Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation

Bo Chen; Ming-yue Li; Yi Guo; Xue Zhao; Hui-min Calista Lim

doi:10.1007/s11655-016-2269-8

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Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation

ReviewPaper | Updated：2021-08-27

- Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation
- Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation
- 中国结合医学杂志（英文版） 2017年23卷第11期页码：878-880
- Affiliations：
  
  1. Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine,Tianjin,China
  2. Department of Clinical Practice Teaching, Tianjin University of Traditional Chinese Medicine,Tianjin,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81403457 and No. 81330088)
- DOI：10.1007/s11655-016-2269-8
  中图分类号：
- 纸质出版日期：2017，
  
  网络出版日期：2016-9-20，
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Chen, B., Li, My., Guo, Y. et al. Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation., Chin. J. Integr. Med. 23, 878–880 (2017). https://doi.org/10.1007/s11655-016-2269-8

Bo Chen, Ming-yue Li, Yi Guo, et al. Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation[J]. Chinese Journal of Integrative Medicine, 2017,23(11):878-880.
Chen, B., Li, My., Guo, Y. et al. Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation., Chin. J. Integr. Med. 23, 878–880 (2017). https://doi.org/10.1007/s11655-016-2269-8 DOI：

Bo Chen, Ming-yue Li, Yi Guo, et al. Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation[J]. Chinese Journal of Integrative Medicine, 2017,23(11):878-880. DOI： 10.1007/s11655-016-2269-8.

摘要

Exosomes are cell-derived vesicles that take part in intercellular signaling. Research has shown that acupuncture is closely related to affecting the functions of the mast cells in the local region of the acupoint

and stimulating the afferent nerve. Mast cells have a connection with the conduction within the meridians

and play an important role in immuno-regulation. The ‘synapse-like’ connection between the mast cells and nerve endings is the basis for the exchange of information between these two tissues. Exosome mediates mast exchange of information between mast cells and the nerves

starting the process of neuro-immuno regulation. Therefore

we propose that mast cell-derived exosomes mediate the neuro-immuno regulation at the local site of acupuncture

and this is one of the key factors resulting in the effectiveness of acupuncture.

Abstract

and stimulating the afferent nerve. Mast cells have a connection with the conduction within the meridians

starting the process of neuro-immuno regulation. Therefore

we propose that mast cell-derived exosomes mediate the neuro-immuno regulation at the local site of acupuncture

and this is one of the key factors resulting in the effectiveness of acupuncture.

关键词

mast cell-derived exosomesacupunctureneuro-immuno regulation

Keywords

mast cell-derived exosomesacupunctureneuro-immuno regulation

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