Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations

Chi Zhang; Miao Jiang; Xiao-juan He; Ai-ping Lu

doi:10.1007/s11655-015-2041-5

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Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations

OriginalPaper | Updated：2021-08-27

- Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations
- Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations
- 中国结合医学杂志（英文版） 2015年21卷第6期页码：403-407
- Affiliations：
  
  1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences,Beijing,China
  2. Hong Kong Institute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University,Hong Kong SAR,China
- Author bio：
- Funds：
  
  Supported by China Academy of Chinese Medical Sciences Project (No. Z0218, Z0252, Z0293)
- DOI：10.1007/s11655-015-2041-5
  中图分类号：
- 纸质出版日期：2015，
  
  网络出版日期：2015-6-11，
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Zhang, C., Jiang, M., He, Xj. et al. Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations., Chin. J. Integr. Med. 21, 403–407 (2015). https://doi.org/10.1007/s11655-015-2041-5

Chi Zhang, Miao Jiang, Xiao-juan He, et al. Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations[J]. Chinese Journal of Integrative Medicine, 2015,21(6):403-407.
Zhang, C., Jiang, M., He, Xj. et al. Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations., Chin. J. Integr. Med. 21, 403–407 (2015). https://doi.org/10.1007/s11655-015-2041-5 DOI：

Chi Zhang, Miao Jiang, Xiao-juan He, et al. Clinical trials of integrative medicine for rheumatoid arthritis: Issues and recommendations[J]. Chinese Journal of Integrative Medicine, 2015,21(6):403-407. DOI： 10.1007/s11655-015-2041-5.

摘要

Controlled clinical trials of integrative therapies available to patients with rheumatoid arthritis (RA) improved dramatically in the past 20 years

largely because of the growing need and the methodologies improvement. Tripterygium wilfordii Hook. F.

a typical example of popular use herb

has been extensively studied in trials. However

clear and convincing evidence of integrative therapy

effectiveness and safety

remains insufficient to make decision. Many research efforts are hampered by standing problems with ‘syndrome’ recruitment failure. In addition

the outcome multiplicity induces the findings inefficiency to generalize to RA patients at large. Development of validated syndrome outcomes and methodologies has also been critical. Current efforts to enhance the understanding of integrative treatment options for patients with RA include the development of drug-specific rather than disease-specific strategies

studies in predictive biomarkers

and development of peer-review trial protocol for regular clinical trials.

Abstract

Controlled clinical trials of integrative therapies available to patients with rheumatoid arthritis (RA) improved dramatically in the past 20 years

largely because of the growing need and the methodologies improvement. Tripterygium wilfordii Hook. F.

a typical example of popular use herb

has been extensively studied in trials. However

clear and convincing evidence of integrative therapy

effectiveness and safety

remains insufficient to make decision. Many research efforts are hampered by standing problems with ‘syndrome’ recruitment failure. In addition

studies in predictive biomarkers

and development of peer-review trial protocol for regular clinical trials.

关键词

clinical trialrheumatoid arthritisIntegrative Medicinereview

Keywords

clinical trialrheumatoid arthritisIntegrative Medicinereview

references

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