Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China
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OriginalPaper|Updated:2021-08-27
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Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China
Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China
中国结合医学杂志(英文版)2018年24卷第12期 页码:891-896
Affiliations:
1. Department of Acquired Immune Deficiency Syndrome Treatment and Research Center, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou,China
2. Henan Key Laboratory of Viral Diseases Control with Traditional Chinese Medicine,Zhengzhou,China
3. Traditional Chinese Medicine Center for Acquired Immune Deficiency Syndrome Prevention and Treatment, China Academy of Traditional Chinese Medicine,Beijing,China
Author bio:
Funds:
Supported by the National Natural Science Foundation of China (No. 81403342 and No. U1604287), the Science and Technology Program of Henan Province (No. 172102310325, No. 172102310199, No. 142102310511), the National Special Science and Technology Program on Major Infectious Diseases of China (2012ZX10005010-001) and Special of Scientific Research of Traditional Chinese Medicine of Henan Province in China (No. 2015ZY02097, No. 2016ZY2036, and No. 2015ZY01004)
Xu, Ql., Guo, Hj., Jin, Yt. et al. Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China., Chin. J. Integr. Med. 24, 891–896 (2018). https://doi.org/10.1007/s11655-017-2418-8
Qian-lei Xu, Hui-jun Guo, Yan-tao Jin, et al. Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China[J]. Chinese Journal of Integrative Medicine, 2018,24(12):891-896.
Xu, Ql., Guo, Hj., Jin, Yt. et al. Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China., Chin. J. Integr. Med. 24, 891–896 (2018). https://doi.org/10.1007/s11655-017-2418-8DOI:
Qian-lei Xu, Hui-jun Guo, Yan-tao Jin, et al. Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China[J]. Chinese Journal of Integrative Medicine, 2018,24(12):891-896. DOI: 10.1007/s11655-017-2418-8.
Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China
摘要
To analyze the effect of Chinese medicine (CM) on mortality and quality of life (QOL) of acquired immunodefificiency syndrome (AIDS) patients treated with combined antiretroviral therapy (cART). A random sample of AIDS patients enrolled in the National Chinese Medicine Treatment Trial Program (NCMTP) that met the inclusion criteria was included in this study. NCMTP patients were included as the CM+cART group
and those not in the NCMTP were included as the cART group. Survival from September 2004 to September 2012 was analyzed by retrospective cohort study. QOL was analyzed by cross-sectional study. The retrospective cohort study included 528 AIDS patients
322 in the CM+cART group and 206 in the cART group. After 8 years
the mortality in the CM+cART group was 3.3/100 person-years
which was lower than the cART group of 5.3/100 person-years (P<0.05). The hazard ratio (HR) for mortality in the cART group was 1.6 times that of the CM+cART group by Cox proportional hazard model analysis. After controlling for gender
age
marital status
education
and CD4+ T-cell count
the HR was 1.9 times higher in the cART group compared with the CM+cART group (P<0.05). The cross-sectional study investigated 275 AIDS patients. The mean scores of all QOL domains except spirituality/personal beliefs were higher in the CM+cART group than in the cART group (P<0.05). For AIDS patients
CM could help to prolong life
decrease mortality
and improve QOL. However
there were limitations in the study
so prospective studies should be carried out to confifirm our primary results.
Abstract
To analyze the effect of Chinese medicine (CM) on mortality and quality of life (QOL) of acquired immunodefificiency syndrome (AIDS) patients treated with combined antiretroviral therapy (cART). A random sample of AIDS patients enrolled in the National Chinese Medicine Treatment Trial Program (NCMTP) that met the inclusion criteria was included in this study. NCMTP patients were included as the CM+cART group
and those not in the NCMTP were included as the cART group. Survival from September 2004 to September 2012 was analyzed by retrospective cohort study. QOL was analyzed by cross-sectional study. The retrospective cohort study included 528 AIDS patients
322 in the CM+cART group and 206 in the cART group. After 8 years
the mortality in the CM+cART group was 3.3/100 person-years
which was lower than the cART group of 5.3/100 person-years (P<0.05). The hazard ratio (HR) for mortality in the cART group was 1.6 times that of the CM+cART group by Cox proportional hazard model analysis. After controlling for gender
age
marital status
education
and CD4+ T-cell count
the HR was 1.9 times higher in the cART group compared with the CM+cART group (P<0.05). The cross-sectional study investigated 275 AIDS patients. The mean scores of all QOL domains except spirituality/personal beliefs were higher in the CM+cART group than in the cART group (P<0.05). For AIDS patients
CM could help to prolong life
decrease mortality
and improve QOL. However
there were limitations in the study
so prospective studies should be carried out to confifirm our primary results.
关键词
acquired immunodefificiency syndromemortalityquality of lifeChinese Medicine
Keywords
acquired immunodefificiency syndromemortalityquality of lifeChinese Medicine
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