Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients

Jing-feng Liu; Meng-ya Zhao; Hai-zhou Zhuang; Chong Liu; Yi-bing Weng; Ang Li; Shu-wen Zhang; Mei-li Duan

doi:10.1007/s11655-013-1592-6

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Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients

OriginalPaper | Updated：2021-08-27

- Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients
- Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients
- 中国结合医学杂志（英文版） 2013年19卷第10期页码：730-735
- Affiliations：
  
  Department of Critical Care Medicine, Beijing Friendship Hospital Affiliated to Capital Medical University,Beijing,China
- Author bio：
- Funds：
  
  Supported by the Fund of Medicine Development in Beijing (No. SF-2009-II-14)
- DOI：10.1007/s11655-013-1592-6
  中图分类号：
- 纸质出版日期：2013，
  
  网络出版日期：2013-8-23，
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Liu, Jf., Zhao, My., Zhuang, Hz. et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients., Chin. J. Integr. Med. 19, 730–735 (2013). https://doi.org/10.1007/s11655-013-1592-6

Jing-feng Liu, Meng-ya Zhao, Hai-zhou Zhuang, et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients[J]. Chinese Journal of Integrative Medicine, 2013,19(10):730-735.
Liu, Jf., Zhao, My., Zhuang, Hz. et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients., Chin. J. Integr. Med. 19, 730–735 (2013). https://doi.org/10.1007/s11655-013-1592-6 DOI：

Jing-feng Liu, Meng-ya Zhao, Hai-zhou Zhuang, et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients[J]. Chinese Journal of Integrative Medicine, 2013,19(10):730-735. DOI： 10.1007/s11655-013-1592-6.

摘要

To investigate the correlation between different Chinese medicine (CM) syndromes and variations in microcirculation in septic shock patients. seventy Septic shock patients were divided into four groups: heat damaging qi-yin group (HDQY

23 cases); yin exhaustion and yang collapse group (YEYC

26 cases); excessive heat in Fu organ group (EHFO

10 cases); and heat damaging nutrient-blood group (HDNB

11 cases). Sublingual microcirculation parameters were observed by sidestream dark-field (SDF) imaging and scored by Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA)

and parameters of microcirculation perfusion variations and prognoses were analyzed. Compared with those with qi-yin heat damage

perfused vessel density (PVD) in other groups decreased dramatically (P<0.05)

and APACHE II scores increased significantly (P<0.05). In addition

the recovery time was prolonged substantially (P<0.05)

and the mixed venous oxygen saturation (SVO2) decreased (P<0.05). Blood lactic acid increased significantly (P<0.05)

and the mixed SVO decreased (P<0.05)

in the YEYC group. Compared with the thermal injury camp blood group

sublingual microcirculation parameter variations showed no obvious difference in the YEYC and EHFO groups (P>0.05). There were significant positive correlations between CM syndromes and APACHE II scoring in different groups (r=0.512

P<0.05). There were negative correlations between PVD and APACHE II scoring (r=−0.378

P=0.043)

the proportion of perfused vessels (PPV) and APACHE II scoring (r=−0.472

P=0.008)

as well as between the microvascular flow index (MFI) and APACHE II scoring (r=−0.424

P=0.023) in different patients. Sublingual microcirculation may serve as a clinical diagnostic parameter of the patient condition

as well as being a prognostic indicator.

Abstract

23 cases); yin exhaustion and yang collapse group (YEYC

26 cases); excessive heat in Fu organ group (EHFO

10 cases); and heat damaging nutrient-blood group (HDNB

and parameters of microcirculation perfusion variations and prognoses were analyzed. Compared with those with qi-yin heat damage

perfused vessel density (PVD) in other groups decreased dramatically (P<0.05)

and APACHE II scores increased significantly (P<0.05). In addition

the recovery time was prolonged substantially (P<0.05)

and the mixed venous oxygen saturation (SVO2) decreased (P<0.05). Blood lactic acid increased significantly (P<0.05)

and the mixed SVO decreased (P<0.05)

in the YEYC group. Compared with the thermal injury camp blood group

P<0.05). There were negative correlations between PVD and APACHE II scoring (r=−0.378

P=0.043)

the proportion of perfused vessels (PPV) and APACHE II scoring (r=−0.472

P=0.008)

as well as between the microvascular flow index (MFI) and APACHE II scoring (r=−0.424

P=0.023) in different patients. Sublingual microcirculation may serve as a clinical diagnostic parameter of the patient condition

as well as being a prognostic indicator.

关键词

septic shocksublingual microcirculationChinese medicine syndromes

Keywords

septic shocksublingual microcirculationChinese medicine syndromes

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