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An overview of epigenetics in Chinese medicine researches
An overview of epigenetics in Chinese medicine researches
- 中国结合医学杂志（英文版） 2017年23卷第9期 页码：714-720
- Affiliations：
Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine,Shanghai,China
- Author bio：
- Funds：Supported by the Key Program of National Natural Science Foundation of China (No. 81330084), "085" First-Class Discipline Construction Innovation Science and Technology Support Project of Shanghai University of Traditional Chinese Medicine (No. 085ZY1206) and E-Institutes of Shanghai Municipal Education Commission (No. E 03008);Conflict of Interests;The authors declare that they have no competing interests.;Author Contributions;Su SB designed and revised the review. Hu XQ drafted the manuscript. All authors read and approved the final manuscript.;Electronic Supplementary Material;: Supplementary material (Appendixes) is available in the online version of this article at http:// DOI: 10.1007/s11655-016-2274-y
DOI：10.1007/s11655-016-2274-y
中图分类号：纸质出版日期：2017，
网络出版日期：2016-12-20，
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Hu, Xq., Su, Sb. An overview of epigenetics in Chinese medicine researches., Chin. J. Integr. Med. 23, 714–720 (2017). https://doi.org/10.1007/s11655-016-2274-y
Xue-qing Hu, Shi-bing Su. An overview of epigenetics in Chinese medicine researches[J]. Chinese Journal of Integrative Medicine, 2017,23(9):714-720.
Hu, Xq., Su, Sb. An overview of epigenetics in Chinese medicine researches., Chin. J. Integr. Med. 23, 714–720 (2017). https://doi.org/10.1007/s11655-016-2274-y DOI：
Xue-qing Hu, Shi-bing Su. An overview of epigenetics in Chinese medicine researches[J]. Chinese Journal of Integrative Medicine, 2017,23(9):714-720. DOI： 10.1007/s11655-016-2274-y.
摘要
Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian countries. But the mechanisms underlying CM remain obscure
and need to be clarifified by modern biological subjects and methods. Recently
CM researches on epigenetics have gained obvious improvement following rapidly developed molecular technologies. In this review
we revealed mutual characteristics of epigenetics and CM
such as holism
yin-yang dynamic nature
reversibility and balance
and visceral manifestation. Moreover
epigenetic modifications
including DNA methylation
histone post-transcriptional modifications
micro RNA interference
etc. may help explore the molecular basis of CM syndrome classifification
and mechanisms of Chinese herbal medicine (CHM)
CHM compounds and Chinese herbal formulae activities. Meanwhile
CM and epigenetics might promote each other and jointly develop following the continuous progress of epigenetics in CM researches.
Abstract
Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian countries. But the mechanisms underlying CM remain obscure
and need to be clarifified by modern biological subjects and methods. Recently
CM researches on epigenetics have gained obvious improvement following rapidly developed molecular technologies. In this review
we revealed mutual characteristics of epigenetics and CM
such as holism
yin-yang dynamic nature
reversibility and balance
and visceral manifestation. Moreover
epigenetic modifications
including DNA methylation
histone post-transcriptional modifications
micro RNA interference
etc. may help explore the molecular basis of CM syndrome classifification
and mechanisms of Chinese herbal medicine (CHM)
CHM compounds and Chinese herbal formulae activities. Meanwhile
CM and epigenetics might promote each other and jointly develop following the continuous progress of epigenetics in CM researches.
关键词
Chinese Medicineepigeneticsmethylationhistone modificationChinese Herbal MedicineChinese herbal formulaChinese medicine syndrome
Keywords
Chinese Medicineepigeneticsmethylationhistone modificationChinese Herbal MedicineChinese herbal formulaChinese medicine syndrome
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