Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method

Shi-huan TANG; Dan SHEN; Hong-jun YANG

doi:10.1007/s11655-017-2957-z

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Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method

Original Article | Updated：2021-08-27

- Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method
- Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method
- Chinese Journal of Integrative Medicine 2019年25卷第11期页码：861-866
- Affiliations：
  
  Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing (100700), China
- Author bio：
  
  Correspondence to: Prof. YANG Hong-jun, Tel: 86-10-57730848, E-mail: hongjun0420@vip.sina.com
- Funds：
  
  the National Nature Science Foundation of China(81330086;81203005);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ070830)
- DOI：10.1007/s11655-017-2957-z
  中图分类号：
- 纸质出版日期：2019-11-01，
  
  网络出版日期：2017-08-24，
  
  录用日期：2015-02-22
Scan for full text
Shi-huan TANG, Dan SHEN, Hong-jun YANG. Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method[J]. Chinese Journal of Integrative Medicine, 2019,25(11):861-866.

Shi-huan TANG, Dan SHEN, Hong-jun YANG. Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method[J]. Chinese Journal of Integrative Medicine, 2019,25(11):861-866.
Shi-huan TANG, Dan SHEN, Hong-jun YANG. Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method[J]. Chinese Journal of Integrative Medicine, 2019,25(11):861-866. DOI： 10.1007/s11655-017-2957-z.

Shi-huan TANG, Dan SHEN, Hong-jun YANG. Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method[J]. Chinese Journal of Integrative Medicine, 2019,25(11):861-866. DOI： 10.1007/s11655-017-2957-z.

摘要

Abstract

Objective:

To analyze the composition rules of oral prescriptions in the treatment of headache

stomachache and dysmenorrhea recorded in National Standard for Chinese Patent Drugs (NSCPD) enacted by Ministry of Public Health of China and then make comparison between them to better understand pain treatment in different regions of human body.

Methods:

Constructed NSCPD database had been constructed in 2014. Prescriptions treating the three pain-related diseases were searched and screened from the database. Then data mining method such as association rules analysis and complex system entropy method integrated in the data mining software Traditional Chinese Medicine Inheritance Support System (TCMISS) were applied to process the data.

Results:

Top 25 drugs with high frequency in the treatment of each disease were selected

and 51

33 and 22 core combinations treating headache

stomachache and dysmenorrhea respectively were mined out as well.

Conclusions:

The composition rules of the oral prescriptions for treating headache

stomachache and dysmenorrhea recorded in NSCPD has been summarized. Although there were similarities between them

formula varied according to different locations of pain. It can serve as an evidence and reference for clinical treatment and new drug development.

关键词

Keywords

Chinese patent drugheadachestomachachedysmenorrheapainTraditional Chinese Medicine Inheritance Support Systemformulating principle

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