Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial

Jun Guo; Qing-he Gao; Fu Wang; Guo-jin Yu; Ji-wei Zhang; Yin Zeng; Qiang Geng; Bo-da Guo; Qiang Han

doi:10.1007/s11655-016-2456-7

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Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial

OriginalPaper | Updated：2021-08-27

- Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial
- Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial
- 中国结合医学杂志（英文版） 2016年22卷第12期页码：889-893
- Affiliations：
  
  1. Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Andrology, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin,China
  3. Xiangya School of Medicine, Central South University,Changsha,China
  4. Department of Andrology, Beijing Traditional Chinese Medicine Hospital Affilliated to Capital Medical University,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81273930)
- DOI：10.1007/s11655-016-2456-7
  中图分类号：
- 纸质出版日期：2016，
  
  网络出版日期：2016-5-12，
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Guo, J., Gao, Qh., Wang, F. et al. Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial., Chin. J. Integr. Med. 22, 889–893 (2016). https://doi.org/10.1007/s11655-016-2456-7

Jun Guo, Qing-he Gao, Fu Wang, et al. Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial[J]. Chinese Journal of Integrative Medicine, 2016,22(12):889-893.
Guo, J., Gao, Qh., Wang, F. et al. Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial., Chin. J. Integr. Med. 22, 889–893 (2016). https://doi.org/10.1007/s11655-016-2456-7 DOI：

Jun Guo, Qing-he Gao, Fu Wang, et al. Efficacy and safety of Qiaoshao Formula (翘芍方) on patients with lifelong premature ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A randomized controlled trial[J]. Chinese Journal of Integrative Medicine, 2016,22(12):889-893. DOI： 10.1007/s11655-016-2456-7.

摘要

To observe the effificacy and safety of Qiaoshao Formula (翘芍方

QSF) on patients with lifelong premature ejaculation (LPE) of Gan (Liver) depression and Shen (Kidney) defificiency syndrome. A total of 60 LPE patients were randomly divided into treatment (QSF) and control (dapoxetine) groups. The treatment group received QSF twice a day and the control group received dapoxetine 1 to 2 h prior to planned sexual intercourse for 4 weeks. The outcomes included intra-vaginal ejaculation latency time (IELT)

premature ejaculation diagnostic tool (PEDT)

clinical global impression of change (CGIC)

scores of Chinese medicine symptoms (CMSS)

sex life satisfaction (SLS) and adverse events (AEs). In the treated group

the median IELT was 3 min vs. 1.5 min before and after treatment (P<0.05). PEDT in the treated group was reduced to 11.76±1.68 from 15.83±2.30 after treatment (P<0.05). Besides

patient's SLS was improved from 1.30±0.05 to 6.30±0.04 (P<0.05)

and spouse's SLS was increased from 1.30±0.to 6.10±0.06 (P<0.05); CMSS was decrease from 14.86±3.02 to 9.62±2.87 (P<0.05). In addition

no significant AE was observed in both groups. QSF may be effective and safe on LPE patients with Gan depression and Shen defificiency syndrome.

Abstract

To observe the effificacy and safety of Qiaoshao Formula (翘芍方

premature ejaculation diagnostic tool (PEDT)

clinical global impression of change (CGIC)

scores of Chinese medicine symptoms (CMSS)

sex life satisfaction (SLS) and adverse events (AEs). In the treated group

the median IELT was 3 min vs. 1.5 min before and after treatment (P<0.05). PEDT in the treated group was reduced to 11.76±1.68 from 15.83±2.30 after treatment (P<0.05). Besides

patient's SLS was improved from 1.30±0.05 to 6.30±0.04 (P<0.05)

and spouse's SLS was increased from 1.30±0.to 6.10±0.06 (P<0.05); CMSS was decrease from 14.86±3.02 to 9.62±2.87 (P<0.05). In addition

no significant AE was observed in both groups. QSF may be effective and safe on LPE patients with Gan depression and Shen defificiency syndrome.

关键词

lifelong premature ejaculationQiaoshao FormulaChinese Medicinedapoxetineintra-vaginal ejaculation latency timepremature ejaculation diagnostic tool

Keywords

lifelong premature ejaculationQiaoshao FormulaChinese Medicinedapoxetineintra-vaginal ejaculation latency timepremature ejaculation diagnostic tool

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