Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine

Xiao-feng Zhai; Cui-xia Qiao; Qun Liu; Zhe Chen; Chang-quan Ling

doi:10.1007/s11655-013-1555-y

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Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine

OriginalPaper | Updated：2021-08-27

- Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine
- Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine
- 中国结合医学杂志（英文版） 2014年20卷第11期页码：870-875
- Affiliations：
  
  1. Department of Traditional Chinese Medicine, Changhai Hospital, the Second Military Medical University,Shanghai,China
  2. Shanghai University of Traditional Chinese Medicine,Shanghai,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-013-1555-y
  中图分类号：
- 纸质出版日期：2014，
  
  网络出版日期：2013-8-13，
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Zhai, Xf., Qiao, Cx., Liu, Q. et al. Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine., Chin. J. Integr. Med. 20, 870–875 (2014). https://doi.org/10.1007/s11655-013-1555-y

Xiao-feng Zhai, Cui-xia Qiao, Qun Liu, et al. Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine[J]. Chinese Journal of Integrative Medicine, 2014,20(11):870-875.
Zhai, Xf., Qiao, Cx., Liu, Q. et al. Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine., Chin. J. Integr. Med. 20, 870–875 (2014). https://doi.org/10.1007/s11655-013-1555-y DOI：

Xiao-feng Zhai, Cui-xia Qiao, Qun Liu, et al. Quality assessment of clinical research on liver cancer treated by intra-arterial infusion of Chinese medicine[J]. Chinese Journal of Integrative Medicine, 2014,20(11):870-875. DOI： 10.1007/s11655-013-1555-y.

摘要

To assess the methodological quality of clinical research on Chinese medicine (CM) applied by intra-arterial infusion in treating primary liver cancer (PLC). Cochrane Central Register of Controlled Trials (CENTRAL)

PubMed

and three Chinese databases

including Chinese BioMedical Database (CBM)

China National Knowledge Infrastructure (CNKI) and China Academic Journal (VIP) were searched. Chinese articles were also searched manually in 16 journals. Two reviewers independently selected studies

the quality of literatures were assessed according to the Cochrane Collaboration method of quality assessment. A total of 14 articles met the inclusion criteria for this review. Only three of these articles described the randomization method used. None of the studies was blinded. All of the articles didn’t report the calculation of the sample size. Only six studies mentioned adverse reactions. All of the studies were of grade C according to the Cochrane Collaboration method. Six studies reported results of survival

and only two of these reported better efficacy in the treatment groups. The quality of studies concerned intra-arterial infusion of CM in treating with PLC was poor and the exact effect of these medicines still need evaluation. Well designed RCTs with large sample sizes

adequate follow-up data and reliable methods of assessment are needed to better appraise the real effect of CMs in the treatment of PLC patients.

Abstract

PubMed

and three Chinese databases

including Chinese BioMedical Database (CBM)

adequate follow-up data and reliable methods of assessment are needed to better appraise the real effect of CMs in the treatment of PLC patients.

关键词

primary liver cancerChinese Medicineintra-arterial infusionquality assessment

Keywords

primary liver cancerChinese Medicineintra-arterial infusionquality assessment

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