Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice

Jung-Hee Jang; Deuk-Joo Lee; Chang-Hwan Bae; Ki-Tae Ha; Sunoh Kwon; Hi-Joon Park; Dae-Hyun Hahm; Hyejung Lee; Seungtae Kim

doi:10.1007/s11655-016-2609-8

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Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice

OriginalPaper | Updated：2021-08-27

- Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice
- Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice
- 中国结合医学杂志（英文版） 2017年23卷第3期页码：215-220
- Affiliations：
  
  1. School of Korean Medicine, Pusan National University, Yangsan, Republic of Korea
  2. Acupuncture and Meridian Science Research Center, Kyung Hee University, Seoul, Republic of Korea
  3. Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine,Chicago,USA
- Author bio：
- Funds：
  
  Supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP, No. NRF- 2013R1A1A1005580)
- DOI：10.1007/s11655-016-2609-8
  中图分类号：
- 纸质出版日期：2017，
  
  网络出版日期：2016-9-1，
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Jang, JH., Lee, DJ., Bae, CH. et al. Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice., Chin. J. Integr. Med. 23, 215–220 (2017). https://doi.org/10.1007/s11655-016-2609-8

Jung-Hee Jang, Deuk-Joo Lee, Chang-Hwan Bae, et al. Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice[J]. Chinese Journal of Integrative Medicine, 2017,23(3):215-220.
Jang, JH., Lee, DJ., Bae, CH. et al. Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice., Chin. J. Integr. Med. 23, 215–220 (2017). https://doi.org/10.1007/s11655-016-2609-8 DOI：

Jung-Hee Jang, Deuk-Joo Lee, Chang-Hwan Bae, et al. Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice[J]. Chinese Journal of Integrative Medicine, 2017,23(3):215-220. DOI： 10.1007/s11655-016-2609-8.

摘要

To clarify the effects of acupuncture stimulation at Zusanli (ST 36) on the hormonal changes. Eight-week-old male C57BL/6 mice received acupuncture stimulation at acupoint ST 36 or Quchi (LI 11) once a day for 3 or 5 days in the acupuncture-stimulated groups

but not received in the normal group (n=6 in each group). On day 3 or 5

animals were given 0.1 mL of charcoal orally with a bulbed steel needle

30 min after the last acupuncture stimulation. Ten minutes later

mice were anesthetized

and the intestinal transit and the concentrations of vasoactive intestinal peptide (VIP)

motilin

ghrelin and gastrin in the serum were measured. Compared to no acupuncture stimulation

acupuncture stimulation at ST 36 for 5 days increased the intestinal transit and down-regulated the concentration of VIP and up-regulated the concentrations of motilin

ghrelin and gastrin (P<0.05 or 0.01)

whereas acupuncture stimulation at LI 11 did not change them signifificantly (P>0.05). Acupuncture stimulation at ST 36 for 5 days enhances the small intestinal motility and regulates the secretion of hormones related to small intestinal motility.

Abstract

but not received in the normal group (n=6 in each group). On day 3 or 5

animals were given 0.1 mL of charcoal orally with a bulbed steel needle

30 min after the last acupuncture stimulation. Ten minutes later

mice were anesthetized

and the intestinal transit and the concentrations of vasoactive intestinal peptide (VIP)

motilin

ghrelin and gastrin in the serum were measured. Compared to no acupuncture stimulation

acupuncture stimulation at ST 36 for 5 days increased the intestinal transit and down-regulated the concentration of VIP and up-regulated the concentrations of motilin

ghrelin and gastrin (P<0.05 or 0.01)

关键词

acupunctureGastrointestinal Motilityvasoactive intestinal peptidemotilinghrelingastrin

Keywords

acupunctureGastrointestinal Motilityvasoactive intestinal peptidemotilinghrelingastrin

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