Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer

Jin-long Duan; Bo Deng; Guo-hui Song; Zhi-feng Chen; Yan-wei Gong; Yu-hua He; Li-qun Jia

doi:10.1007/s11655-018-2840-6

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Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer

OriginalPaper | Updated：2021-08-27

- Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer
- Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer
- 中国结合医学杂志（英文版） 2018年24卷第10期页码：746-751
- Affiliations：
  
  1. School of Clinical Medicine, Beijing University of Chinese Medicine,Beijing,China
  2. Department of Oncology of Integrative Chinese and Western Medicine, China-Japan Friendship Hospital,Beijing,China
  3. Department of Oncology, Ci County Tumor Hospital,Hebei Province,Handan,China
  4. Department of Oncology, Fourth Affiliated Hospital of Hebei Medical University,Shijiazhuang,China
- Author bio：
- Funds：
  
  Supported by the National Twelfth Five-Year Initiatives Project (No. 2012BAJ18B05)
- DOI：10.1007/s11655-018-2840-6
  中图分类号：
- 纸质出版日期：2018，
  
  网络出版日期：2018-4-17，
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Duan, Jl., Deng, B., Song, Gh. et al. Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer., Chin. J. Integr. Med. 24, 746–751 (2018). https://doi.org/10.1007/s11655-018-2840-6

Jin-long Duan, Bo Deng, Guo-hui Song, et al. Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer[J]. Chinese Journal of Integrative Medicine, 2018,24(10):746-751.
Duan, Jl., Deng, B., Song, Gh. et al. Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer., Chin. J. Integr. Med. 24, 746–751 (2018). https://doi.org/10.1007/s11655-018-2840-6 DOI：

Jin-long Duan, Bo Deng, Guo-hui Song, et al. Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer[J]. Chinese Journal of Integrative Medicine, 2018,24(10):746-751. DOI： 10.1007/s11655-018-2840-6.

摘要

To differentiate patients with esophageal cancer or premalignant lesions from the high-risk population for preliminary screening of esophageal cancer using a feature index determined by a computer-aided tongue information acquisition and processing system (DS01-B). Totally

213 patients diagnosed with esophageal cancer or premalignant lesions and 2

840 normal subjects were collected including primarily screened and reexamined

all of them were confirmed with histological examinations. Their tongue color space values and manifestation features were extracted by DS01-B and analyzed. Firstly

the analysis of variance was performed to differentiate normal subjects from patients with esophageal cancer and premalignant lesions. Secondly

the logistic regression was conducted using 10 features and gender

age to get a predictive equation of the possibility of esophageal cancer or premalignant lesions. Lastly

the equation was tested by subjects undergoing primary screening. Saturation (S) values in the HSV color space showed significant differences between patients with esophageal cancer and normal subjects or those with mild atypical hyperplasia (P<0.05); blue-to-yellow (b) values in the Lab color space showed significant differences between patients with esophageal cancer or premalignant lesions and normal subjects (P<0.05). Logistic regression analysis showed that the computer-aided tongue inspection approach had an accuracy of 72.3% (2008/2776) in identifying patients with esophageal cancer or premalignant lesions for preliminary screening in high-risk population. Computer-aided tongue inspection

with descriptive and quantitative profile as described in this study

could be applied as a cost- and timeefficient

non-invasive approach for preliminary screening of esophageal cancer in high-risk population.

Abstract

213 patients diagnosed with esophageal cancer or premalignant lesions and 2

840 normal subjects were collected including primarily screened and reexamined

all of them were confirmed with histological examinations. Their tongue color space values and manifestation features were extracted by DS01-B and analyzed. Firstly

the analysis of variance was performed to differentiate normal subjects from patients with esophageal cancer and premalignant lesions. Secondly

the logistic regression was conducted using 10 features and gender

age to get a predictive equation of the possibility of esophageal cancer or premalignant lesions. Lastly

with descriptive and quantitative profile as described in this study

could be applied as a cost- and timeefficient

non-invasive approach for preliminary screening of esophageal cancer in high-risk population.

关键词

esophageal cancerpreliminary differential diagnosiscomputer-aided tongue inspectionlogistic regression

Keywords

esophageal cancerpreliminary differential diagnosiscomputer-aided tongue inspectionlogistic regression

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