Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial

Hu-dan PAN; Xiao-li QI; Lei WANG; Jing-yan HE; Jiu-li LIU; Yun-bi ZHANG; Ye TIAN; Xing-wu DUAN; Hao-yu YANG; Yan-ping BAI

doi:10.1007/s11655-018-2940-8

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Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial

Original Article | Updated：2021-08-27

- Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial
- Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial
- Chinese Journal of Integrative Medicine 2019年25卷第4期页码：259-263
- Affiliations：
  
  1.Department of Dermatology, China-Japan Friendship Hospital, Beijing (100029), China
  2.Macau University of Science and Technology, Macau (999078), China
  3.Department of Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin (300120), China
  4.Department of Dermatology, Shunyi District Branch of Beijing Hospital of Traditional Chinese Medicine, Beijing (101300), China
  5.Department of Dermatology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing (100700), China
  6.Department of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Beijing (100010), China
- Author bio：
  
  Correspondence to: Prof. BAI Yan-ping, Tel: 86-10-84205002, E-mail: zhi@tsinghua.edu.cn
- Funds：
  
  the External Treatment Technology Project, Chinese Medicine Science in Beijing, Undertaken by the Beijing Administration of Traditional Chinese Medicine(WZF2012-97)
- DOI：10.1007/s11655-018-2940-8
  中图分类号：
- 纸质出版日期：2019-04-01，
  
  网络出版日期：2019-02-27，
  
  录用日期：2018-03-26
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Hu-dan PAN, Xiao-li QI, Lei WANG, 等. Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(4):259-263.

Hu-dan PAN, Xiao-li QI, Lei WANG, et al. Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(4):259-263.
Hu-dan PAN, Xiao-li QI, Lei WANG, 等. Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(4):259-263. DOI： 10.1007/s11655-018-2940-8.

Hu-dan PAN, Xiao-li QI, Lei WANG, et al. Whether Fire-Needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2019,25(4):259-263. DOI： 10.1007/s11655-018-2940-8.

摘要

Abstract

Objective:

To observe the clinical effectiveness and safety of fire-needle therapy

an external approach of Chinese medicine in treating plaque psoriasis.

Methods:

This study was a two-parallel-arm randomized controlled trial. A total of 151 participants with plaque psoriasis were randomly assigned to the fire-needle therapy group (treatment group

76 cases) or the control group (75 cases) at a 1:1 allocation ratio using SAS software. All participants received Oral Huoxue Jiedu Decoction (活血解毒汤

HXJDD) and applied externally vaseline cream twice a day. Participants in the treatment group received fire-needle therapy once weekly for 4 weeks plus HXJDD and vaseline cream applied the same as the control group. The primary outcome measure was Psoriasis Area and Severity Index (PASI) score

and the secondary outcomes were Dermatology Life Quality Index (DLQL)

and Hamilton Anxiety Rating Scale (HAMA)

as well as Chinese medicine (CM) syndrome score and photos of target lesions. The indices were evaluated before and after treatment.

Results:

Sixty-eight patients in each group completed the study. The treatment group has not yet achieved significant improvement in PASI score (

0.05) compared to the control group. However

significant differences were found between the two groups in relieving CM syndrome (

0.05) and improving quality of life (

0.05).

Conclusions:

Fire-needle appears to be safe and may have benefit for psoriasis

the short-term treatment and small sample size limit the conclusions of this study. Further rigorous randomized controlled trials with longer treatment are recommended.

关键词

Keywords

fire-needle therapyChinese medicineHuoxue Jiedu Decoctionplaque psoriasisrandomized controlled trial

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