Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model

Byung Il Yoon; Woong Jin Bae; Yong Sun Choi; Su Jin Kim; U. Syn Ha; Sung-Hoo Hong; Dong Wan Sohn; Sae Woong Kim

doi:10.1007/s11655-013-1547-y

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Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model

OriginalPaper | Updated：2021-08-27

- Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model
- Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model
- 中国结合医学杂志（英文版） 2018年24卷第8期页码：621-626
- Affiliations：
  
  1. Department of Urology, International St Mary’s Hospital, The Catholic Kwandong University of Korea, Incheon, Republic of Korea
  2. Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
- Author bio：
- Funds：
  
  Supported by the Biogreen 21 Program (No. PJ007186), Rural Development Administration, Suwon, Republic of Korea and a grant of the Traditional Korean Medicine Project, Ministry of Health and Welfare, Republic of Korea (No. F110004)
- DOI：10.1007/s11655-013-1547-y
  中图分类号：
- 纸质出版日期：2018，
  
  网络出版日期：2013-10-14，
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Yoon, B.I., Bae, W.J., Choi, Y.S. et al. Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model., Chin. J. Integr. Med. 24, 621–626 (2018). https://doi.org/10.1007/s11655-013-1547-y

Byung Il Yoon, Woong Jin Bae, Yong Sun Choi, et al. Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model[J]. Chinese Journal of Integrative Medicine, 2018,24(8):621-626.
Yoon, B.I., Bae, W.J., Choi, Y.S. et al. Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model., Chin. J. Integr. Med. 24, 621–626 (2018). https://doi.org/10.1007/s11655-013-1547-y DOI：

Byung Il Yoon, Woong Jin Bae, Yong Sun Choi, et al. Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model[J]. Chinese Journal of Integrative Medicine, 2018,24(8):621-626. DOI： 10.1007/s11655-013-1547-y.

摘要

To investigated the anti-inflammatory and antimicrobial effects of anthocyanins extracted from black soybean on the chronic bacterial prostatitis (CBP) rat model. The Sprague-Dawley rats were divided into 4 groups

including control

ciprofloxacin

anthocyanins and anthocyanins with ciprofloxacin groups (n=8 in each group). Then

drip infusion of bacterial suspension (Escherichia coli Z17 O2:K1:H−) into Sprague-Dawley rats was conducted to induce CBP. In 4 weeks

results of prostate tissue

urine culture

and histological analysis on the prostate were analyzed for each group. Results: The use of ciprofloxacin

anthocyanins

and anthocyanins with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in the reduction of prostatic inflammation compared with the control group (P<0.05). The anthocyanins with ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the ciprofloxacin group (P<0.05). These results suggest that anthocyanins may have anti-inflammatory and antimicrobial effects

as well as a synergistic effect with ciprofloxacin. Therefore

we suggest that the combination of anthocyanins and ciprofloxacin may be effective in treating CBP to obtain a higher rate of treatment success.

Abstract

including control

ciprofloxacin

anthocyanins and anthocyanins with ciprofloxacin groups (n=8 in each group). Then

drip infusion of bacterial suspension (Escherichia coli Z17 O2:K1:H−) into Sprague-Dawley rats was conducted to induce CBP. In 4 weeks

results of prostate tissue

urine culture

and histological analysis on the prostate were analyzed for each group. Results: The use of ciprofloxacin

anthocyanins

as well as a synergistic effect with ciprofloxacin. Therefore

we suggest that the combination of anthocyanins and ciprofloxacin may be effective in treating CBP to obtain a higher rate of treatment success.

关键词

Prostatitisanti-bacterial agentsanthocyanins

Keywords

Prostatitisanti-bacterial agentsanthocyanins

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