fly lifespan test

and D-galactose aging model were the most widely used and intensively studied screening methods. However

the method for establishing the D-galactose aging model needs to be standardized

and the D-galactose aging model cannot completely be a substitute for the normal aging mouse model. Great success has been achieved in screening studies in TCAM. To further improve screening studies in TCAM

we suggest that the D-galactose aging model be incorporated into the lifespan test in the New Drugs of Traditional Chinese Medicine Research Guide.

Abstract

To provide a better service for senior health care

and 153 single herbs or active ingredients of TCAM that have been screened out during the past 28 years. The cell lifespan test

the fruit fly lifespan test

and D-galactose aging model were the most widely used and intensively studied screening methods. However

the method for establishing the D-galactose aging model needs to be standardized

we suggest that the D-galactose aging model be incorporated into the lifespan test in the New Drugs of Traditional Chinese Medicine Research Guide.

关键词

Chinese anti-aging materia medicalifespan testanimal model of agingscreening research

Keywords

Chinese anti-aging materia medicalifespan testanimal model of agingscreening research

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