Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs

Hui LUO; Qiao-ling TANG; Ya-xi SHANG; Shi-bing LIANG; Ming YANG; Nicola Robinson; Jian-ping LIU

doi:10.1007/s11655-020-3192-6

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Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs

Hot Topic | Updated：2021-08-23

- Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs
- Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs
- Chinese Journal of Integrative Medicine 2020年26卷第4期页码：243-250
- Affiliations：
  
  1.Institute for Tibetan Medicine, China Tibetology Research Center, Beijing (100101), China
  2.Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing (100029), China
  3.School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing (100029), China
  4.School of Health and Social Care, London South Bank University, London (SE1 0AA), UK
  5.Institute of Integrated Traditional Chinese Medicine and Western Medicine, Guangzhou Medical University, Guangzhou (510120), China
- Author bio：
  
  Correspondence to: Prof. LIU Jian-ping, E-mail:jianping_l@hotmail.com
- Funds：
  
  the National Natural Science Foundation of China(81830115);the Overseas Expertise Project, Ministry of Education of China(MS20080009)
- DOI：10.1007/s11655-020-3192-6
  中图分类号：
- 纸质出版日期：2020-04-01，
  
  网络出版日期：2020-02-17，
  
  录用日期：2020-02-13
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Hui LUO, Qiao-ling TANG, Ya-xi SHANG, 等. Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs[J]. Chinese Journal of Integrative Medicine, 2020,26(4):243-250.

Hui LUO, Qiao-ling TANG, Ya-xi SHANG, et al. Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs[J]. Chinese Journal of Integrative Medicine, 2020,26(4):243-250.
Hui LUO, Qiao-ling TANG, Ya-xi SHANG, 等. Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs[J]. Chinese Journal of Integrative Medicine, 2020,26(4):243-250. DOI： 10.1007/s11655-020-3192-6.

Hui LUO, Qiao-ling TANG, Ya-xi SHANG, et al. Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs[J]. Chinese Journal of Integrative Medicine, 2020,26(4):243-250. DOI： 10.1007/s11655-020-3192-6.

摘要

Abstract

Objective:

Since December 2019

an outbreak of corona virus disease 2019 (COVID-19) occurred in Wuhan

and rapidly spread to almost all parts of China. This was followed by prevention programs recommending Chinese medicine (CM) for the prevention. In order to provide evidence for CM recommendations

we reviewed ancient classics and human studies.

Methods:

Historical records on prevention and treatment of infections in CM classics

clinical evidence of CM on the prevention of severe acute respiratory syndrome (SARS) and H1N1 influenza

and CM prevention programs issued by health authorities in China since the COVID-19 outbreak were retrieved from different databases and websites till 12 February

2020. Research evidence included data from clinical trials

cohort or other population studies using CM for preventing contagious respiratory virus diseases.

Results:

The use of CM to prevent epidemics of infectious diseases was traced back to ancient Chinese practice cited in

Huangdi's Internal Classic

(Huang Di Nei Jing) where preventive effects were recorded. There were 3 studies using CM for prevention of SARS and 4 studies for H1N1 influenza. None of the participants who took CM contracted SARS in the 3 studies. The infection rate of H1N1 influenza in the CM group was significantly lower than the non-CM group (relative risk 0.36

95% confidence interval 0.24–0.52;

=4). For prevention of COVID-19

23 provinces in China issued CM programs. The main principles of CM use were to tonify qi to protect from external pathogens

disperse wind and discharge heat

and resolve dampness. The most frequently used herbs included

Radix astragali

(Huangqi)

Radix glycyrrhizae

(Gancao)

Radix saposhnikoviae

(Fangfeng)

Rhizoma Atractylodis Macrocephalae

(Baizhu)

Lonicerae Japonicae Flos

(Jinyinhua)

and

Fructus forsythia

(Lianqiao).

Conclusions:

Based on historical records and human evidence of SARS and H1N1 influenza prevention

Chinese herbal formula could be an alternative approach for prevention of COVID-19 in high-risk population. Prospective

rigorous population studies are warranted to confirm the potential preventive effect of CM.

关键词

Keywords

Chinese medicinecorona virus disease 2019 (COVID-19)prevention programclinical evidencereview

references

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