Herb-Induced Liver Injury: A Global Concern

Neil Kaplowitz

doi:10.1007/s11655-018-3004-4

Your Location：

Home >

Browse articles >

Herb-Induced Liver Injury: A Global Concern

OriginalPaper | Updated：2021-08-27

- Herb-Induced Liver Injury: A Global Concern
- Herb-Induced Liver Injury: A Global Concern
- 中国结合医学杂志（英文版） 2018年24卷第9期页码：643-644
- Affiliations：
  
  USC Research Center for Liver Disease, USC Keck School of Medicine,Los Angeles,USA
- Author bio：
- Funds：
- DOI：10.1007/s11655-018-3004-4
  中图分类号：
- 纸质出版日期：2018，
  
  网络出版日期：2018-5-3，
Scan for full text
Kaplowitz, N. Herb-Induced Liver Injury: A Global Concern., Chin. J. Integr. Med. 24, 643–644 (2018). https://doi.org/10.1007/s11655-018-3004-4

Neil Kaplowitz. Herb-Induced Liver Injury: A Global Concern[J]. Chinese Journal of Integrative Medicine, 2018,24(9):643-644.
Kaplowitz, N. Herb-Induced Liver Injury: A Global Concern., Chin. J. Integr. Med. 24, 643–644 (2018). https://doi.org/10.1007/s11655-018-3004-4 DOI：

Neil Kaplowitz. Herb-Induced Liver Injury: A Global Concern[J]. Chinese Journal of Integrative Medicine, 2018,24(9):643-644. DOI： 10.1007/s11655-018-3004-4.

摘要

Chinese medicine and herb medicine though used to treat liver diseases are an important cause of liver injury. Many phytochemicals have the potential to injure the liver

some in a dose-related fashion and more often in an idiosyncratic fashion

meaning occurrence is uncommon to rare in the population using these treatments. As is the case with pharmaceuticals

the phytochemicals are usually tolerated despite either no or mild transient subclinical injury but rarely in some susceptible patients cause moderate to severe liver injury which is likely mediated by the adaptive immune system.

Abstract

Chinese medicine and herb medicine though used to treat liver diseases are an important cause of liver injury. Many phytochemicals have the potential to injure the liver

some in a dose-related fashion and more often in an idiosyncratic fashion

meaning occurrence is uncommon to rare in the population using these treatments. As is the case with pharmaceuticals

关键词

herb-induced liver injurydiagnosis and managementguidelineChinese Medicine

Keywords

herb-induced liver injurydiagnosis and managementguidelineChinese Medicine

references

Wang JB, Zhu Y, Bai ZF, Wang FS, Li XH, Xiao XH, et al. Guidelines for the diagnosis and management of herb-induced liver injury. Chin J Integr Med 2018;24:696–706.

Favreau JT, Ryu ML, Braunstein G, Orshansky G, Park SS, Coody GL, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2006;136:590–595.

Fong TL, Klontz KC, Canas–Coto A, Casper SJ, Durazo FA, Davern TJ 2nd, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol 2010;105:1561–1566.

Roytman MM, Pörzgen P, Lee CL, Huddleston L, Kuo TT, Bryant–Greenwood P, et al. Outbreak of severe hepatitis linked to weight–loss supplement OxyELITE Pro. Am J Gastroenterol 2002;109:1296–1298.

Larrey D, Vial T, Pauwels A, Castot A, Biour M, David M, et al. Hepatitis after germander (Teucriumchamaedrys) administration: another instance of herbal medicine hepatotoxicity. Ann Intern Med 1992;117:129–132.

Russmann S, Lauterburg BH, Helbling A. Kava hepatotoxicity. Ann Intern 2001;135:68–69.

Dara L, Liu ZX, Kaplowitz N. Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications. Liver Int 2016; 36:158–165.

WöllS, Kim SH, Greten HJ. Animal plant warfare and secondary metabolite evolution. Nat Prod Bioprospect 2013;3:1–7.

FULL TEXT LINK

More>

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Guidelines for the Diagnosis and Management of Herb-Induced Liver Injury

Guideline for postmarketing Chinese medicine pharmacoeconomic evaluation

Future view and development of immunology: Exploring the immunology based on Chinese medicine and culture

Cost-effectiveness analysis of combined Chinese medicine and Western medicine for ischemic stroke patients

Objective tongue inspection on 142 liver cancer patients with damp-heat syndrome