Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome
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OriginalPaper|Updated:2021-08-27
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Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome
Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome
中国结合医学杂志(英文版)2017年23卷第11期 页码:845-849
Affiliations:
1. Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases,Beijing,China
2. Department of Cardiology, Aviation General Hospital,Beijing,China
3. Institute of Basic Medical Sciences, Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
4. Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
Author bio:
Funds:
Supported by National Basic Research Program of China (973 program, No. 2015CB554404)
Ma, Cy., Liu, Jh., Liu, Jx. et al. Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome., Chin. J. Integr. Med. 23, 845–849 (2017). https://doi.org/10.1007/s11655-016-2746-0
Cai-yun Ma, Jing-hua Liu, Jian-xun Liu, et al. Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome[J]. Chinese Journal of Integrative Medicine, 2017,23(11):845-849.
Ma, Cy., Liu, Jh., Liu, Jx. et al. Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome., Chin. J. Integr. Med. 23, 845–849 (2017). https://doi.org/10.1007/s11655-016-2746-0DOI:
Cai-yun Ma, Jing-hua Liu, Jian-xun Liu, et al. Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome[J]. Chinese Journal of Integrative Medicine, 2017,23(11):845-849. DOI: 10.1007/s11655-016-2746-0.
Relationship between two blood stasis syndromes and inflammatory factors in patients with acute coronary syndrome
摘要
To investigate the relationship between inflammatory factors and two Chinese medicine (CM) syndrome types of qi stagnation and blood stasis (QSBS) and qi deficiency and blood stasis (QDBS) in patients with acute coronary syndrome (ACS). Sixty subjects with ACS
whose pathogenesis changes belongs to qi disturbance blood stasis syndrome
were divided into 2 groups: 30 in the QSBS group and 30 in the QDBS group. The comparative analysis on them was carried out through comparing general information
coronary angiography and inflammatory factors including intracellular adhesion molecule-1 (ICAM-1)
chitinase-3-like protein 1 (YKL-40) and lipoprotein-associated phospholipase A2 (Lp-PLA2). Compared with the QSBS group
Lp-PLA2 and YKL-40 levels in the QDBS group showed no-significant difference (P>0.05); ICAM-1 was significantly higher in the QDBS group than in the QSBS group in the pathological processes of qi disturbance and blood stasis syndrome of ACS (P<0.05). Inflammatory factor ICAM-1 may be an objective basis for syndrome typing of QSBS and QDBS
which provides a research direction for standardization research of CM syndrome types.
Abstract
To investigate the relationship between inflammatory factors and two Chinese medicine (CM) syndrome types of qi stagnation and blood stasis (QSBS) and qi deficiency and blood stasis (QDBS) in patients with acute coronary syndrome (ACS). Sixty subjects with ACS
whose pathogenesis changes belongs to qi disturbance blood stasis syndrome
were divided into 2 groups: 30 in the QSBS group and 30 in the QDBS group. The comparative analysis on them was carried out through comparing general information
coronary angiography and inflammatory factors including intracellular adhesion molecule-1 (ICAM-1)
chitinase-3-like protein 1 (YKL-40) and lipoprotein-associated phospholipase A2 (Lp-PLA2). Compared with the QSBS group
Lp-PLA2 and YKL-40 levels in the QDBS group showed no-significant difference (P>0.05); ICAM-1 was significantly higher in the QDBS group than in the QSBS group in the pathological processes of qi disturbance and blood stasis syndrome of ACS (P<0.05). Inflammatory factor ICAM-1 may be an objective basis for syndrome typing of QSBS and QDBS
which provides a research direction for standardization research of CM syndrome types.
关键词
coronary heart diseaseChinese Medicineqi deficiency and blood stasis syndromeqi stagnation and blood stasis syndromeinflammationintracellular adhesion molecule-1chitinase-3-like protein 1lipoprotein-associated phospholipase A2
Keywords
coronary heart diseaseChinese Medicineqi deficiency and blood stasis syndromeqi stagnation and blood stasis syndromeinflammationintracellular adhesion molecule-1chitinase-3-like protein 1lipoprotein-associated phospholipase A2
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相关机构
Beijing University of Chinese Medicine
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences
Peking University First Hospital
Institute of Shanghai Municipal Education Commission, Shanghai University of Traditional Chinese Medicine, Shanghai
College of Health Information Technology and Management, Shanghai University of Medicine and Health Sciences