Guo, C., Rao, Xr. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease., Chin. J. Integr. Med. 24, 403–405 (2018). https://doi.org/10.1007/s11655-017-2926-6
Chuan Guo, Xiang-rong Rao. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease[J]. Chinese Journal of Integrative Medicine, 2018,24(6):403-405.
Guo, C., Rao, Xr. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease., Chin. J. Integr. Med. 24, 403–405 (2018). https://doi.org/10.1007/s11655-017-2926-6DOI:
Chuan Guo, Xiang-rong Rao. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease[J]. Chinese Journal of Integrative Medicine, 2018,24(6):403-405. DOI: 10.1007/s11655-017-2926-6.
Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease
摘要
Chronic kidney disease (CKD) is a major disease that threatens human health. With the progression of CKD
the risk of cardiovascular death increases
which is associated with the elevated levels of uremic toxins (UTs). Representative toxins such as indoxyl sulfate and p-cresyl sulfate are involed in CKD progression and cardiovascular events inseparable from the key role of endothelial dysfunction. The therapeutic strategies of UTs are aimed at signaling pathways that target the levels and damage of toxins in modern medicine. There is a certain relevance between toxins and "turbid toxin" in the theory of Chinese medicine (CM). CM treatments have been demonstrated to reduce the damage of gut-derived toxins to the heart
kidney and blood vessels. Modern medicine still lacks evidence-based therapies
so it is necessary to explore the treatments of CM.
Abstract
Chronic kidney disease (CKD) is a major disease that threatens human health. With the progression of CKD
the risk of cardiovascular death increases
which is associated with the elevated levels of uremic toxins (UTs). Representative toxins such as indoxyl sulfate and p-cresyl sulfate are involed in CKD progression and cardiovascular events inseparable from the key role of endothelial dysfunction. The therapeutic strategies of UTs are aimed at signaling pathways that target the levels and damage of toxins in modern medicine. There is a certain relevance between toxins and "turbid toxin" in the theory of Chinese medicine (CM). CM treatments have been demonstrated to reduce the damage of gut-derived toxins to the heart
kidney and blood vessels. Modern medicine still lacks evidence-based therapies
so it is necessary to explore the treatments of CM.
关键词
chronic kidney diseaseuremic toxinstherapeutic strategiesChinese Medicine
Keywords
chronic kidney diseaseuremic toxinstherapeutic strategiesChinese Medicine
references
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相关作者
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相关机构
Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine
Georg-August-Universität Göttingen, Göttingen
The Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics’ Ministry of Public Health
Medical Informatics Center, Peking University
Department of Hospital Management, Peking University Health Science Center, Peking University