Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial
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Original Article|Updated:2021-08-27
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Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial
Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial
Chinese Journal of Integrative Medicine2019年25卷第2期 页码:91-95
Affiliations:
1.Department of Urology and Andrology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai (200032), China
2.Shanghai Qigong Research Institute, Shanghai University of Traditional Chinese Medicine, Shanghai (200030), China
3.Department of Vascular Surgery, Shanghai Traditional Chinese Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai (200082), China
4.School of Chinese Medicine, the University of Hong Kong, Hong Kong SAR, China
5.Department of Chinese Medicine, the University of Hong Kong-Shenzhen Hospital, Shenzhen (518053), China
Author bio:
Correspondence to: Prof. ZHANG Zhang-jin, Tel: 852-39176455, E-mail: zhangzj@hku.hk
Jian YING, Min-jie ZHOU, Hai-yong CHEN, 等. Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(2):91-95.
Jian YING, Min-jie ZHOU, Hai-yong CHEN, et al. Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(2):91-95.
Jian YING, Min-jie ZHOU, Hai-yong CHEN, 等. Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(2):91-95. DOI: 10.1007/s11655-018-2797-5.
Jian YING, Min-jie ZHOU, Hai-yong CHEN, et al. Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(2):91-95. DOI: 10.1007/s11655-018-2797-5.
Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial
摘要
Abstract
Objective:
2
To evaluate the efficacy and safety of essential oil treatment for type Ⅲ chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Methods:
2
A randomized controlled trial was conducted from December 2014 to October 2015. Seventy type Ⅲ CP/CPPS patients were assigned to the essential oil group (35 cases) or almond placebo oil control group (35 cases) by a random number table. The oil was smeared by self-massage on the suprapubic and sacral region once a day for 4 weeks. The National Institutes of Health Chronic Prostatitis Syndrome Index (NIH-CPSI) and expressed prostatic secretions (EPS) were examined. The primary outcome was NIH-CPSI pain domain. The secondary outcomes included other NIH-CPSI domains and laboratory examinations of EPS. Adverse events were also observed.
Results:
2
Sixty-six subjects completed the full 4-week treatment. There was no significant difference between almond oil control and essential oil groups in terms of the total score of NIH-CPSI
pain
quality of life and urination domain scores of NIH-CPSI and EPS examinations (
P
>
0.05). In the essential oil group
pain between rectum and testicles (perineum) in the domain of pain or discomfort was significantly reduced at week 2 and week 4 compared with almond oil control group (
P
<
0.01). No serious adverse events occurred.
Conclusion:
2
The essential oil may reduce the pain or discomfort in the perineum region in patients with CP/CPPS. (Registration No. ChiCTR-IPR-14005448)
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