Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial
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OriginalPaper|Updated:2021-08-27
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Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial
Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial
中国结合医学杂志(英文版)2016年22卷第7期 页码:518-524
Affiliations:
1. Department of Acupuncture, Zhejiang Hospital,Hangzhou,China
2. Department of Neurobiology and Acupuncture Research, the Third College of Clinical Medicine, Zhejiang Chinese Medical University,Hangzhou,China
3. Department of Otolaryngology, Hospital of Traditional Chinese Medicine of Hangzhou City,Hangzhou,China
Author bio:
Funds:
Supported by the Key Project of Zhejiang Province Pharmaceutical Administration, China (No. 2010ZZ001) and Key Disciplines in Integrative Medicine of Zhejiang Province, China (No. 2012-XK-A04)
Chen, Yd., Jin, Xq., Yu, Mh. et al. Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial., Chin. J. Integr. Med. 22, 518–524 (2016). https://doi.org/10.1007/s11655-016-2453-x
Yi-dan Chen, Xiao-qing Jin, Mai-hong Yu, et al. Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial[J]. Chinese Journal of Integrative Medicine, 2016,22(7):518-524.
Chen, Yd., Jin, Xq., Yu, Mh. et al. Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial., Chin. J. Integr. Med. 22, 518–524 (2016). https://doi.org/10.1007/s11655-016-2453-xDOI:
Yi-dan Chen, Xiao-qing Jin, Mai-hong Yu, et al. Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial[J]. Chinese Journal of Integrative Medicine, 2016,22(7):518-524. DOI: 10.1007/s11655-016-2453-x.
Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial
摘要
To evaluate the effect and safety of acupuncture therapy on patients with moderate to severe allergic rhinitis. A non-randomized controlled design was used to compare between the acupuncture group and the medication group. The acupuncture group received 8-week acupuncture therapy
and the medication group received budesonide nasal spray with cetirizine tablets for 8 weeks. The clinical symptoms and signs were analyzed before treatment
at 4 and 8 weeks after the start of treatment
and at 12 weeks after the end of treatment. Furthermore
the clinical efficacy and safety indicators were compared between the two groups. A total of 76 participants consisting of 38 in each of the two groups were enrolled. The scores of each clinical symptom and sign
including sneezing
runny nose
stuffy nose
nasal itching
and turbinate edema
and the total scores decreased over time in both groups (all P<0.05); and no difference was found in the scores between the two groups (P>0.05). There was no statistically significant difference in the effective rates of the acupuncture group at 4 and 8 weeks after the start of treatment as well as at 12-week follow-up compared with those of the medication group (83.3% vs. 91.2%
and 94.4 % vs. 85.3%; and 80.6 % vs. 82.4%
all P>0.05). Experimental items including blood routine
urine routine
aspartate transaminase
alanine aminotransferase
urea nitrogen and creatinine were all in the normal reference ranges during the treatment in the acupuncture group. Acupuncture therapy has a comparable effect to the medication treatment on patients with moderate to severe allergic rhinitis
and it is safe with no severe adverse effects.
Abstract
To evaluate the effect and safety of acupuncture therapy on patients with moderate to severe allergic rhinitis. A non-randomized controlled design was used to compare between the acupuncture group and the medication group. The acupuncture group received 8-week acupuncture therapy
and the medication group received budesonide nasal spray with cetirizine tablets for 8 weeks. The clinical symptoms and signs were analyzed before treatment
at 4 and 8 weeks after the start of treatment
and at 12 weeks after the end of treatment. Furthermore
the clinical efficacy and safety indicators were compared between the two groups. A total of 76 participants consisting of 38 in each of the two groups were enrolled. The scores of each clinical symptom and sign
including sneezing
runny nose
stuffy nose
nasal itching
and turbinate edema
and the total scores decreased over time in both groups (all P<0.05); and no difference was found in the scores between the two groups (P>0.05). There was no statistically significant difference in the effective rates of the acupuncture group at 4 and 8 weeks after the start of treatment as well as at 12-week follow-up compared with those of the medication group (83.3% vs. 91.2%
and 94.4 % vs. 85.3%; and 80.6 % vs. 82.4%
all P>0.05). Experimental items including blood routine
urine routine
aspartate transaminase
alanine aminotransferase
urea nitrogen and creatinine were all in the normal reference ranges during the treatment in the acupuncture group. Acupuncture therapy has a comparable effect to the medication treatment on patients with moderate to severe allergic rhinitis
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