Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine

Yong-rong WU; Gao-yan KUANG; Fang-guo LU; Heng-xin WANG; Min LU; Qing ZHOU

doi:10.1007/s11655-019-3224-2

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Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine

Review | Updated：2021-08-27

- Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine
- Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine
- Chinese Journal of Integrative Medicine 2019年25卷第9期页码：716-720
- Affiliations：
  
  1.TAN Xin-hua Famous Medical Studio, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha (410007), China
  2.Department of Orthopedics, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha (410007), China
  3.Department of Medical College, Hunan University of Chinese Medicine, Changsha (410208), China
  4.Hinye Pharmaceutical Co., Ltd., Changsha (410331), China
- Author bio：
  
  Correspondence to: Prof. ZHOU Qing, Tel: 86-731-85600441, E-mail: 310094@hnucm.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(81574004;81874476);Natural Science Foundation of Hunan Province of China(2019JJ50462);TAN Xin-hua Famous Medical Studio(004-04)
- DOI：10.1007/s11655-019-3224-2
  中图分类号：
- 纸质出版日期：2019-09-01，
  
  录用日期：2019-03-19
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Yong-rong WU, Gao-yan KUANG, Fang-guo LU, 等. Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(9):716-720.

Yong-rong WU, Gao-yan KUANG, Fang-guo LU, et al. Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(9):716-720.
Yong-rong WU, Gao-yan KUANG, Fang-guo LU, 等. Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(9):716-720. DOI： 10.1007/s11655-019-3224-2.

Yong-rong WU, Gao-yan KUANG, Fang-guo LU, et al. Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2019,25(9):716-720. DOI： 10.1007/s11655-019-3224-2.

摘要

Abstract

Chinese medicine (CM) has a good clinical effect on osteoarthritis (OA)

but the mechanism is not very clear. Evidence-based medicine researches have shown that intestinal flora plays a role in the pathogenesis and succession of OA. Intestinal flora affects the efficacy of CM

and CM can affect the balance of intestinal flora. This paper focuses on the relationship between intestinal flora

intestinal microenvironment

brain-gut axis

metabolic immunity and OA

and preliminarily expound the significance of intestinal flora in the pathogenesis of OA and the mechanism of CM intervention. The above discussion will be of great significance in the prevention and treatment of OA by CM from the perspective of intestinal flora.

关键词

Keywords

osteoarthritisintestinal florapathogenesistreatmentmechanism of Chinese medicine

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