Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome

Wen Sun; Jian Yu; Gu-lan Zeng; Bing-feng Zhang

doi:10.1007/s11655-017-2961-3

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Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome

OriginalPaper | Updated：2021-08-27

- Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome
- Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome
- 中国结合医学杂志（英文版） 2018年24卷第8期页码：579-583
- Affiliations：
  
  1. Department of Traditional Chinese Medicine, Children’s Hospital of Fudan University,Shanghai,China
  2. Department of Pediatrics, Xiamen Hospital of Traditional Chinese Medicine,Fujian Province,Xiamen,China
  3. Department of Gastroenterology, Children’s Hospital of Fudan University,Shanghai,China
- Author bio：
- Funds：
  
  Supported by Shanghai Municipal Commission of Health and Family Planning (No. 2010QL031B)
- DOI：10.1007/s11655-017-2961-3
  中图分类号：
- 纸质出版日期：2018，
  
  网络出版日期：2017-8-17，
Scan for full text
Sun, W., Yu, J., Zeng, Gl. et al. Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome., Chin. J. Integr. Med. 24, 579–583 (2018). https://doi.org/10.1007/s11655-017-2961-3

Wen Sun, Jian Yu, Gu-lan Zeng, et al. Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome[J]. Chinese Journal of Integrative Medicine, 2018,24(8):579-583.
Sun, W., Yu, J., Zeng, Gl. et al. Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome., Chin. J. Integr. Med. 24, 579–583 (2018). https://doi.org/10.1007/s11655-017-2961-3 DOI：

Wen Sun, Jian Yu, Gu-lan Zeng, et al. Preliminary Research on Syndrome Types of Chinese Medicine in Children with Primary Nephrotic Syndrome[J]. Chinese Journal of Integrative Medicine, 2018,24(8):579-583. DOI： 10.1007/s11655-017-2961-3.

摘要

To provide an objective reference for the syndrome types of Chinese medicine (CM) associated with pediatric primary nephrotic syndrome (PNS). A cross-sectional study was performed. Data on clinical symptoms

CM syndrome types

biochemical indices

and medications used were collected from 98 children with PNS. Then

the correlation between CM syndromes and biochemical indices

as well as medications used

was analyzed. The four most common symptoms in children with PNS were brown urine

red tongue

excessive sweating

and swelling of the face and limbs. The syndromes of qi deficiency of Fei (Lung) and Shen (Kidney) (FSQD) and yin deficiency of Gan (Liver) and Shen (GSYD) were the most common main CM syndrome types. FSQD syndrome score correlated significantly with the total cholesterol level

urine protein/creatinine ratio

and urine IgG and albumin levels (P<0.01 or P<0.05). The use of maintenance glucocorticoids combined with immunosuppressive agents correlated with FSQD syndrome

and the use of maintenance glucocorticoids alone correlated with GSYD syndrome (P<0.05). Two of the most common CM syndrome types were FSQD and GSYD syndromes. FSQD syndrome may be caused by some factors related to lipid levels

protein loss

and the use of immunosuppressive agents. The use of maintenance glucocorticoids may cause GSYD syndrome

Abstract

CM syndrome types

biochemical indices

and medications used were collected from 98 children with PNS. Then

the correlation between CM syndromes and biochemical indices

as well as medications used

was analyzed. The four most common symptoms in children with PNS were brown urine

red tongue

excessive sweating

urine protein/creatinine ratio

and urine IgG and albumin levels (P<0.01 or P<0.05). The use of maintenance glucocorticoids combined with immunosuppressive agents correlated with FSQD syndrome

protein loss

and the use of immunosuppressive agents. The use of maintenance glucocorticoids may cause GSYD syndrome

关键词

primary nephrotic syndromeChinese MedicineSyndrome Typecorrelation analysis

Keywords

primary nephrotic syndromeChinese MedicineSyndrome Typecorrelation analysis

references

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