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Review of Anemone raddeana Rhizome and its pharmacological effects
Review of Anemone raddeana Rhizome and its pharmacological effects
- 中国结合医学杂志（英文版） 2018年24卷第1期 页码：72-79
- Affiliations：
1. Medical College, Hangzhou Normal University,Hangzhou,China
2. Suzhou Dongrui Pharmaceutical Co., Ltd.,Suzhou,China
3. Traditional Chinese Medicine College, Guangdong Pharmaceutical University,Guangzhou,China
4. Department of Acupucture, Hangzhou Traditional Chinese Medicine Hospital,Hangzhou,China
- Author bio：
- Funds：Supported by the Natural Science Foundation of Zhejiang Province, China (No. LY16H270018)
DOI：10.1007/s11655-017-2901-2
中图分类号：纸质出版日期：2018，
网络出版日期：2017-10-6，
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Wang, Sl., Zhao, Zk., Sun, Jf. et al. Review of Anemone raddeana Rhizome and its pharmacological effects., Chin. J. Integr. Med. 24, 72–79 (2018). https://doi.org/10.1007/s11655-017-2901-2
Shu-ling Wang, Zhen-kun Zhao, Jian-feng Sun, et al. Review of Anemone raddeana Rhizome and its pharmacological effects[J]. Chinese Journal of Integrative Medicine, 2018,24(1):72-79.
Wang, Sl., Zhao, Zk., Sun, Jf. et al. Review of Anemone raddeana Rhizome and its pharmacological effects., Chin. J. Integr. Med. 24, 72–79 (2018). https://doi.org/10.1007/s11655-017-2901-2 DOI：
Shu-ling Wang, Zhen-kun Zhao, Jian-feng Sun, et al. Review of Anemone raddeana Rhizome and its pharmacological effects[J]. Chinese Journal of Integrative Medicine, 2018,24(1):72-79. DOI： 10.1007/s11655-017-2901-2.
摘要
The chemical compositions of Anemone raddeana Rhizome
a kind of traditional Chinese medicine
were reviewed
along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism
and is rich in triterpenoid saponins
most of which are pentacyclic
with oleanane as the nucleus. So far
37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous
antimicrobial
anti-inflammatory
analgesic
antipyretic
anticonvulsive
antihistaminic
and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However
the herb also has hemolytic effects and can be toxic
which limits its clinical application. Further studies are needed on the pharmaceutical functions
mechanisms
and immunological responses to contribute to the herb's clinical applications.
Abstract
The chemical compositions of Anemone raddeana Rhizome
a kind of traditional Chinese medicine
were reviewed
along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism
and is rich in triterpenoid saponins
most of which are pentacyclic
with oleanane as the nucleus. So far
37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous
antimicrobial
anti-inflammatory
analgesic
antipyretic
anticonvulsive
antihistaminic
and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However
the herb also has hemolytic effects and can be toxic
which limits its clinical application. Further studies are needed on the pharmaceutical functions
mechanisms
and immunological responses to contribute to the herb's clinical applications.
关键词
Anemone raddeana Rhizomephytochemical constituentpharmacological effectanticancerousantimicrobialanti-inflammatoryanalgesicChinese Medicine
Keywords
Anemone raddeana Rhizomephytochemical constituentpharmacological effectanticancerousantimicrobialanti-inflammatoryanalgesicChinese Medicine
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