Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity

Wen-bin LIU; Sai LI; Xiao-ling YU; Tie-ying DAI; Rui-lan GAO

doi:10.1007/s11655-019-3031-9

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Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity

Feature Article | Updated：2021-08-27

- Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity
- Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity
- Chinese Journal of Integrative Medicine 2019年25卷第7期页码：483-489
- Affiliations：
  
  Institute of Hematology Research, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou (310006), China
- Author bio：
  
  [ "Prof. GAO Rui-lan" ]
- Funds：
  
  the National Natural Science Foundation of China(81774068);National Major Project for the Innovative New Drugs of "the 13th Five-year Plan"(2016ZX09101071)
- DOI：10.1007/s11655-019-3031-9
  中图分类号：
- 纸质出版日期：2019-07-01，
  
  录用日期：2018-10-08
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Wen-bin LIU, Sai LI, Xiao-ling YU, 等. Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity[J]. Chinese Journal of Integrative Medicine, 2019,25(7):483-489.

Wen-bin LIU, Sai LI, Xiao-ling YU, et al. Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity[J]. Chinese Journal of Integrative Medicine, 2019,25(7):483-489.
Wen-bin LIU, Sai LI, Xiao-ling YU, 等. Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity[J]. Chinese Journal of Integrative Medicine, 2019,25(7):483-489. DOI： 10.1007/s11655-019-3031-9.

Wen-bin LIU, Sai LI, Xiao-ling YU, et al. Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity[J]. Chinese Journal of Integrative Medicine, 2019,25(7):483-489. DOI： 10.1007/s11655-019-3031-9.

摘要

Abstract

Chronic primary immune thrombocytopenia (CITP) is the most common acquired autoimmune disease that seriously threaten the physical and mental health of patients. Compared with Western medicine treatment

the intervention and treatment of Chinese medicine (CM) has shown certain therapeutic advantages. This paper reviewed the new pathogenesis progress on T cell immune abnormality in CITP

and CM studies on interferes effects of cellular immune regulation of CITP in recent years. Qi deficiency failing to control blood and internal obstruction of blood stasis are the two common types of CM syndromes in CITP patients

the corresponding treatments include invigorating Pi (Spleen)

supplementing qi

activating blood

as well as tonifying qi and activating yang

regulating Gan (Liver) to invigorate Pi. The authors also mentioned the problems in the research field of CM for CTIP treatment

and put forward new ideas for the research in the future.

关键词

Keywords

chronic immune thrombocytopeniacellular immunityChinese medicine

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