Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer
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OriginalPaper|Updated:2021-08-27
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Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer
Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer
中国结合医学杂志(英文版)2014年20卷第6期 页码:416-419
Affiliations:
1. National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital,Tianjin,China
2. Tianjin Medical University,Tianjin,China
Author bio:
Funds:
Supported by the National Natural Science Foundation of China (No. 81173376) and New Century Excellent Talent (NCET-11-1068)
Cao, R., Wang, Lp., Chi, Jd. et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer., Chin. J. Integr. Med. 20, 416–419 (2014). https://doi.org/10.1007/s11655-014-1681-1
Rui Cao, Li-ping Wang, Jia-dong Chi, et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer[J]. Chinese Journal of Integrative Medicine, 2014,20(6):416-419.
Cao, R., Wang, Lp., Chi, Jd. et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer., Chin. J. Integr. Med. 20, 416–419 (2014). https://doi.org/10.1007/s11655-014-1681-1DOI:
Rui Cao, Li-ping Wang, Jia-dong Chi, et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer[J]. Chinese Journal of Integrative Medicine, 2014,20(6):416-419. DOI: 10.1007/s11655-014-1681-1.
Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer
摘要
To determine whether the nodule and eminence on the frenulum labii superioris
location of Yinjiao (DU28) according to the meridian theory
could be used to prognosticate the recurrence of patients with colorectal cancer. The data of 101 patients with colorectal cancer in Tianjin Medical University Cancer Institute and Hospital from May 2011 to November 2011 was analyzed. The photos of all patients’ frenulum labii superioris were taken. Nodule and eminence on frenulum labii superioris were the positive standard. Biopsy and pathological testing for the nodule were carried out on one patient with large nodule on frenulum labii superioris. Patients with positive frenulum labii superioris had a higher risk of recurrence and/or metastasis than patients with negative frenulum labii superioris. There were no significant differences in diagnosis of recurrence and/or metastasis between the status of frenulum labii superioris and the traditional diagnostic criteria (P =0.238). The Kappa was 0.606 (P <0.001). The sensitivity was 76.0% and the specificity was 85.4%. The pathological report demonstrated that the nodule on frenulum labii superioris was mucosal excrescence with normal structure. Nodule and eminence on frenulum labii superioris are potential diagnostic markers for metastatic colorectal cancer.
Abstract
To determine whether the nodule and eminence on the frenulum labii superioris
location of Yinjiao (DU28) according to the meridian theory
could be used to prognosticate the recurrence of patients with colorectal cancer. The data of 101 patients with colorectal cancer in Tianjin Medical University Cancer Institute and Hospital from May 2011 to November 2011 was analyzed. The photos of all patients’ frenulum labii superioris were taken. Nodule and eminence on frenulum labii superioris were the positive standard. Biopsy and pathological testing for the nodule were carried out on one patient with large nodule on frenulum labii superioris. Patients with positive frenulum labii superioris had a higher risk of recurrence and/or metastasis than patients with negative frenulum labii superioris. There were no significant differences in diagnosis of recurrence and/or metastasis between the status of frenulum labii superioris and the traditional diagnostic criteria (P =0.238). The Kappa was 0.606 (P <0.001). The sensitivity was 76.0% and the specificity was 85.4%. The pathological report demonstrated that the nodule on frenulum labii superioris was mucosal excrescence with normal structure. Nodule and eminence on frenulum labii superioris are potential diagnostic markers for metastatic colorectal cancer.
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Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University
National Clinical Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital
Department of Medical Oncology, Tianjin Medical Universty General Hospital
Zhong-Shan-Men In-patient Department, Tianjin Medical University Cancer Institute and Hospital
Department of Chemistry, University of South Florida