药用植物亲缘学：回顾和未来方向

Xue GONG; Min YANG; Chun-nian HE; Ya-qiong BI; Chun-hong ZHANG; Min-hui LI; Pei-gen XIAO

doi:10.1007/s11655-020-3270-9

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药用植物亲缘学：回顾和未来方向

Review | Updated：2022-06-27

- 药用植物亲缘学：回顾和未来方向
- Plant Pharmacophylogeny: Review and Future Directions
- Chinese Journal of Integrative Medicine 2022年28卷第6期页码：567-574
- Affiliations：
  
  1.Department of Pharmacy, Baotou Medical College, Baotou,Inner Mongolia Autonomous Region (014040), China
  2.Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing(100193), China
  3.Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot (010020),China
  4.Guangxi Botanical Garden of Medicinal Plants, Nanning (530000), China
  5.Inner Mongolia Key Laboratory of Characteristic Geoherbs Resources Protection and Utilization,Baotou Medical College, Baotou, Inner Mongolia Autonomous Region (014040), China
- Author bio：
  
  Prof. LI Min-hui, E-mail: prof_liminhui@yeah.net;
  Prof. XIAO Pei-gen, E-mail: pgxiao@implad.ac.cn
- Funds：
  
  the National Natural Science Foundation of China(81760776;81874336);Natural Science Foundation of Inner Mongolia Autonomous Region(2018ZD134)
- DOI：10.1007/s11655-020-3270-9
  中图分类号：
- 纸质出版日期：2022-06-01，
  
  网络出版日期：2020-11-10，
  
  录用日期：2020-04-20
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Xue GONG, Min YANG, Chun-nian HE, 等. 药用植物亲缘学：回顾和未来方向[J]. Chinese Journal of Integrative Medicine, 2022,28(6):567-574.

Xue GONG, Min YANG, Chun-nian HE, et al. Plant Pharmacophylogeny: Review and Future Directions[J]. Chinese Journal of Integrative Medicine, 2022,28(6):567-574.
Xue GONG, Min YANG, Chun-nian HE, 等. 药用植物亲缘学：回顾和未来方向[J]. Chinese Journal of Integrative Medicine, 2022,28(6):567-574. DOI： 10.1007/s11655-020-3270-9.

Xue GONG, Min YANG, Chun-nian HE, et al. Plant Pharmacophylogeny: Review and Future Directions[J]. Chinese Journal of Integrative Medicine, 2022,28(6):567-574. DOI： 10.1007/s11655-020-3270-9.

摘要

近年来

药用植物资源的开发利用显著增加. 不同进化水平的各种药用植物已经鉴定出许多活性成分

包括甾体生物碱、皂苷、萜类和苷类. 关于药用植物的化学分类、分子系统发育和药理活性的研究越来越受到重视. 药用植物亲缘学主要研究药用植物的系统发育、化学成分和疗效 (药理活性和传统疗效) 之间相关性的跨学科课题. 此外

它还是实现中医药资源研究和开发的基本工具. 这篇文献综述基于植物群和物种之间的遗传关系

重点介绍了药物系统发育的形成过程、研究内容、应用和药用植物亲缘学的未来方向.

Abstract

Medicinal plants have provided numerous medicinal active ingredients for thousands of years and these ingredients have been used in Chinese medicine (CM) and traditional pharmacologies worldwide. Recently

the exploitation and utilisation of medicinal plant resources has increased significantly. The results of the studies have led to the identification of many active components

such as steroidal alkaloids

saponins

terpenoids

and glycosides

in various medicinal plants with different evolutionary levels. Moreover

research on the chemical classification

molecular phylogeny

and pharmacological activity of medicinal plants is increasing in popularity. Pharmacophylogeny is an interdisciplinary topic that studies the correlation between plant phylogeny

chemical composition

and curative effects (pharmacological activity and the traditional curative effect) of medicinal plants. In addition

it provides the basic tools to enable research and development of CM resources. This literature review

based on the genetic relationship between phytogroup and species

highlights the formation process

research content

applications

and future directions of pharmacophylogeny.

关键词

Keywords

pharmacophylogenyphytogroupmolecular phylogenychemical compositioncurative effect

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