Yan-bo REN, Jian-hua HUANG, Wai-jiao CAI, 等. Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(1):64-70.
Yan-bo REN, Jian-hua HUANG, Wai-jiao CAI, et al. Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(1):64-70.
Yan-bo REN, Jian-hua HUANG, Wai-jiao CAI, 等. Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(1):64-70. DOI: 10.1007/s11655-015-2136-z.
Yan-bo REN, Jian-hua HUANG, Wai-jiao CAI, et al. Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(1):64-70. DOI: 10.1007/s11655-015-2136-z.
Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine
摘要
Abstract
As the epitome of the modern regenerative medicine
stem cells were proposed in the basic sense no more than 200 years ago. However
the concept of "stem cells" existed long before the modern medical description. The hypothesis that all things
including our sentient body
were generated from a small origin was shared between Western and Chinese people. The ancient Chinese philosophers considered Jing (also known as essence) as the origin of life. In Chinese medicine (CM)
Jing is mainly stored in Kidney (Shen) and the so-called Shen-Jing (Kidney essence). Here
we propose that Shen-Jing is the CM term used to express the meaning of "origin and regeneration". This theoretical discovery has at least two applications. First
the actions underlying causing Shen-Jing deficiency
such as excess sexual intercourse
chronic diseases
and aging
might damage the function of stem cells. Second
a large number of Chinese herbs with Shen-Jing-nourishing efficacy had been proven to affect stem cell proliferation and differentiation. Therefore
if Shen-Jing in CM is equivalent with stem cells in regenerative medicine
higher effective modulators for regulating stem-cell behaviors from Kidney-tonifying herbs would be expected.