Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study

Feng-xia Lin; Li-feng Tian; Cai-yun Lei; Chen-chen Ding; Li Shi; Si-fang Zhang

doi:10.1007/s11655-016-2581-3

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Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study

OriginalPaper | Updated：2021-08-27

- Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study
- Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study
- 中国结合医学杂志（英文版） 2017年23卷第9期页码：648-653
- Affiliations：
  
  1. Department of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University,Hunan,Changsha,China
  2. Department of Cardiology, Baoan Hospital of Traditional Chinese Medicine,Guangdong Province,Shenzhen,China
  3. Zhangmuba Army Sanatoriums of Hunan Military Region,Hunan,Changsha,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81273722);Conflict of Interests;The authors declare that they have no competing interests.;Author Contributions;Zhang SF, Lin FX, Tian LF conceived and designed the study;Tian LF, Lei CY, Ding CC, Shi L collected clinical data and follow-up record;Lin FX, Tian LF, Zhang SF analyzed the data;Lin FX, Zhang SF wrote the paper. All authors read and approved the final manuscript.
- DOI：10.1007/s11655-016-2581-3
  中图分类号：
- 纸质出版日期：2017，
  
  网络出版日期：2016-7-7，
Scan for full text
Lin, Fx., Tian, Lf., Lei, Cy. et al. Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study., Chin. J. Integr. Med. 23, 648–653 (2017). https://doi.org/10.1007/s11655-016-2581-3

Feng-xia Lin, Li-feng Tian, Cai-yun Lei, et al. Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study[J]. Chinese Journal of Integrative Medicine, 2017,23(9):648-653.
Lin, Fx., Tian, Lf., Lei, Cy. et al. Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study., Chin. J. Integr. Med. 23, 648–653 (2017). https://doi.org/10.1007/s11655-016-2581-3 DOI：

Feng-xia Lin, Li-feng Tian, Cai-yun Lei, et al. Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study[J]. Chinese Journal of Integrative Medicine, 2017,23(9):648-653. DOI： 10.1007/s11655-016-2581-3.

摘要

To investigate the effect of Chinese medicine (CM) on survival of patients with stage II and III colorectal cancer (CRC). A total of 295 patients who received chemotherapy were assigned to Group 1. The other 171 patients received the same chemotherapy treatment combined with the usage of CM Jianpi Jiedu Formula (健脾解毒方

JPJD) for more than 3 months (Group 2). Patients' survival time

relapse and metastasis

and cause of death were observed. Cox proportional hazard regression models were established for the analysis of the effect of independent factors on the survival prognosis of patients with CRC. The survival rate of patients in Group 2 was higher than that of Group 1 (P<0.05). Compared with Group 1

the mean survival time was prolonged by 5.594 months and the median survival time was prolonged by 6 months in Group 2 (P=0.004). Cox regression analysis indicated that CM combined with chemotherapy provided signifificant protective effect

as observed with the improvements in the survival rates of CRC patients (P<0.01). CM can improve the survival rate in patients with stage II and III CRC.

Abstract

JPJD) for more than 3 months (Group 2). Patients' survival time

relapse and metastasis

as observed with the improvements in the survival rates of CRC patients (P<0.01). CM can improve the survival rate in patients with stage II and III CRC.

关键词

Chinese MedicineIntegrative MedicineJianpi Jiedu Formulacolorectal cancerSurvival Period

Keywords

Chinese MedicineIntegrative MedicineJianpi Jiedu Formulacolorectal cancerSurvival Period

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