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Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients
Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients
- 中国结合医学杂志（英文版） 2016年22卷第11期 页码：811-816
- Affiliations：
Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Institute of Digestive Disease Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,China
- Author bio：
- Funds：Supported by the National Natural Science Foundation of China (No. 81403355), the Young Foundation of Shanghai Health and Family Planning Commission (No. 20034y170), and the New Star Project of Shanghai Health and Family Planning Commission (No. ZY3-RCPY-2-2001)
DOI：10.1007/s11655-015-2118-1
中图分类号：纸质出版日期：2016，
网络出版日期：2015-10-26，
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Dai, Yc., Zhang, Yl., Wang, Lj. et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients., Chin. J. Integr. Med. 22, 811–816 (2016). https://doi.org/10.1007/s11655-015-2118-1
Yan-cheng Dai, Ya-li Zhang, Li-juan Wang, et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients[J]. Chinese Journal of Integrative Medicine, 2016,22(11):811-816.
Dai, Yc., Zhang, Yl., Wang, Lj. et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients., Chin. J. Integr. Med. 22, 811–816 (2016). https://doi.org/10.1007/s11655-015-2118-1 DOI：
Yan-cheng Dai, Ya-li Zhang, Li-juan Wang, et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients[J]. Chinese Journal of Integrative Medicine, 2016,22(11):811-816. DOI： 10.1007/s11655-015-2118-1.
摘要
Complementary and alternative medicine
particularly herbal therapy
is widely used by patients with ulcerative colitis (UC)
but controlled data are limited. To describe the clinical presentation and treatment strategies for UC in inpatients from Shanghai
China and to improve the therapeutic outcomes for patients with UC. Medical records from 247 patients with UC who were admitted to Longhua Hospital Affifiliated to Shanghai University of Traditional Chinese Medicine between January 2008 and June 2013 were analyzed for gender
age
course of the disease
clinical type
extent and severity of the disease
treatment strategies
and therapeutic outcomes. Gender ratios and disease onset of inpatients with UC in the Shanghai area were consistent with other reports in the literature. In contrast to previous studies
most patients exhibited disease of the left colon
over half of the patients had problems of the rectum or sigmoid colon
and most patients had either mild or moderate UC. Comparison of Sutherland Disease Actirity Index scores for patients treated with Chinese medicine (CM) and those treated with integrated CM and Western medicine revealed signifificant reductions in scores for both groups after treatment (P<0.01)
with no signifificant difference in therapeutic effects between groups (P=0.938). Herbal medicine has been widely used in patients with mild to moderate disease and as adjunct therapy in patients with moderate to severe disease. Therefore
the strategy was proposed for the treatment of UC with CM therapy based on 2 steps according to the stage of the disease
even in the clinical setting.
Abstract
Complementary and alternative medicine
particularly herbal therapy
is widely used by patients with ulcerative colitis (UC)
but controlled data are limited. To describe the clinical presentation and treatment strategies for UC in inpatients from Shanghai
China and to improve the therapeutic outcomes for patients with UC. Medical records from 247 patients with UC who were admitted to Longhua Hospital Affifiliated to Shanghai University of Traditional Chinese Medicine between January 2008 and June 2013 were analyzed for gender
age
course of the disease
clinical type
extent and severity of the disease
treatment strategies
and therapeutic outcomes. Gender ratios and disease onset of inpatients with UC in the Shanghai area were consistent with other reports in the literature. In contrast to previous studies
most patients exhibited disease of the left colon
over half of the patients had problems of the rectum or sigmoid colon
and most patients had either mild or moderate UC. Comparison of Sutherland Disease Actirity Index scores for patients treated with Chinese medicine (CM) and those treated with integrated CM and Western medicine revealed signifificant reductions in scores for both groups after treatment (P<0.01)
with no signifificant difference in therapeutic effects between groups (P=0.938). Herbal medicine has been widely used in patients with mild to moderate disease and as adjunct therapy in patients with moderate to severe disease. Therefore
the strategy was proposed for the treatment of UC with CM therapy based on 2 steps according to the stage of the disease
even in the clinical setting.
关键词
Ulcerative ColitisChinese Medicineretrospective studytreatment strategy
Keywords
Ulcerative ColitisChinese Medicineretrospective studytreatment strategy
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